Best TWAS P=3.65e-08 · Best GWAS P=4.33e-08 conditioned to 0.06
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Nerve Tibial | CTNNB1 | 0.05 | 0.00 | enet | 4 | 0.00 | 2.0e-01 | 5.3 | 5.5 | 4.6e-08 | 0.98 | 0.03 | 0.82 | FALSE |
2 | NTR | Blood | CTNNB1 | 0.04 | 0.04 | lasso | 6 | 0.04 | 4.6e-13 | 5.3 | -5.5 | 3.7e-08 | -0.78 | 0.02 | 0.98 | TRUE |