Best TWAS P=6.1e-10 · Best GWAS P=5.62e-12 conditioned to 0.000864
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Mucosa | MARK3 | 0.11 | 0.03 | lasso | 4 | 0.04 | 1.5e-03 | 5.9 | 5.7 | 1.0e-08 | -0.01 | 0.05 | 0.79 | FALSE |
| 2 | GTEx | Thyroid | TRMT61A | 0.11 | 0.03 | lasso | 4 | 0.02 | 1.2e-02 | 5.9 | -5.5 | 3.2e-08 | -0.01 | 0.01 | 0.98 | FALSE |
| 3 | METSIM | Adipose | TRAF3 | 0.04 | 0.02 | enet | 7 | 0.04 | 4.5e-06 | 6.0 | 6.2 | 6.1e-10 | 0.79 | 0.05 | 0.94 | TRUE |
| 4 | YFS | Blood | MARK3 | 0.04 | 0.04 | lasso | 3 | 0.04 | 1.6e-12 | 5.9 | 5.9 | 3.7e-09 | -0.01 | 0.02 | 0.98 | TRUE |
| 5 | The Cancer Genome Atlas | Thyroid Carcinoma | MARK3 | 0.10 | 0.03 | blup | 61 | 0.03 | 4.0e-04 | -4.7 | -5.5 | 3.5e-08 | 0.04 | 0.03 | 0.15 | FALSE |