Best TWAS P=3.6e-12 · Best GWAS P=3.85e-14 conditioned to 0.00104
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Esophagus Gastroesophageal Junction | CDKN2C | 0.14 | 0.11 | enet | 17 | 0.12 | 0.00003 | 7.6 | -7.0 | 3.6e-12 | -0.86 | 0.02 | 0.94 | TRUE |
2 | METSIM | Adipose | AGBL4 | 0.02 | 0.02 | lasso | 5 | 0.02 | 0.00126 | 5.8 | -5.9 | 3.0e-09 | 0.01 | 0.75 | 0.17 | TRUE |