Best TWAS P=7.16e-08 · Best GWAS P=3.17e-07 conditioned to 0.000506
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Artery Tibial | HMGB1P31 | 0.17 | 0.00 | enet | 21 | 0.06 | 1.8e-05 | -4.5 | -5.1 | 2.9e-07 | 0.19 | 0.07 | 0.47 | FALSE |
2 | GTEx | Testis | HMGB1P31 | 0.17 | 0.01 | enet | 21 | 0.02 | 4.6e-02 | -4.0 | -5.4 | 7.2e-08 | 0.34 | 0.17 | 0.23 | TRUE |