Best TWAS P=2.32e-08 · Best GWAS P=2.87e-07 conditioned to 0.000695
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ROSMAP | Brain Pre-frontal Cortex | GSTM1 | 0.51 | 0.05 | blup | 434 | 0.26 | 1.4e-33 | -1.1 | 5.6 | 2.3e-08 | 0.35 | 0.73 | 0.03 | TRUE |
| 2 | The Cancer Genome Atlas | Brain Lower Grade Glioma | GSTM2 | 0.09 | 0.01 | blup | 38 | 0.06 | 3.8e-07 | -2.6 | 5.2 | 1.9e-07 | 0.36 | 0.01 | 0.03 | FALSE |