Best TWAS P=3.4e-10 · Best GWAS P=4.85e-12 conditioned to 0.000521
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Breast Invasive Carcinoma | IBSP | 0.05 | 0.05 | lasso | 6 | 0.07 | 1.2e-13 | -6.8 | 6.0 | 1.9e-09 | -0.79 | 0.00 | 1.00 | FALSE |
| 2 | The Cancer Genome Atlas | Colon Adenocarcinoma | IBSP | 0.09 | 0.02 | enet | 15 | 0.07 | 9.4e-05 | -2.0 | 5.4 | 5.7e-08 | -0.62 | 0.02 | 0.62 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | IBSP | 0.08 | 0.00 | blup | 77 | 0.00 | 1.6e-01 | -4.9 | 6.3 | 3.4e-10 | -0.71 | 0.02 | 0.63 | TRUE |
| 4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | IBSP | 0.06 | 0.01 | blup | 78 | 0.03 | 8.2e-05 | -5.0 | 5.2 | 2.3e-07 | -0.55 | 0.02 | 0.87 | FALSE |
| 5 | The Cancer Genome Atlas | Lung Adenocarcinoma | IBSP | 0.06 | 0.01 | blup | 78 | 0.03 | 7.7e-05 | -6.8 | 6.1 | 1.3e-09 | -0.75 | 0.00 | 0.99 | FALSE |