Best TWAS P=1.33e-09 · Best GWAS P=5.47e-10 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Spleen | VPS13C | 0.27 | 0.19 | lasso | 7 | 0.12 | 0.00066 | 4.7 | 5.1 | 2.9e-07 | -0.80 | 0.26 | 0.53 | FALSE |
| 2 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | C2CD4A | 0.09 | 0.11 | lasso | 1 | 0.08 | 0.00094 | -6.1 | -6.1 | 1.3e-09 | 0.99 | 0.02 | 0.84 | TRUE |
| 3 | The Cancer Genome Atlas | Thyroid Carcinoma | VPS13C | 0.07 | 0.03 | enet | 15 | 0.03 | 0.00053 | -6.1 | 5.2 | 2.3e-07 | -0.73 | 0.02 | 0.91 | FALSE |