Best TWAS P=2.42e-08 · Best GWAS P=7.27e-10 conditioned to 0.00453
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | BTBD7 | 0.16 | 0.01 | lasso | 8 | 0.04 | 0.00036 | -5.7 | 5.5 | 3.9e-08 | -0.62 | 0.08 | 0.91 | FALSE |
| 2 | The Cancer Genome Atlas | Lung Adenocarcinoma | RIN3 | 0.05 | 0.00 | blup | 163 | 0.01 | 0.06020 | -2.5 | -5.4 | 5.1e-08 | 0.06 | 0.01 | 0.10 | TRUE |
| 3 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | BTBD7 | 0.02 | 0.01 | blup | 72 | 0.02 | 0.00677 | -5.4 | 5.2 | 2.3e-07 | -0.69 | 0.01 | 0.88 | FALSE |
| 4 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | BTBD7 | 0.11 | 0.03 | blup | 72 | 0.02 | 0.07950 | -5.7 | 5.6 | 2.4e-08 | -0.67 | 0.02 | 0.80 | TRUE |