Best TWAS P=1.08e-09 · Best GWAS P=4.53e-08 conditioned to 0.0168
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Breast Mammary Tissue (Female) | DCUN1D4 | 0.02 | 0.03 | lasso | 1 | 0.02 | 0.08240 | 5.2 | 5.2 | 1.7e-07 | 0.62 | 0.02 | 0.18 | FALSE |
| 2 | GTEx | Ovary | FRYL | 0.12 | -0.01 | enet | 21 | 0.03 | 0.07250 | 4.9 | 5.2 | 2.0e-07 | 0.58 | 0.06 | 0.53 | FALSE |
| 3 | GTEx | Thyroid | DCUN1D4 | 0.03 | 0.05 | lasso | 1 | 0.04 | 0.00024 | 5.2 | 5.2 | 1.7e-07 | 0.62 | 0.04 | 0.91 | FALSE |
| 4 | ROSMAP | Brain Pre-frontal Cortex | SGCB | 0.03 | 0.03 | enet | 9 | 0.03 | 0.00007 | 4.8 | 6.1 | 1.1e-09 | 0.58 | 0.06 | 0.93 | TRUE |
| 5 | The Cancer Genome Atlas | Prostate Adenocarcinoma | FRYL | 0.03 | 0.03 | enet | 8 | 0.03 | 0.00032 | 4.9 | 5.4 | 7.0e-08 | 0.46 | 0.03 | 0.86 | FALSE |