[Hub]/) : Traits : Arm predicted mass (left) : ← →

chr19:3,652,410-5,153,606

Best TWAS P=1.72e-12 · Best GWAS P=1.05e-08 conditioned to 0.471

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	UBXN6	0.27	0.25	enet	28	0.29	4.6e-36	4.870	-5.9	3.4e-09	-0.92	0.07	0.93	FALSE
2	GTEx	Adipose Visceral Omentum	CHAF1A	0.24	0.26	lasso	3	0.26	6.2e-14	5.411	-5.2	1.5e-07	-0.94	0.01	0.99	FALSE
3	GTEx	Adrenal Gland	CHAF1A	0.22	0.18	lasso	3	0.17	1.1e-06	4.830	-5.2	2.6e-07	-0.90	0.02	0.97	FALSE
4	GTEx	Artery Aorta	UBXN6	0.13	0.02	lasso	5	0.03	5.7e-03	-5.235	-6.4	2.0e-10	-0.79	0.02	0.95	FALSE
5	GTEx	Artery Aorta	CTB-50L17.5	0.16	0.15	lasso	7	0.15	1.0e-08	5.650	-5.5	3.3e-08	-0.89	0.01	0.99	FALSE
6	GTEx	Artery Coronary	CTB-50L17.9	0.43	0.14	lasso	6	0.12	6.5e-05	5.005	-5.4	6.3e-08	-0.78	0.06	0.73	FALSE
7	GTEx	Artery Tibial	UBXN6	0.18	0.07	lasso	3	0.14	6.3e-11	5.723	-6.4	1.2e-10	-0.89	0.01	0.99	FALSE
8	GTEx	Brain Caudate basal ganglia	CTB-50L17.9	0.27	0.25	lasso	2	0.24	1.8e-07	5.650	-5.6	2.2e-08	-0.86	0.01	0.97	FALSE
9	GTEx	Brain Cerebellar Hemisphere	CHAF1A	0.62	0.40	lasso	8	0.36	3.5e-10	5.650	-5.6	2.2e-08	-0.89	0.01	0.99	FALSE
10	GTEx	Brain Cerebellum	CHAF1A	0.51	0.35	lasso	4	0.34	9.7e-11	5.650	-5.6	2.4e-08	-0.91	0.01	0.99	FALSE
11	GTEx	Brain Cerebellum	CTB-50L17.9	0.53	0.41	lasso	2	0.50	3.6e-17	5.005	-5.7	1.4e-08	-0.86	0.02	0.98	FALSE
12	GTEx	Brain Frontal Cortex BA9	UBXN6	0.31	0.06	enet	5	0.12	3.5e-04	5.005	-5.4	5.9e-08	-0.85	0.02	0.88	FALSE
13	GTEx	Brain Frontal Cortex BA9	CTB-50L17.9	0.27	0.21	lasso	3	0.19	7.9e-06	5.005	-5.6	2.5e-08	-0.86	0.03	0.95	FALSE
14	GTEx	Brain Frontal Cortex BA9	AC007292.6	0.35	0.01	lasso	6	0.12	3.6e-04	-0.016	-5.2	2.5e-07	-0.53	0.04	0.52	FALSE
15	GTEx	Brain Nucleus accumbens basal ganglia	CHAF1A	0.31	0.28	lasso	2	0.24	4.0e-07	5.411	-5.4	6.6e-08	-0.92	0.02	0.97	FALSE
16	GTEx	Brain Nucleus accumbens basal ganglia	CTB-50L17.9	0.45	0.25	lasso	8	0.23	8.6e-07	5.650	-6.2	4.2e-10	-0.80	0.02	0.97	FALSE
17	GTEx	Brain Putamen basal ganglia	CHAF1A	0.40	0.34	lasso	4	0.37	1.2e-09	5.650	-5.1	2.8e-07	-0.85	0.01	0.98	FALSE
18	GTEx	Breast Mammary Tissue (Female)	CHAF1A	0.33	0.14	lasso	6	0.09	1.6e-03	5.411	-5.2	1.7e-07	-0.91	0.03	0.92	FALSE
19	GTEx	Cells Transformed fibroblasts	UBXN6	0.09	0.10	lasso	1	0.08	1.5e-06	-5.235	-5.2	1.7e-07	-0.44	0.05	0.94	FALSE
20	GTEx	Colon Sigmoid	UBXN6	0.34	0.15	lasso	6	0.14	1.7e-05	5.005	-5.8	7.4e-09	-0.85	0.03	0.95	FALSE
21	GTEx	Esophagus Muscularis	UBXN6	0.35	0.24	enet	20	0.29	3.7e-18	5.005	-5.4	6.0e-08	-0.88	0.02	0.98	FALSE
22	GTEx	Heart Atrial Appendage	UBXN6	0.34	0.12	lasso	6	0.21	6.5e-10	5.650	-6.2	7.4e-10	-0.76	0.02	0.98	FALSE
23	GTEx	Heart Atrial Appendage	CTB-50L17.9	0.32	0.34	lasso	3	0.34	3.8e-16	5.005	-5.2	1.8e-07	-0.83	0.16	0.84	FALSE
24	GTEx	Heart Left Ventricle	CHAF1A	0.17	0.12	lasso	2	0.11	1.9e-06	5.650	-5.7	1.5e-08	-0.88	0.01	0.99	FALSE
25	GTEx	Heart Left Ventricle	UBXN6	0.21	0.14	lasso	6	0.16	5.6e-09	-5.301	-6.0	1.4e-09	-0.65	0.03	0.97	FALSE
26	GTEx	Muscle Skeletal	CHAF1A	0.18	0.21	lasso	2	0.20	9.7e-20	5.650	-5.6	1.9e-08	-0.90	0.01	0.99	FALSE
27	GTEx	Muscle Skeletal	UBXN6	0.19	0.14	lasso	5	0.18	4.1e-17	-5.318	-6.4	1.9e-10	-0.70	0.05	0.95	FALSE
28	GTEx	Nerve Tibial	UBXN6	0.17	0.08	enet	20	0.09	4.4e-07	5.148	-5.6	2.6e-08	-0.87	0.03	0.97	FALSE
29	GTEx	Nerve Tibial	CTB-50L17.5	0.11	0.08	enet	4	0.08	1.6e-06	5.411	-5.5	3.5e-08	-0.91	0.02	0.98	FALSE
30	GTEx	Ovary	CTB-50L17.9	0.29	0.24	lasso	2	0.21	6.5e-06	5.148	-5.1	3.0e-07	-0.82	0.04	0.90	FALSE
31	GTEx	Skin Not Sun Exposed Suprapubic	AC007292.6	0.11	0.08	lasso	6	0.07	7.8e-05	5.723	-5.4	5.9e-08	-0.98	0.02	0.96	FALSE
32	GTEx	Skin Sun Exposed Lower leg	CHAF1A	0.19	0.18	lasso	1	0.17	5.1e-14	5.411	-5.4	6.3e-08	-0.92	0.02	0.98	FALSE
33	GTEx	Stomach	AC007292.4	0.27	0.09	lasso	5	0.04	4.0e-03	-5.591	5.8	7.9e-09	0.49	0.01	0.91	FALSE
34	GTEx	Testis	CHAF1A	0.18	0.09	lasso	2	0.07	4.0e-04	5.650	-5.4	7.9e-08	-0.85	0.01	0.91	FALSE
35	GTEx	Testis	UBXN6	0.20	0.10	lasso	3	0.10	2.9e-05	5.005	-5.2	1.9e-07	-0.89	0.04	0.96	FALSE
36	GTEx	Testis	CTB-50L17.9	0.39	0.30	enet	36	0.34	9.4e-16	5.005	-5.8	7.4e-09	-0.78	0.08	0.92	FALSE
37	GTEx	Thyroid	UBXN6	0.25	0.19	lasso	5	0.23	8.8e-18	5.723	-5.6	2.0e-08	-0.96	0.01	0.99	FALSE
38	GTEx	Vagina	CTB-50L17.9	0.38	0.26	lasso	5	0.23	5.7e-06	5.650	-5.7	1.2e-08	-0.87	0.02	0.95	FALSE
39	The Cancer Genome Atlas	Breast Invasive Carcinoma	UBXN6	0.03	0.03	lasso	3	0.03	2.3e-06	-5.235	-5.5	2.9e-08	-0.48	0.02	0.97	FALSE
40	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	UBXN6	0.05	0.01	blup	57	0.04	6.6e-05	5.650	-7.1	1.7e-12	-0.74	0.01	0.97	TRUE
41	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CHAF1A	0.12	0.11	lasso	3	0.12	7.9e-13	5.411	-5.7	1.5e-08	-0.95	0.02	0.98	FALSE
42	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	MPND	0.05	0.03	lasso	3	0.02	5.3e-03	5.202	5.2	2.5e-07	0.85	0.04	0.65	FALSE
43	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	UBXN6	0.18	0.17	enet	18	0.18	9.9e-20	5.650	-5.5	3.4e-08	-0.87	0.01	0.99	FALSE
44	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	CHAF1A	0.15	0.12	lasso	2	0.12	3.2e-07	5.411	-5.4	5.4e-08	-0.91	0.04	0.96	FALSE
45	The Cancer Genome Atlas	Lung Adenocarcinoma	CHAF1A	0.05	0.04	lasso	4	0.03	2.3e-04	5.650	-5.3	1.4e-07	-0.88	0.01	0.97	FALSE
46	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	UBXN6	0.04	0.03	lasso	2	0.02	1.6e-03	5.005	-5.5	4.8e-08	-0.88	0.01	0.81	FALSE
47	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	CHAF1A	0.20	0.11	lasso	2	0.11	5.6e-05	5.723	-5.9	4.3e-09	-0.98	0.01	0.97	FALSE
48	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	UBXN6	0.23	0.11	lasso	5	0.12	2.5e-05	5.005	-5.8	6.1e-09	-0.90	0.02	0.64	FALSE
49	The Cancer Genome Atlas	Prostate Adenocarcinoma	UBXN6	0.13	0.10	lasso	2	0.10	1.3e-10	5.650	-6.0	2.7e-09	-0.87	0.00	1.00	FALSE
50	The Cancer Genome Atlas	Thyroid Carcinoma	UBXN6	0.16	0.12	lasso	2	0.12	5.4e-12	5.650	-5.9	4.1e-09	-0.86	0.00	1.00	FALSE