Best TWAS P=2.66e-18 · Best GWAS P=1.65e-41 conditioned to 4.92e-22
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Breast Mammary Tissue (Male) | MRPL42 | 0.21 | -0.01 | lasso | 2 | -0.01 | 6.0e-01 | 8.8 | -8.7 | 2.7e-18 | -0.48 | 0.05 | 0.06 | TRUE |
| 2 | GTEx | Muscle Skeletal | MRPL42 | 0.07 | 0.02 | lasso | 3 | 0.04 | 1.5e-04 | -5.2 | -5.5 | 3.8e-08 | -0.17 | 0.69 | 0.01 | TRUE |
| 3 | YFS | Blood | SOCS2 | 0.06 | 0.04 | bslmm | 444 | 0.04 | 1.7e-12 | 5.8 | 7.2 | 6.2e-13 | 0.01 | 1.00 | 0.00 | TRUE |