Best TWAS P=3.51e-19 · Best GWAS P=1.02e-16 conditioned to 2.22e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Visceral Omentum | NLRX1 | 0.14 | 0.03 | lasso | 5 | 0.03 | 9.6e-03 | 8.2 | -8.9 | 3.5e-19 | -0.93 | 0.01 | 0.96 | TRUE |
| 2 | GTEx | Pancreas | HINFP | 0.19 | 0.13 | lasso | 4 | 0.10 | 4.4e-05 | 3.9 | 5.3 | 8.8e-08 | 0.34 | 0.55 | 0.12 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | NLRX1 | 0.05 | 0.03 | enet | 5 | 0.05 | 2.4e-06 | 3.9 | -5.1 | 3.1e-07 | -0.13 | 0.02 | 0.46 | FALSE |
| 4 | The Cancer Genome Atlas | Prostate Adenocarcinoma | MPZL2 | 0.04 | 0.04 | blup | 55 | 0.04 | 9.2e-05 | -4.5 | -5.1 | 3.1e-07 | -0.24 | 0.01 | 0.86 | TRUE |
| 5 | The Cancer Genome Atlas | Prostate Adenocarcinoma | TREH | 0.05 | 0.05 | lasso | 2 | 0.04 | 2.7e-05 | 6.1 | 6.1 | 1.4e-09 | 0.71 | 0.00 | 0.99 | FALSE |
| 6 | The Cancer Genome Atlas | Thyroid Carcinoma | TREH | 0.27 | 0.18 | lasso | 3 | 0.21 | 8.6e-20 | 6.1 | 6.0 | 1.9e-09 | 0.68 | 0.00 | 1.00 | FALSE |