Best TWAS P=2.51e-08 · Best GWAS P=3.22e-09 conditioned to 0.106
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | RP11-486G15.2 | 0.18 | 0.05 | lasso | 5 | 0.08 | 7.2e-07 | 3.3 | 5.3 | 1.4e-07 | -0.73 | 0.08 | 0.91 | TRUE |
| 2 | GTEx | Cells Transformed fibroblasts | TTLL7 | 0.11 | 0.01 | enet | 13 | 0.01 | 3.1e-02 | -5.1 | -5.6 | 2.5e-08 | 0.50 | 0.28 | 0.68 | TRUE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | TTLL7 | 0.10 | 0.10 | lasso | 8 | 0.09 | 4.3e-12 | -5.3 | 5.4 | 7.3e-08 | -0.55 | 0.21 | 0.79 | FALSE |