[Hub]/) : Traits : Arm predicted mass (left) : ← →

chr2:241,563,169-243,048,760

Best TWAS P=3.22e-09 · Best GWAS P=1.88e-08 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	SEPT2	0.45	0.36	enet	32	0.43	3.0e-38	4.5	5.6	2.4e-08	-0.08	0.36	0.62	FALSE
2	GTEx	Adipose Subcutaneous	AC005104.3	0.12	0.03	lasso	5	0.06	1.5e-05	4.5	5.5	3.1e-08	-0.06	0.29	0.44	FALSE
3	GTEx	Adipose Visceral Omentum	BOK	0.20	0.12	lasso	4	0.12	1.4e-06	-5.6	-5.9	3.2e-09	0.97	0.00	1.00	TRUE
4	GTEx	Brain Frontal Cortex BA9	SEPT2	0.30	-0.01	enet	32	0.02	1.1e-01	4.5	5.5	3.6e-08	-0.13	0.07	0.09	FALSE
5	GTEx	Breast Mammary Tissue	SEPT2	0.46	0.33	enet	37	0.35	5.2e-19	4.5	5.3	1.2e-07	-0.08	0.36	0.62	FALSE
6	GTEx	Cells Transformed fibroblasts	SEPT2	0.34	0.14	lasso	6	0.32	5.5e-25	4.5	5.3	1.4e-07	-0.09	0.36	0.62	FALSE
7	GTEx	Esophagus Gastroesophageal Junction	SEPT2	0.66	0.38	enet	29	0.50	7.1e-21	4.5	5.5	2.8e-08	-0.08	0.36	0.62	FALSE
8	GTEx	Esophagus Mucosa	SEPT2	0.59	0.50	enet	37	0.56	2.7e-44	4.5	5.4	7.9e-08	-0.06	0.36	0.62	FALSE
9	GTEx	Esophagus Muscularis	SEPT2	0.57	0.34	enet	34	0.48	1.7e-32	4.5	5.2	1.9e-07	-0.11	0.37	0.61	FALSE
10	GTEx	Heart Atrial Appendage	AC114730.11	0.16	0.07	enet	11	0.16	1.2e-07	-3.2	-5.5	3.1e-08	0.28	0.26	0.29	FALSE
11	GTEx	Muscle Skeletal	SEPT2	0.39	0.22	enet	46	0.26	1.0e-25	4.5	5.3	1.4e-07	-0.13	0.36	0.62	FALSE
12	GTEx	Nerve Tibial	AC005104.3	0.28	0.21	enet	19	0.24	4.6e-17	4.5	5.1	2.8e-07	-0.06	0.37	0.61	FALSE
13	GTEx	Ovary	SEPT2	0.56	0.29	lasso	5	0.23	2.4e-06	4.5	5.2	1.8e-07	-0.06	0.26	0.43	FALSE
14	GTEx	Skin Not Sun Exposed Suprapubic	SEPT2	0.63	0.38	enet	29	0.42	1.1e-24	4.5	5.5	4.9e-08	-0.08	0.36	0.62	FALSE
15	GTEx	Skin Not Sun Exposed Suprapubic	AC005104.3	0.27	0.06	enet	24	0.20	5.6e-11	3.6	5.9	4.6e-09	-0.21	0.46	0.21	FALSE
16	METSIM	Adipose	BOK	0.06	0.03	lasso	6	0.03	7.8e-06	-5.6	-5.4	6.4e-08	0.95	0.00	1.00	FALSE
17	NTR	Blood	SEPT2	0.18	0.10	enet	34	0.14	1.0e-43	4.5	5.7	1.4e-08	-0.13	0.37	0.62	TRUE
18	The Cancer Genome Atlas	Lung Adenocarcinoma	SEPT2	0.24	0.04	blup	45	0.08	1.6e-09	2.6	5.1	2.9e-07	-0.12	0.00	0.02	FALSE