Best TWAS P=2.18e-11 · Best GWAS P=2.95e-15 conditioned to 0.00739
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adrenal Gland | DYM | 0.30 | 0.01 | enet | 15 | 0.01 | 1.2e-01 | 7.6 | 6.7 | 2.2e-11 | 0.80 | 0.03 | 0.81 | TRUE |
| 2 | GTEx | Esophagus Mucosa | DYM | 0.12 | 0.01 | enet | 12 | 0.04 | 1.0e-03 | 7.6 | 5.4 | 6.9e-08 | 0.67 | 0.02 | 0.94 | FALSE |
| 3 | YFS | Blood | DYM | 0.05 | 0.05 | lasso | 4 | 0.04 | 1.5e-13 | -4.3 | 5.7 | 1.1e-08 | 0.74 | 0.99 | 0.01 | FALSE |
| 4 | The Cancer Genome Atlas | Colon Adenocarcinoma | C18orf32 | 0.05 | 0.05 | lasso | 5 | 0.04 | 3.5e-03 | -5.3 | 5.2 | 1.8e-07 | 0.41 | 0.04 | 0.26 | FALSE |
| 5 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | C18orf32 | 0.04 | 0.03 | blup | 48 | 0.04 | 6.5e-05 | 4.7 | 6.6 | 4.6e-11 | 0.57 | 0.00 | 0.99 | TRUE |