[Hub]/) : Traits : Trunk fat percentage : ← →

chr4:55,517,005-57,110,821

Best TWAS P=3.5e-12 · Best GWAS P=3.44e-13 conditioned to 0.00244

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	TMEM165	0.22	0.20	enet	47	0.26	1.7e-31	5.7	-6.3	3.1e-10	-0.76	0.22	0.78	FALSE
2	GTEx	Adipose Subcutaneous	TMEM165	0.09	0.01	lasso	3	0.03	1.6e-03	6.6	-6.9	5.5e-12	-0.76	0.20	0.78	FALSE
3	GTEx	Artery Aorta	SRD5A3	0.34	0.05	lasso	12	0.23	1.0e-12	4.8	6.0	2.4e-09	0.49	0.31	0.64	FALSE
4	GTEx	Artery Aorta	TMEM165	0.10	0.00	lasso	3	0.00	7.5e-01	4.8	-5.7	1.4e-08	-0.59	0.06	0.46	FALSE
5	GTEx	Artery Tibial	TMEM165	0.07	0.02	lasso	5	0.01	3.2e-02	-4.3	-6.1	1.4e-09	-0.67	0.26	0.39	FALSE
6	GTEx	Brain Cortex	TMEM165	0.31	0.08	lasso	6	0.04	2.2e-02	5.9	-6.4	1.2e-10	-0.59	0.08	0.40	FALSE
7	GTEx	Breast Mammary Tissue	TMEM165	0.10	0.12	lasso	5	0.12	6.4e-07	5.9	-5.7	1.2e-08	-0.58	0.28	0.64	FALSE
8	GTEx	Breast Mammary Tissue (Male)	TMEM165	0.18	0.11	lasso	10	0.11	1.4e-03	5.9	-5.9	4.2e-09	-0.57	0.08	0.53	FALSE
9	GTEx	Cells EBV-transformed lymphocytes	SRD5A3	0.19	0.06	enet	21	0.13	5.9e-05	5.9	6.2	4.3e-10	0.64	0.17	0.60	FALSE
10	GTEx	Cells EBV-transformed lymphocytes	SRD5A3-AS1	0.21	0.09	lasso	3	0.20	4.3e-07	5.9	5.7	1.1e-08	0.57	0.21	0.61	FALSE
11	GTEx	Cells Transformed fibroblasts	SRD5A3	0.39	0.22	enet	51	0.36	2.9e-28	5.4	6.0	1.8e-09	0.52	0.79	0.21	FALSE
12	GTEx	Cells Transformed fibroblasts	SRD5A3-AS1	0.36	0.19	enet	52	0.30	1.2e-22	5.4	6.3	3.9e-10	0.57	0.49	0.51	FALSE
13	GTEx	Colon Sigmoid	SRD5A3	0.34	0.18	enet	30	0.31	1.5e-11	5.4	5.8	6.9e-09	0.49	0.20	0.77	FALSE
14	GTEx	Colon Sigmoid	SRD5A3-AS1	0.16	0.14	enet	18	0.13	2.9e-05	6.6	6.8	1.1e-11	0.64	0.13	0.68	FALSE
15	GTEx	Esophagus Gastroesophageal Junction	SRD5A3-AS1	0.19	0.12	lasso	3	0.14	9.3e-06	3.6	5.2	2.4e-07	0.53	0.17	0.38	FALSE
16	GTEx	Esophagus Mucosa	SRD5A3	0.20	0.12	enet	24	0.18	2.5e-12	5.4	5.6	2.6e-08	0.46	0.48	0.52	FALSE
17	GTEx	Esophagus Mucosa	CLOCK	0.12	0.11	enet	22	0.09	9.3e-07	5.4	5.4	5.3e-08	0.69	0.32	0.67	FALSE
18	GTEx	Esophagus Mucosa	SRD5A3-AS1	0.18	0.12	enet	26	0.17	1.1e-11	5.4	5.6	2.6e-08	0.47	0.45	0.55	FALSE
19	GTEx	Esophagus Muscularis	SRD5A3	0.34	0.08	enet	30	0.25	1.6e-15	6.3	5.1	2.6e-07	0.37	0.33	0.64	FALSE
20	GTEx	Esophagus Muscularis	CLOCK	0.11	0.00	enet	11	0.01	5.2e-02	-4.6	5.2	1.8e-07	0.60	0.08	0.24	FALSE
21	GTEx	Esophagus Muscularis	SRD5A3-AS1	0.15	0.04	enet	28	0.12	1.8e-07	5.0	5.3	8.9e-08	0.39	0.26	0.45	FALSE
22	GTEx	Lung	SRD5A3	0.35	0.13	enet	32	0.27	1.1e-20	6.4	5.6	2.2e-08	0.43	0.27	0.73	FALSE
23	GTEx	Lung	TMEM165	0.09	0.01	lasso	6	0.01	3.4e-02	5.7	-6.0	1.9e-09	-0.66	0.03	0.86	FALSE
24	GTEx	Lung	SRD5A3-AS1	0.19	0.07	enet	26	0.14	8.6e-11	5.9	6.3	2.8e-10	0.50	0.27	0.73	FALSE
25	GTEx	Muscle Skeletal	SRD5A3-AS1	0.20	0.13	enet	25	0.20	1.4e-19	5.4	5.8	6.6e-09	0.54	0.59	0.41	FALSE
26	GTEx	Nerve Tibial	TMEM165	0.18	0.22	enet	29	0.27	1.6e-19	5.7	-6.3	3.4e-10	-0.62	0.26	0.74	FALSE
27	GTEx	Nerve Tibial	CLOCK	0.14	0.06	lasso	4	0.10	1.6e-07	4.8	6.0	1.7e-09	0.71	0.25	0.74	FALSE
28	GTEx	Prostate	SRD5A3	0.39	0.04	enet	27	0.28	9.6e-08	5.4	5.1	2.8e-07	0.44	0.27	0.37	FALSE
29	GTEx	Prostate	SRD5A3-AS1	0.32	0.14	enet	41	0.22	3.1e-06	5.4	5.6	2.6e-08	0.50	0.14	0.43	FALSE
30	GTEx	Skin Not Sun Exposed Suprapubic	CLOCK	0.08	0.08	lasso	5	0.05	1.4e-03	6.6	6.6	4.8e-11	0.71	0.13	0.72	FALSE
31	GTEx	Skin Not Sun Exposed Suprapubic	SRD5A3-AS1	0.40	0.05	enet	39	0.29	2.1e-16	5.7	5.3	1.4e-07	0.32	0.35	0.64	FALSE
32	GTEx	Skin Sun Exposed Lower leg	CLOCK	0.07	0.05	lasso	5	0.07	3.5e-06	-4.7	5.8	5.5e-09	0.70	0.72	0.24	FALSE
33	GTEx	Small Intestine Terminal Ileum	SRD5A3	0.38	0.28	lasso	4	0.25	2.2e-06	5.9	5.9	3.0e-09	0.56	0.17	0.25	FALSE
34	GTEx	Small Intestine Terminal Ileum	SRD5A3-AS1	0.40	0.32	lasso	3	0.28	4.5e-07	5.9	5.9	3.4e-09	0.57	0.21	0.28	FALSE
35	GTEx	Spleen	TMEM165	0.17	0.13	enet	10	0.11	7.7e-04	5.9	-6.3	2.8e-10	-0.64	0.10	0.33	FALSE
36	GTEx	Stomach	SRD5A3-AS1	0.16	0.11	lasso	11	0.12	1.8e-06	5.4	5.3	1.5e-07	0.58	0.66	0.29	FALSE
37	GTEx	Thyroid	SRD5A3	0.45	0.06	enet	53	0.28	8.5e-22	5.4	5.2	1.9e-07	0.42	0.76	0.24	FALSE
38	GTEx	Thyroid	TMEM165	0.10	0.03	lasso	5	0.03	1.9e-03	5.7	-5.5	4.6e-08	-0.58	0.09	0.86	FALSE
39	GTEx	Thyroid	SRD5A3-AS1	0.32	0.14	enet	56	0.21	1.1e-15	5.7	6.0	2.2e-09	0.54	0.52	0.48	FALSE
40	GTEx	Whole Blood	SRD5A3	0.37	0.19	enet	57	0.30	1.3e-27	5.4	5.7	9.0e-09	0.50	0.75	0.25	FALSE
41	GTEx	Whole Blood	SRD5A3-AS1	0.33	0.17	lasso	9	0.21	4.1e-19	5.4	5.9	3.1e-09	0.55	0.75	0.25	FALSE
42	METSIM	Adipose	TMEM165	0.07	0.07	enet	12	0.07	1.1e-10	6.6	-6.5	5.9e-11	-0.70	0.15	0.85	FALSE
43	NTR	Blood	CLOCK	0.02	0.01	lasso	2	0.01	5.4e-05	5.9	6.2	6.3e-10	0.62	0.23	0.75	FALSE
44	ROSMAP	Brain Pre-frontal Cortex	TMEM165	0.09	0.07	blup	404	0.08	4.9e-11	5.7	-6.6	4.3e-11	-0.67	0.92	0.08	FALSE
45	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	SRD5A3	0.18	0.08	blup	44	0.09	1.0e-07	6.6	5.1	2.7e-07	0.48	0.17	0.83	FALSE
46	The Cancer Genome Atlas	Breast Invasive Carcinoma	TMEM165	0.02	0.04	lasso	3	0.03	1.0e-07	6.6	-7.0	3.5e-12	-0.77	0.07	0.93	TRUE
47	The Cancer Genome Atlas	Colon Adenocarcinoma	TMEM165	0.06	0.07	enet	11	0.06	2.1e-04	6.6	-6.1	1.2e-09	-0.62	0.10	0.66	FALSE
48	The Cancer Genome Atlas	Brain Lower Grade Glioma	TMEM165	0.19	0.16	lasso	4	0.17	2.1e-18	6.6	-6.3	3.3e-10	-0.65	0.10	0.90	FALSE
49	The Cancer Genome Atlas	Lung Adenocarcinoma	SRD5A3	0.04	0.03	lasso	4	0.02	1.0e-03	5.4	5.7	9.1e-09	0.67	0.06	0.79	FALSE
50	The Cancer Genome Atlas	Lung Adenocarcinoma	TMEM165	0.03	0.01	blup	55	0.02	1.4e-03	6.6	-6.1	1.2e-09	-0.67	0.04	0.83	FALSE
51	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	SRD5A3	0.03	0.03	enet	4	0.05	3.1e-06	-6.4	6.9	4.7e-12	0.80	0.02	0.95	FALSE
52	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	SRD5A3	0.26	0.12	lasso	6	0.10	7.0e-05	5.4	5.2	2.5e-07	0.56	0.20	0.44	FALSE
53	The Cancer Genome Atlas	Prostate Adenocarcinoma	TMEM165	0.05	0.06	enet	5	0.05	4.3e-06	6.6	-5.8	7.9e-09	-0.56	0.13	0.85	FALSE
54	The Cancer Genome Atlas	Stomach Adenocarcinoma	CLOCK	0.08	0.07	enet	9	0.06	4.5e-05	5.3	5.2	2.6e-07	0.55	0.46	0.14	FALSE
55	The Cancer Genome Atlas	Thyroid Carcinoma	TMEM165	0.12	0.08	enet	12	0.08	2.1e-08	6.6	-6.0	2.7e-09	-0.62	0.11	0.89	FALSE