Best TWAS P=3.26e-09 · Best GWAS P=7.25e-15 conditioned to 1.84e-08
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Muscularis | NEGR1 | 0.13 | 0.04 | lasso | 3 | 0.05 | 5.1e-04 | -4.6 | 5.2 | 2.2e-07 | -0.66 | 0.72 | 0.11 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | NEGR1 | 0.24 | 0.15 | lasso | 8 | 0.22 | 1.3e-27 | 4.7 | 5.9 | 3.3e-09 | -0.48 | 0.98 | 0.02 | TRUE |