Best TWAS P=3.91e-19 · Best GWAS P=7.61e-21 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | GPR126 | 0.06 | 0.04 | lasso | 4 | 0.04 | 0.00061 | -8.8 | 8.9 | 3.9e-19 | -0.98 | 0.02 | 0.96 | TRUE |
| 2 | METSIM | Adipose | GPR126 | 0.05 | 0.01 | blup | 429 | 0.02 | 0.00019 | -4.1 | 6.2 | 6.1e-10 | -0.74 | 0.11 | 0.89 | FALSE |
| 3 | The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | NMBR | 0.09 | 0.01 | blup | 46 | 0.04 | 0.03380 | 3.8 | -5.3 | 8.8e-08 | 0.12 | 0.02 | 0.65 | TRUE |