Best TWAS P=1.97e-08 · Best GWAS P=3.24e-06 conditioned to 0.271
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Liver | ATXN7L2 | 0.39 | 0.04 | lasso | 12 | 0.21 | 1.3e-06 | 4.4 | 5.6 | 2e-08 | 0.69 | 0.04 | 0.64 | TRUE |
2 | The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | MYBPHL | 0.09 | 0.07 | blup | 46 | 0.06 | 5.7e-04 | 2.5 | 5.1 | 3e-07 | 0.57 | 0.01 | 0.26 | FALSE |