[Hub]/) : Traits : Arm predicted mass (left) :

chr4:86,236,934-88,430,396

Best TWAS P=1.24e-10 · Best GWAS P=5.23e-10 conditioned to 0.0315

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex PTPN13 0.13 0.18 bslmm 418 0.18 6.8e-22 5.5 -5.8 7.2e-09 -0.44 0.28 0.72 FALSE
2 GTEx Artery Aorta MAPK10 0.15 0.17 enet 16 0.17 1.4e-09 5.8 -5.8 6.1e-09 -0.81 0.01 0.99 FALSE
3 GTEx Brain Caudate basal ganglia PTPN13 0.26 0.16 enet 17 0.11 4.6e-04 5.4 -5.1 3.0e-07 -0.34 0.17 0.61 FALSE
4 GTEx Colon Sigmoid MAPK10 0.25 0.11 lasso 8 0.07 1.6e-03 5.9 -6.4 1.2e-10 -0.74 0.02 0.95 TRUE
5 GTEx Thyroid PTPN13 0.41 0.31 lasso 6 0.30 3.2e-23 6.0 5.9 4.8e-09 0.81 0.01 0.99 FALSE
6 ROSMAP Brain Pre-frontal Cortex PTPN13 0.09 0.03 blup 409 0.07 4.7e-09 5.5 -5.7 1.3e-08 -0.45 0.25 0.75 FALSE