Best TWAS P=1.57e-09 · Best GWAS P=6.63e-09 conditioned to 0.742
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Lung | AL137059.1 | 0.11 | 0.01 | lasso | 6 | 0.02 | 5.0e-03 | -2.5 | -5.1 | 2.6e-07 | 0.34 | 0.16 | 0.17 | TRUE |
| 2 | GTEx | Muscle Skeletal | MTIF3 | 0.12 | 0.03 | lasso | 5 | 0.03 | 1.2e-03 | -4.9 | -5.2 | 2.6e-07 | 0.74 | 0.19 | 0.69 | FALSE |
| 3 | GTEx | Nerve Tibial | AL137059.1 | 0.10 | 0.02 | lasso | 3 | 0.03 | 2.9e-03 | 4.9 | -5.7 | 1.2e-08 | 0.71 | 0.02 | 0.94 | FALSE |
| 4 | GTEx | Testis | MTIF3 | 0.45 | 0.28 | lasso | 11 | 0.25 | 1.8e-11 | 4.9 | -5.5 | 3.9e-08 | 0.49 | 0.23 | 0.77 | FALSE |
| 5 | The Cancer Genome Atlas | Brain Lower Grade Glioma | GTF3A | 0.03 | 0.00 | enet | 8 | 0.01 | 2.3e-02 | 2.3 | 6.0 | 1.6e-09 | -0.63 | 0.01 | 0.82 | TRUE |