[Hub]/) : Traits : Arm predicted mass (left) :

chr1:106,906,072-108,296,508

Best TWAS P=1.17e-08 · Best GWAS P=3.4e-09 conditioned to 1.64e-10

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous PRMT6 0.17 0.10 enet 6 0.11 5.1e-09 5.2 -5.3 1.3e-07 -0.09 0.26 0.74 FALSE
2 GTEx Colon Transverse PRMT6 0.29 0.24 lasso 7 0.19 1.4e-09 5.0 -5.3 1.3e-07 -0.09 0.34 0.66 FALSE
3 GTEx Esophagus Mucosa PRMT6 0.33 0.23 lasso 7 0.29 1.4e-19 5.1 -5.2 2.2e-07 -0.08 0.32 0.68 FALSE
4 GTEx Heart Left Ventricle PRMT6 0.16 0.12 enet 9 0.13 2.3e-07 5.0 -5.2 2.1e-07 -0.12 0.33 0.64 FALSE
5 GTEx Liver PRMT6 0.60 0.52 lasso 6 0.58 1.0e-19 5.0 -5.2 1.7e-07 -0.08 0.33 0.67 FALSE
6 GTEx Muscle Skeletal PRMT6 0.32 0.16 enet 13 0.16 2.8e-15 5.1 -5.7 1.2e-08 -0.08 0.32 0.68 TRUE
7 GTEx Thyroid PRMT6 0.19 0.17 enet 14 0.19 1.7e-14 5.0 -5.2 1.9e-07 -0.08 0.35 0.65 FALSE
8 The Cancer Genome Atlas Bladder Urothelial Carcinoma PRMT6 0.13 0.10 lasso 4 0.10 2.0e-08 5.0 -5.3 1.3e-07 -0.09 0.01 0.99 FALSE
9 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma PRMT6 0.09 0.03 blup 36 0.07 1.8e-04 5.0 -5.2 1.9e-07 -0.06 0.01 0.91 FALSE
10 The Cancer Genome Atlas Esophageal Carcinoma PRMT6 0.33 0.26 lasso 3 0.25 2.0e-08 5.0 -5.2 1.7e-07 -0.09 0.01 0.99 FALSE
11 The Cancer Genome Atlas Lung Squamous Cell Carcinoma PRMT6 0.11 0.12 enet 7 0.12 2.3e-13 5.1 -5.4 8.4e-08 -0.09 0.01 0.99 FALSE
12 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma PRMT6 0.09 0.08 blup 36 0.08 3.3e-06 5.0 -5.6 2.8e-08 -0.09 0.01 0.99 FALSE