Best TWAS P=1.58e-07 · Best GWAS P=1.11e-07 conditioned to 0.000235
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Breast Invasive Carcinoma | TTC38 | 0.07 | 0.02 | lasso | 7 | 0.07 | 2.6e-14 | 4.7 | -5.2 | 1.6e-07 | -0.36 | 0.01 | 0.97 | TRUE |
2 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | TTC38 | 0.12 | 0.09 | enet | 17 | 0.13 | 6.0e-15 | -2.6 | -5.2 | 1.7e-07 | -0.31 | 0.40 | 0.04 | FALSE |