TWAS hub - C2CD4A

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Head and Neck Squamous Cell Carcinoma	0.0273	0.0169	0.0073	0.012	0.015	0.007	NA	0.002	1.3e-02	0.0072	0.0540	NA	0.18000
2	TCGA	Testicular Germ Cell Tumors	0.0860	0.0530	0.0072	0.113	0.025	0.066	NA	0.079	8.7e-05	0.0460	0.0024	NA	0.00094

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Comparative height size at age 10	8.9	49.2	64.8	-5.8	-8.1
Type 2 Diabetes (T2D) (2012)	8.6	10.0	15.1	-2.2	-3.9
Sitting height	7.7	55.0	67.7	-6.5	-8.2
Trunk predicted mass	7.4	42.0	56.7	-5.2	-7.5
Trunk fat-free mass	7.3	41.8	56.5	-5.2	-7.5
Height	6.7	128.2	158.8	-9.9	-12.6
Lupus	6.1	9.2	10.5	3.2	2.8
Whole body water mass	6.0	34.0	46.3	-4.7	-6.8
Whole body fat-free mass	5.9	33.5	45.7	-4.6	-6.8
Arm fat-free mass (right)	5.6	28.7	39.3	-4.2	-6.3
Hearing difficulty/problems with background noise	5.5	8.8	9.0	-3.0	-2.9
Arm predicted mass (right)	5.4	27.8	38.4	-4.1	-6.2
Arm predicted mass (left)	5.4	27.5	36.8	-4.3	-6.1
Standing height	5.2	52.0	69.7	-5.9	-8.4
Arm fat-free mass (left)	5.2	26.1	34.8	-4.2	-5.9
Waist Hip Ratio (WHR)	4.9	22.0	24.5	4.4	4.9
Forced expiratory volume in 1-second (FEV1), predicted	4.5	9.3	12.2	-2.5	-3.5
Basal metabolic rate	4.5	24.8	33.7	-4.0	-5.8
Ever had hysterectomy (womb removed)	4.4	4.9	5.0	-2.2	-2.2
Unable to work because of sickness or disability	4.3	5.6	7.5	1.9	2.7
Friendships satisfaction	4.2	5.2	5.9	-2.2	-2.4
Leg fat-free mass (right)	4.1	21.9	30.0	-3.7	-5.5
Leg predicted mass (right)	4.1	22.0	30.2	-3.7	-5.5
Lung FEV1/FVC ratio	4.0	20.5	21.8	4.4	4.7
Leg predicted mass (left)	3.9	20.7	28.6	-3.6	-5.3
Hair/balding pattern: Pattern 2	3.9	4.9	7.9	1.4	2.8
Leg fat-free mass (left)	3.8	20.0	27.7	-3.5	-5.3
Medication: Paracetamol	3.7	6.1	6.5	2.5	2.4
Medication for hormone replacement therapy	3.6	4.0	4.5	-2.1	-1.9
Forced vital capacity (FVC), Best measure	3.5	12.7	16.7	-3.0	-4.1
Medication for pain relief, constipation, heartburn	3.5	6.0	7.0	-2.7	-2.2
Bilateral oophorectomy (both ovaries removed)	3.4	3.9	5.8	-2.4	-1.4
Forced vital capacity (FVC)	3.4	13.1	18.7	-2.7	-4.3
Hair/balding pattern: Pattern 4	2.8	6.9	9.0	-2.2	-3.0
Medication: Atorvastatin	2.8	3.4	3.4	1.8	1.9
Number of incorrect matches in round	2.7	4.5	5.2	2.0	2.3
Qualifications: A levels/AS levels or equivalent	2.6	5.9	6.9	-2.2	-2.6
Qualifications: College or University degree	2.6	8.1	11.4	-2.2	-3.4
Osteoarthritis (self-reported)	2.6	3.4	4.3	1.6	2.1
Fasting Glucose	2.5	3.0	6.0	0.0	-2.4
Ulcerative Colitis	2.5	3.7	4.0	2.0	1.8
Prospective memory result	2.5	3.1	4.6	1.2	2.1
Mean Putamen Volume	2.4	2.8	3.3	-1.8	-1.5
Diabetes (father)	2.4	2.9	5.8	0.2	-2.4
Impedance of leg (left)	2.4	11.6	16.8	2.5	4.1
Loud music exposure frequency	2.4	2.7	4.0	-2.0	-1.1
Impedance of whole body	2.4	12.1	16.7	2.7	4.1
Shortness of breath walking on level ground	2.3	2.7	3.3	1.8	1.5
Long-standing illness, disability or infirmity	2.3	3.5	3.6	1.9	1.9
Supplements: Calcium	2.3	2.6	3.3	1.8	1.4
Diabetes (mother)	2.1	2.7	3.9	-1.2	-2.0
Medication: Ventolin 100micrograms inhaler	2.1	2.7	5.3	-2.3	-0.2
Pulse wave peak to peak time	2.1	2.5	2.7	-1.5	-1.6
Systolic blood pressure, automated reading	2.0	5.8	6.9	2.6	2.2
Impedance of leg (right)	2.0	9.6	14.4	2.2	3.8
Impedance of arm (left)	2.0	9.3	12.5	2.5	3.5
Overall health rating	2.0	4.3	5.9	1.7	2.4
Age started oral contraceptive pill	2.0	2.5	2.9	-1.5	-1.7
Vascular/heart problems diagnosed by doctor	2.0	5.5	6.2	-2.2	-2.5
Medication: Ramipril	1.9	2.4	2.7	1.6	1.5
Impedance of arm (right)	1.9	9.1	12.8	2.3	3.6
Osteoporosis (self-reported)	1.9	2.4	3.0	1.7	1.3
Tinnitus: Yes, now most or all of the time	1.9	2.2	2.4	1.6	1.4
Medication: Paracetamol	1.9	2.9	2.9	1.7	1.7
Leg fat percentage (left)	1.8	6.6	8.7	2.1	3.0
Financial situation satisfaction	1.7	2.1	2.8	1.2	1.7
Pack years of smoking	1.7	2.5	4.0	1.0	2.0
HbA1C	1.6	1.8	2.7	1.6	1.0
Systolic Blood Pressure	1.6	8.1	8.5	2.9	2.8
Frequency of depressed mood in last 2 weeks	1.6	2.2	2.3	1.5	1.5
Pack years adult smoking proportion	1.6	2.4	4.2	0.8	2.0
Leg fat percentage (right)	1.6	5.9	8.0	2.0	2.8
Migraine (self-reported)	1.6	2.0	2.4	1.3	1.5
Handedness (chirality/laterality): Left-handed	1.6	1.9	3.3	0.7	1.8
Ever had stillbirth, spontaneous miscarriage or termination	1.6	1.7	2.3	-1.1	-1.5
Commuting to job workplace: Public transport	1.6	1.9	2.0	-1.3	-1.4
High cholesterol (Self-reported)	1.6	2.9	4.3	1.2	2.1
Breast cancer (self-reported)	1.5	1.7	3.0	1.7	0.7
Depression (Nagel 2018)	1.4	2.1	2.7	1.3	1.6
HDL Cholesterol	1.4	2.3	2.9	1.7	1.3
Asthma	1.4	2.7	4.6	-2.1	-0.9
Asthma (self-reported)	1.4	2.8	4.7	-2.2	-1.0
Illnesses of father: None of the above (group 1)	1.4	1.7	3.0	-1.7	-0.7
Cholesterol lowering medication	1.4	2.1	3.0	1.1	1.7
Alzheimer’s Disease (in father)	1.3	1.4	1.6	-1.2	-1.1
Blood Platelet Count	1.3	14.8	17.7	3.4	4.2
Heel bone mineral density (BMD) T-score, automated (left)	1.3	2.9	3.7	1.5	1.9
High blood pressure	1.3	3.7	4.5	1.7	2.1
Had other major operations	1.3	1.6	3.2	-0.3	-1.8
Weight	1.3	6.6	9.3	-2.0	-3.0
Hip circumference	1.3	5.8	7.1	-2.1	-2.7
Serious illness, injury or assault of a close relative in last 2 years	1.3	1.4	1.6	1.3	1.1
Forced expiratory volume in 1-second (FEV1), Best measure	1.3	4.2	5.4	-1.7	-2.3
Birth weight of first child	1.3	2.3	3.3	-1.1	-1.8
Chronic bronchitis/emphysema (mother)	1.3	1.5	2.3	-0.8	-1.5
Knee pain experienced in last month	1.3	2.0	2.2	1.5	1.4
Illnesses of father: Heart disease	1.3	1.8	2.2	1.5	1.2
Medication: Omeprazole (e.g. Zanprol)	1.3	1.6	2.2	1.0	1.5
Pain experienced in last month	1.3	2.1	2.2	-1.5	-1.4
Crohns Disease (2017)	1.2	2.6	4.2	-2.0	-1.0
Rheumatoid Arthritis	1.2	1.6	2.6	0.8	1.6
Type 2 Diabetes (T2D) (2018)	1.2	2.2	3.5	-1.0	-1.9
Eye problems/disorders: Diabetes related eye disease	1.2	1.3	2.2	-0.6	-1.5
Alcohol usually taken with meals	1.2	2.0	2.8	1.1	1.7
Financial difficulties in last 2 years	1.2	1.7	2.2	1.1	1.5
Eye problems/disorders: None of the above	1.2	1.4	2.2	1.5	0.8
Medication: Seretide 50 evohaler	1.2	1.4	2.3	-1.5	-0.7
Chest pain or discomfort	1.2	1.7	2.9	0.7	1.7
Commuting to job workplace: Car/motor vehicle	1.2	1.4	1.8	1.3	1.0
Pain type(s) experienced in last month: Hip pain	1.2	1.5	2.3	1.5	0.9
Deep venous thrombosis (DVT) (self-reported)	1.2	1.5	2.5	1.6	0.7
Triglycerides	1.1	1.8	2.6	-1.6	-1.0
Blood White Count	1.1	8.2	13.5	1.7	3.7
Supplements: Zinc	1.1	1.2	1.9	0.7	1.4
Had menopause	1.1	1.4	2.2	-0.8	-1.5
Forced expiratory volume in 1-second (FEV1)	1.1	3.6	5.9	-1.2	-2.4
Depression (self-reported)	1.1	1.4	2.2	-1.5	-0.8
Blood clot in the leg (DVT)	1.1	1.4	2.4	1.6	0.7
Body fat percentage	1.1	4.2	5.2	1.8	2.3
Age at first live birth	1.1	1.9	3.0	-1.7	-0.9
Family relationship satisfaction	1.1	1.4	2.0	-0.9	-1.4
Average weekly spirits intake	1.0	1.2	1.9	0.7	1.4
Fed-up feelings	1.0	1.8	2.2	1.2	1.5
Father’s age at death	1.0	1.4	2.0	-0.9	-1.4
Frequency of tiredness / lethargy in last 2 weeks	1.0	1.6	1.6	1.3	1.3
Qualifications: O levels/GCSEs or equivalent	1.0	1.6	1.9	-1.1	-1.4
Seen a psychiatrist for nerves, anxiety, tension or depression	1.0	1.3	2.3	-1.5	-0.5
Medication: Omeprazole	1.0	1.2	1.7	0.9	1.3
Arm fat percentage (left)	1.0	4.0	5.0	1.7	2.2
Back pain experienced in last month	1.0	1.4	1.5	1.1	1.2
Medication: Gliclazide	1.0	1.1	1.2	-1.1	-1.0
Supplements: Fish oil (including cod liver oil)	1.0	1.4	2.3	0.6	1.5
Risk taking	1.0	1.5	2.3	0.9	1.5
Major Depression (MDD)	0.9	1.1	1.8	0.6	1.4
Lung FVC	0.9	4.3	7.1	-1.3	-2.7
Heel bone mineral density (BMD) T-score, automated (right)	0.9	2.1	3.1	1.1	1.8
Illnesses of siblings	0.9	1.2	1.5	-1.0	-1.2
Arm fat percentage (right)	0.9	3.4	4.3	1.6	2.1
Mouth/teeth dental problems: Bleeding gums	0.9	1.1	1.5	0.8	1.2
Hypothyroidism/myxoedema (self-reported)	0.9	1.8	2.2	-1.5	-1.2
Emphysema/chronic bronchitis	0.9	1.0	1.7	1.3	0.6
Medication: Allopurinol	0.9	1.1	1.7	-0.7	-1.3
Reaction Time	0.8	1.6	1.9	-1.4	-1.2
Heel T-Score	0.8	6.6	6.6	2.5	2.6
Other serious medical condition/disability diagnosed by doctor	0.8	1.0	1.1	1.0	1.0
Trunk fat percentage	0.8	3.2	3.8	1.6	1.9
Frequency of tenseness / restlessness in last 2 weeks	0.8	1.3	1.6	1.3	1.0
Tense / ‘highly strung’	0.8	1.3	1.3	1.1	1.2
High blood pressure (siblings)	0.8	1.1	1.2	1.1	1.0
Reason for reducing amount of alcohol drunk: Health precaution	0.8	1.0	1.7	-0.5	-1.3
Neck or shoulder pain in last month	0.8	1.2	1.3	1.0	1.1
Had major operations	0.8	0.9	1.3	0.7	1.1
Number of self-reported non-cancer illnesses	0.8	1.4	1.5	1.1	1.2
Bipolar Disorder or Schizophrenia	0.7	1.8	2.5	-1.6	-1.0
Schizophrenia (2018)	0.7	1.4	2.4	-1.6	-0.7
Breast Cancer	0.7	1.7	3.1	-0.5	-1.8
Blood Red Count	0.7	6.6	7.0	2.5	2.6
Tinnitus: Yes, but not now, but have in the past	0.7	0.8	1.2	0.5	1.1
Pulse wave Arterial Stiffness index	0.7	0.8	0.9	0.9	0.9
Gout (self-reported)	0.7	1.0	1.8	-0.2	-1.4
Number of full brothers	0.7	0.9	1.8	-1.4	0.0
Hypertension (Self-reported)	0.7	1.8	2.3	1.2	1.5
Mouth/teeth dental problems: Mouth ulcers	0.7	1.0	1.3	1.1	0.9
Medication: Blood pressure	0.7	1.3	2.5	0.2	1.6
Ulcerative Colitis (UC)	0.6	1.2	1.8	1.4	0.7
Blood Eosinophil Count	0.6	4.6	5.6	-2.4	-1.9
Hand grip strength (left)	0.6	1.7	2.7	-0.9	-1.6
Vitamin and mineral supplements	0.6	0.8	1.2	-0.7	-1.1
Hand grip strength (right)	0.6	1.6	3.0	-0.5	-1.7
Taking other prescription medications	0.6	1.0	1.5	-1.2	-0.7
Age when periods started (menarche)	0.6	1.5	2.2	0.9	1.5
Diverticular disease/diverticulitis (self-reported)	0.6	0.8	1.4	-0.3	-1.2
Heart attack	0.6	0.8	1.0	1.0	0.8
Hair/balding pattern: Pattern 3	0.6	0.8	1.1	0.7	1.1
Number of live births	0.6	0.8	1.6	1.3	0.2
Pulse rate	0.6	1.1	1.4	0.9	1.2
Happiness	0.6	0.7	0.9	-1.0	-0.7
Mouth/teeth dental problems: Dentures	0.6	1.0	1.7	-1.3	-0.5
Illnesses of mother	0.6	0.8	1.0	0.7	1.0
Medication for cholesterol, blood pressure or diabetes	0.6	1.1	2.0	-1.4	-0.4
Suffer from ‘nerves’	0.6	0.9	1.2	-1.1	-0.8
Medication for cholesterol	0.6	0.9	1.8	-0.3	-1.3
Ever had prostate specific antigen (PSA) test	0.6	0.7	0.7	0.8	0.8
Heart attack/myocardial infarction (self-reported)	0.6	0.8	1.0	1.0	0.8
Body Mass Index (BMI) (2010)	0.5	0.6	1.0	1.0	0.6
Coronary Artery Disease (CAD)	0.5	0.5	0.7	0.6	0.8
Chronotype (morning person)	0.5	1.3	2.4	-1.6	-0.3
Serious illness, injury or assault to yourself	0.5	0.6	1.2	-1.1	0.0
Medication: Simvastatin	0.5	0.7	0.9	0.7	0.9
Medication: Blood pressure	0.5	0.8	1.3	1.1	0.6
Mean time to correctly identify matches	0.5	0.9	1.4	-1.2	-0.6
Heart disease (mother)	0.5	0.6	0.9	-0.9	-0.5
Age at last live birth	0.5	0.8	0.8	-0.9	-0.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.6	1.1	-0.4	1.0
Commuting to job workplace: Walk	0.5	0.5	0.5	0.7	0.7
Number of operations (self-reported)	0.5	0.8	1.5	1.2	-0.1
Verbal and Numeric Reasoning (VNR)	0.4	1.0	1.0	-0.9	-1.0
LDL Cholesterol	0.4	0.7	0.8	0.7	0.9
Cardiovascular Disease	0.4	1.3	1.5	1.0	1.2
Current tobacco smoking	0.4	0.7	1.2	0.4	1.1
Average weekly fortified wine intake	0.4	0.5	0.8	0.9	0.5
Supplements: Glucosamine	0.4	0.5	0.7	0.8	0.4
Medication: Cholesterol lowering	0.4	0.6	1.1	1.1	0.2
Medication: Amlodipine	0.4	0.5	0.9	-1.0	0.3
Worry too long after embarrassment	0.4	0.6	1.0	-0.5	-1.0
Pulse rate, automated reading	0.4	1.3	1.4	1.1	1.2
Mood swings	0.4	0.6	0.9	1.0	0.6
Ever had bowel cancer screening	0.4	0.5	0.9	1.0	0.3
Qualifications: nursing, teaching	0.4	0.7	1.0	-0.5	-1.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.5	0.8	0.9	0.4
Average weekly champagne plus white wine intake	0.4	0.5	1.0	-0.0	-1.0
Guilty feelings	0.4	0.6	0.9	0.9	0.5
Ever taken oral contraceptive pill	0.4	0.5	0.9	0.4	0.9
Illnesses of father: High blood pressure	0.4	0.4	0.9	-0.2	-0.9
Myopia	0.4	0.6	1.0	0.4	-1.0
Bipolar Disorder (2018)	0.3	0.4	0.6	-0.6	-0.8
Schizophrenia vs Biploar Disorder	0.3	0.4	0.5	0.5	0.7
Prostate Cancer	0.3	0.5	0.9	-1.0	-0.3
Medication: Metformin	0.3	0.5	0.8	-0.3	-0.9
Townsend deprivation index at recruitment	0.3	0.4	0.7	-0.8	-0.3
Maternal smoking around birth	0.3	0.4	0.6	-0.5	-0.8
Stomach or abdominal pain in last month	0.3	0.3	0.6	0.3	0.8
Qualifications: None of the above	0.3	0.6	0.9	0.5	1.0
Mouth/teeth dental problems	0.3	0.5	0.7	-0.6	-0.8
Worrier / anxious feelings	0.3	0.6	0.9	0.9	-0.5
Falls in the last year	0.3	0.4	0.5	-0.7	0.4
Breastfed as a baby	0.3	0.3	0.4	-0.7	-0.5
Exposure to tobacco smoke outside home	0.3	0.3	0.4	0.7	0.5
Wheeze or whistling in the chest in last year	0.3	0.6	0.8	-0.6	0.9
Leg pain on walking	0.3	0.4	0.6	0.4	0.8
Loneliness, isolation	0.3	0.4	0.5	0.6	0.7
Mineral and other dietary supplements	0.3	0.4	0.5	-0.5	-0.7
Miserableness	0.3	0.4	0.8	-0.4	-0.9
Wears glasses or contact lenses	0.3	0.3	0.5	0.7	-0.3
Medication: Bendroflumethiazide	0.3	0.5	0.6	0.7	0.8
Diastolic blood pressure, automated reading	0.3	0.8	1.1	1.1	0.7
Basal cell carcinoma (self-reported)	0.3	0.3	0.6	-0.1	-0.8
Heart disease (siblings)	0.3	0.3	0.6	0.3	0.8
Intelligence (Savage-Jansen 2018)	0.2	0.8	1.5	-0.2	-1.2
Alzheimer’s Disease (in mother)	0.2	0.2	0.4	-0.1	0.6
Crohns Disease (2012)	0.2	0.4	0.7	-0.9	0.2
Neuroticism (2016)	0.2	0.4	0.4	-0.6	-0.6
Hypothyroidism (self reported)	0.2	0.6	1.0	-1.0	-0.4
Sensitivity / hurt feelings	0.2	0.3	0.6	0.1	-0.8
Angina	0.2	0.3	0.3	-0.5	-0.6
Severe depression (siblings)	0.2	0.2	0.3	0.2	0.6
Hayfever, allergic rhinitis or eczema	0.2	0.4	0.5	-0.7	-0.5
Waist circumference	0.2	0.9	1.0	1.0	0.8
Ever unenthusiastic/disinterested for a whole week	0.2	0.2	0.4	-0.6	-0.4
Pain all over the body in last month	0.2	0.2	0.3	0.1	0.6
Fluid intelligence score	0.2	0.5	0.8	-0.4	-0.9
Alcohol intake versus 10 years previously	0.2	0.3	0.4	0.4	0.7
Medication: Lansoprazole	0.2	0.2	0.5	-0.7	-0.1
Exposure to tobacco smoke at home	0.2	0.2	0.5	0.1	-0.7
Pulse wave reflection index	0.2	0.2	0.4	0.0	0.6
Birth weight	0.2	0.4	0.9	-0.0	-0.9
Mouth/teeth dental problems: Loose teeth	0.2	0.3	0.5	0.3	0.7
Illness, injury, bereavement, stress in last 2 years	0.2	0.2	0.4	-0.1	-0.6
Medication: Aspirin	0.2	0.3	0.6	0.8	0.1
Smoking status: Current	0.2	0.4	0.6	0.3	0.8
Mother’s age at death	0.2	0.2	0.4	0.0	0.7
Alcohol drinker status: Previous	0.2	0.2	0.3	0.6	-0.2
Depressed Affect (Nagel 2018)	0.1	0.1	0.2	0.3	0.5
Neuroticism (Nagel 2018)	0.1	0.3	0.4	-0.4	-0.7
Worry (Nagel 2018)	0.1	0.2	0.2	-0.3	-0.5
Alzheimer’s Disease (including proxy)	0.1	0.2	0.3	-0.5	0.3
Irritable Bowel Disease (IBD)	0.1	0.2	0.2	-0.4	-0.5
Schizophrenia (2014)	0.1	0.3	0.5	-0.7	0.2
Allergy or Eczema	0.1	0.1	0.3	-0.1	0.5
Respiratory disease	0.1	0.3	0.4	-0.7	0.3
Tanning	0.1	0.8	1.5	-0.3	-1.2
Number of treatments/medications taken	0.1	0.2	0.2	0.5	0.3
Hearing difficulty/problems: Yes	0.1	0.2	0.4	-0.6	-0.2
Relative age of first facial hair	0.1	0.3	0.4	0.4	0.6
Ever used hormone-replacement therapy (HRT)	0.1	0.2	0.3	-0.1	-0.5
Qualifications: CSEs or equivalent	0.1	0.1	0.2	-0.5	-0.0
Multivitamins +/- minerals	0.1	0.1	0.2	-0.1	0.5
Medication: Levothyroxine sodium	0.1	0.1	0.2	-0.4	-0.3
Chronic bronchitis/emphysema (father)	0.1	0.2	0.3	0.0	0.6
High blood pressure (mother)	0.1	0.1	0.2	0.4	-0.3
Body mass index (BMI)	0.1	0.5	0.5	0.7	0.7
Past tobacco smoking	0.1	0.2	0.2	-0.4	0.4
Nervous feelings	0.1	0.1	0.2	-0.5	0.0
Allergy	0.1	0.2	0.3	0.6	-0.1
Diabetes (self-reported)	0.1	0.2	0.2	0.5	-0.3
Hayfever/allergic rhinitis (self-reported)	0.1	0.1	0.2	0.0	-0.5
Seen doctor (GP) for nerves, anxiety, tension or depression	0.1	0.1	0.2	0.1	0.4
Peak expiratory flow (PEF)	0.1	0.3	0.4	0.4	-0.6
Ever highly irritable/argumentative for 2 days	0.1	0.1	0.1	-0.3	-0.2
Headache pain in last month	0.1	0.1	0.2	-0.0	0.5
Angina (self-reported)	0.1	0.1	0.2	-0.3	-0.4
Medication: Ibuprofen	0.1	0.1	0.1	0.1	0.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.1	0.1	0.2	0.4	-0.1
Leg fat mass (right)	0.1	0.2	0.2	0.4	0.5
Alcohol intake frequency.	0.1	0.2	0.3	0.5	0.2
Qualifications: NVQ or HND or HNC or equivalent	0.1	0.1	0.2	0.1	-0.4
Supplements: Vitamin C	0.1	0.1	0.2	0.5	-0.0
Illnesses of siblings: Diabetes	0.1	0.1	0.3	0.5	-0.0
Smoking status: Previous	0.1	0.1	0.2	0.1	-0.5
Average weekly red wine intake	0.1	0.1	0.2	-0.1	-0.4
Diabetes diagnosed by doctor	0.1	0.2	0.2	0.4	-0.4
Medication: Aspirin	0.1	0.1	0.1	0.4	-0.4
Medication: Lisinopril	0.1	0.1	0.1	-0.4	0.3
Ever smoked	0.1	0.2	0.3	0.6	-0.1
Average weekly beer plus cider intake	0.1	0.1	0.1	-0.4	-0.2
Irritability	0.1	0.2	0.3	0.3	0.5
Fractured/broken bones in last 5 years	0.1	0.1	0.1	-0.0	0.4
Commuting to job workplace: Cycle	0.1	0.1	0.2	0.3	-0.4
Leg fat mass (left)	0.1	0.2	0.2	0.4	0.5
Ovarian Cancer	0.0	0.0	0.0	0.2	0.1
Age at First Birth	0.0	0.0	0.0	0.1	-0.0
Bipolar Disorder (2011)	0.0	0.0	0.1	-0.2	0.1
Primary Biliary Cirrhosis	0.0	0.0	0.0	0.1	-0.2
BMI	0.0	0.2	0.2	0.5	-0.4
Smoking Status	0.0	0.0	0.1	-0.3	-0.1
Neuroticism	0.0	0.0	0.0	0.1	-0.0
Hair Pigment	0.0	1.0	1.4	0.7	1.2
Medication: Co-codamol	0.0	0.0	0.1	-0.3	-0.0
Frequency of unenthusiasm / disinterest in last 2 weeks	0.0	0.0	0.0	0.1	0.1
Relative age voice broke	0.0	0.1	0.1	0.1	-0.4
Medication: Atenolol	0.0	0.0	0.0	-0.1	-0.1
Trunk fat mass	0.0	0.0	0.1	0.1	-0.2
Neuroticism score	0.0	0.0	0.1	0.3	0.1
Time employed in main current job	0.0	0.0	0.1	0.1	-0.3
Noisy workplace	0.0	0.0	0.1	0.0	0.3
Medication: Ibuprofen (e.g. Nurofen)	0.0	0.1	0.1	0.3	0.2
Lung cancer (father)	0.0	0.0	0.0	0.2	0.0
Arm fat mass (right)	0.0	0.0	0.0	-0.1	-0.1
Length of working week for main job	0.0	0.1	0.1	0.2	-0.2
Glaucoma (self-reported)	0.0	0.0	0.0	0.1	-0.1
Comparative body size at age 10	0.0	0.0	0.1	0.3	0.2
Number of children fathered	0.0	0.0	0.0	0.2	0.1
Health satisfaction	0.0	0.0	0.1	-0.2	-0.2
Whole body fat mass	0.0	0.1	0.1	0.4	0.2
Number of full sisters	0.0	0.0	0.1	-0.3	0.1
Eye problems/disorders: Cataract	0.0	0.0	0.0	-0.2	0.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.0	0.0	0.1	0.2	-0.1
Arm fat mass (left)	0.0	0.0	0.0	0.1	-0.0
Hearing aid user	0.0	0.0	0.0	0.1	0.1
Eye problems/disorders: Glaucoma	0.0	0.0	0.1	-0.2	-0.1
Alcohol drinker status: Never	0.0	0.0	0.0	-0.0	-0.2
Ever depressed for a whole week	0.0	0.0	0.0	-0.2	-0.1

Hub : Genes

C2CD4A

Models

Trait associations