Best TWAS P=3.23e-16 · Best GWAS P=1.99e-18 conditioned to 0.0011
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | ROSMAP | Brain Pre-frontal Cortex | CTC-498M16.2 | 0.11 | 0.13 | lasso | 6 | 0.12 | 1.2e-14 | -8.6 | -8.2 | 3.2e-16 | 0.89 | 0.01 | 0.99 | TRUE |
2 | YFS | Blood | MEF2C | 0.16 | 0.09 | enet | 28 | 0.12 | 5.1e-36 | -5.4 | 5.4 | 8.3e-08 | -0.41 | 1.00 | 0.00 | FALSE |