Best TWAS P=6.16e-08 · Best GWAS P=1.28e-07 conditioned to 0.00268
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | FBN2 | 0.18 | 0.20 | lasso | 6 | 0.24 | 3.7e-27 | -5.1 | -5.3 | 1.3e-07 | 0.51 | 0.00 | 1.00 | FALSE |
2 | The Cancer Genome Atlas | Lung Adenocarcinoma | FBN2 | 0.11 | 0.12 | blup | 159 | 0.14 | 2.2e-16 | -4.4 | -5.4 | 6.2e-08 | 0.49 | 0.03 | 0.96 | TRUE |