Best TWAS P=7.91e-08 · Best GWAS P=1.54e-07 conditioned to 0.122
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Muscle Skeletal | ANKLE2 | 0.06 | 0.01 | enet | 17 | 0.03 | 8.8e-04 | 4.8 | 5.2 | 2.4e-07 | -0.03 | 0.01 | 0.87 | TRUE |
2 | GTEx | Testis | EP400NL | 0.37 | 0.30 | lasso | 5 | 0.36 | 6.0e-17 | 5.2 | -5.4 | 7.9e-08 | -0.87 | 0.01 | 0.99 | TRUE |
3 | YFS | Blood | EP400 | 0.06 | 0.08 | lasso | 7 | 0.08 | 5.4e-24 | 5.2 | -5.2 | 2.5e-07 | -0.99 | 0.01 | 0.99 | FALSE |