Best TWAS P=7.71e-10 · Best GWAS P=4.49e-13 conditioned to 3.08e-06
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | WDR70 | 0.06 | 0.03 | lasso | 8 | 0.03 | 3.5e-03 | -5.1 | 5.5 | 3.0e-08 | -0.72 | 0.31 | 0.53 | FALSE |
| 2 | GTEx | Esophagus Muscularis | LMBRD2 | 0.13 | 0.07 | enet | 21 | 0.08 | 1.8e-05 | 3.4 | -5.5 | 3.6e-08 | -0.04 | 0.12 | 0.07 | TRUE |
| 3 | GTEx | Whole Blood | C5orf42 | 0.07 | 0.00 | enet | 16 | 0.01 | 1.8e-02 | -7.2 | 5.2 | 1.8e-07 | -0.68 | 0.01 | 0.88 | FALSE |
| 4 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | C5orf42 | 0.04 | 0.05 | lasso | 3 | 0.04 | 1.1e-03 | -6.4 | 6.2 | 7.7e-10 | -0.92 | 0.01 | 0.76 | TRUE |