TWAS
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Traits
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Traits
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Arm fat-free mass (left)
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chr5:36,684,550-38,450,430
Best TWAS P=2.36e-09 · Best GWAS P=1.28e-12 conditioned to 4.75e-05
36.6M
36.8M
37M
37.2M
37.4M
37.6M
37.8M
38M
38.2M
38.4M
0
2
4
6
8
10
12
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
The Cancer Genome Atlas
Ovarian Serous Cystadenocarcinoma
C5orf42
0.04
0.05
lasso
3
0.04
0.0011
-6.2
6.0
2.4e-09
-0.92
0.01
0.79
TRUE
1
GTEx
Cells Transformed fibroblasts
WDR70
0.06
0.03
lasso
8
0.03
0.0035
-5.0
5.5
5.1e-08
-0.72
0.31
0.53
FALSE