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Traits
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Traits
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Arm predicted mass (left)
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chr12:64,869,118-67,328,072
Best TWAS P=1.69e-11 · Best GWAS P=6.26e-54 conditioned to 4.31e-49
65M
65.5M
66M
66.5M
67M
0
10
20
30
40
50
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Heart Atrial Appendage
RBMS1P1
0.17
0.03
lasso
11
0.04
7.3e-03
9.0
-6.7
1.7e-11
-0.40
0.07
0.40
TRUE
1
GTEx
Adipose Visceral Omentum
LEMD3
0.14
0.05
lasso
8
0.05
1.1e-03
-4.6
-6.0
1.5e-09
0.11
0.28
0.42
TRUE
3
GTEx
Nerve Tibial
LEMD3
0.12
0.14
enet
13
0.16
2.0e-11
-4.5
-5.7
9.7e-09
0.11
0.50
0.50
FALSE
4
The Cancer Genome Atlas
Head and Neck Squamous Cell Carcinoma
LEMD3
0.02
0.02
blup
36
0.02
5.9e-03
-5.7
-5.3
1.5e-07
0.12
0.01
0.82
FALSE