Best TWAS P=8.98e-09 · Best GWAS P=6.24e-14 conditioned to 3.16e-08
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adipose Visceral Omentum | RAD52 | 0.14 | 0.07 | lasso | 3 | 0.10 | 1.1e-05 | -4.5 | -5.7 | 9.0e-09 | -0.44 | 0.50 | 0.40 | TRUE |
2 | GTEx | Testis | RAD52 | 0.29 | 0.19 | lasso | 3 | 0.18 | 2.3e-08 | 5.9 | -5.3 | 1.5e-07 | -0.49 | 0.81 | 0.16 | FALSE |
3 | The Cancer Genome Atlas | Esophageal Carcinoma | RAD52 | 0.25 | 0.13 | blup | 66 | 0.19 | 1.1e-06 | 6.7 | -5.7 | 1.2e-08 | -0.61 | 0.00 | 0.99 | FALSE |