Best TWAS P=1.11e-08 · Best GWAS P=7.56e-09 conditioned to 0.0765
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | PIP4K2A | 0.20 | 0.18 | lasso | 1 | 0.18 | 6.4e-21 | 5.7 | -5.7 | 1.1e-08 | -0.94 | 0.00 | 1.00 | TRUE |
| 2 | GTEx | Artery Tibial | CASC10 | 0.05 | 0.06 | lasso | 4 | 0.02 | 1.3e-02 | 4.2 | 5.2 | 2.3e-07 | 0.18 | 0.25 | 0.49 | TRUE |
| 3 | GTEx | Cells Transformed fibroblasts | PIP4K2A | 0.24 | 0.20 | lasso | 2 | 0.19 | 2.9e-14 | 5.3 | -5.2 | 2.0e-07 | -0.81 | 0.04 | 0.96 | FALSE |