Best TWAS P=3.35e-10 · Best GWAS P=1.03e-08 conditioned to 0.0148
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | CTD-3076O17.1 | 0.22 | 0.05 | lasso | 6 | 0.04 | 2.9e-04 | -3.7 | -5.5 | 3.4e-08 | 0.49 | 0.16 | 0.80 | FALSE |
| 2 | GTEx | Adipose Visceral Omentum | CTD-3076O17.1 | 0.21 | 0.00 | lasso | 6 | 0.00 | 6.2e-01 | -5.0 | -6.3 | 3.3e-10 | 0.60 | 0.04 | 0.66 | TRUE |
| 3 | GTEx | Heart Atrial Appendage | ADAMTS17 | 0.22 | 0.00 | lasso | 4 | 0.09 | 9.6e-05 | -4.1 | -6.1 | 9.3e-10 | 0.38 | 0.10 | 0.23 | FALSE |
| 4 | GTEx | Testis | CTD-3076O17.1 | 0.45 | 0.17 | enet | 19 | 0.14 | 1.0e-06 | -5.0 | -5.8 | 5.6e-09 | 0.74 | 0.04 | 0.95 | FALSE |