Best TWAS P=6.95e-11 · Best GWAS P=7.27e-10 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | YFS | Blood | DAB2 | 0.20 | 0.20 | lasso | 14 | 0.21 | 3e-67 | 6.1 | -6.5 | 7.0e-11 | -0.98 | 0.01 | 0.99 | TRUE |
2 | The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | DAB2 | 0.18 | -0.01 | blup | 83 | 0.05 | 2e-02 | 1.9 | -5.5 | 4.1e-08 | -0.60 | 0.02 | 0.20 | FALSE |