Best TWAS P=2.36e-09 · Best GWAS P=1.28e-12 conditioned to 4.75e-05
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Cells Transformed fibroblasts | WDR70 | 0.06 | 0.03 | lasso | 8 | 0.03 | 0.0035 | -5.0 | 5.5 | 5.1e-08 | -0.72 | 0.31 | 0.53 | FALSE |
2 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | C5orf42 | 0.04 | 0.05 | lasso | 3 | 0.04 | 0.0011 | -6.2 | 6.0 | 2.4e-09 | -0.92 | 0.01 | 0.79 | TRUE |