TWAS hub - FBN2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.2180	0.0390	0.0e+00	0.240	0.238	0.272	0.267	0.282	6.2e-29	1.1e-28	3.7e-33	1.9e-32	1.6e-34
2	METSIM	Adipose	0.1145	0.0260	0.0e+00	0.178	0.154	0.169	0.176	0.174	7.3e-26	2.5e-22	1.6e-24	1.3e-25	2.8e-25
3	NTR	Blood	0.0313	0.0110	1.3e-05	0.021	0.006	0.011	0.011	0.012	2.3e-07	4.8e-03	1.6e-04	1.2e-04	5.3e-05
4	ROSMAP	Brain Pre-frontal Cortex	0.0796	0.0249	5.8e-06	0.080	0.047	0.088	0.082	0.083	1.9e-10	9.3e-07	2.3e-11	1.1e-10	8.1e-11
5	TCGA	Breast Invasive Carcinoma	0.0241	0.0105	2.8e-04	0.026	0.015	0.021	NA	0.024	3.2e-06	3.4e-04	3.1e-05	NA	1.0e-05
6	TCGA	Colon Adenocarcinoma	0.0750	0.0330	4.0e-04	0.101	0.074	0.092	NA	0.083	1.8e-06	4.4e-05	5.4e-06	NA	1.6e-05
7	TCGA	Kidney Renal Clear Cell Carcinoma	0.1786	0.0436	0.0e+00	0.205	0.220	0.240	NA	0.244	1.1e-22	2.6e-24	1.0e-26	NA	3.7e-27
8	TCGA	Brain Lower Grade Glioma	0.1188	0.0407	1.4e-05	0.017	0.045	0.051	NA	0.042	4.8e-03	7.5e-06	1.7e-06	NA	1.4e-05
9	TCGA	Liver Hepatocellular Carcinoma	0.2370	0.0630	1.2e-10	0.240	0.238	0.244	NA	0.279	1.3e-11	1.5e-11	8.5e-12	NA	1.5e-13
10	TCGA	Lung Adenocarcinoma	0.1111	0.0310	2.0e-15	0.117	0.143	0.142	NA	0.142	1.5e-13	2.2e-16	2.7e-16	NA	3.0e-16
11	TCGA	Lung Squamous Cell Carcinoma	0.0277	0.0147	6.7e-03	0.018	0.014	0.014	NA	0.017	3.3e-03	9.8e-03	9.4e-03	NA	4.5e-03
12	TCGA	Pancreatic Adenocarcinoma	0.2110	0.0750	2.7e-05	0.066	0.104	0.093	NA	0.089	1.0e-03	4.2e-05	9.9e-05	NA	1.5e-04
13	TCGA	Pheochromocytoma and Paraganglioma	0.1870	0.0760	5.1e-05	0.197	0.093	0.154	NA	0.166	2.6e-08	1.5e-04	1.1e-06	NA	3.7e-07
14	TCGA	Prostate Adenocarcinoma	0.0380	0.0198	7.5e-03	0.017	0.010	0.005	NA	0.012	5.7e-03	2.6e-02	8.1e-02	NA	1.7e-02
15	TCGA	Skin Cutaneous Melanoma	0.1970	0.0920	3.0e-03	0.115	0.035	0.034	NA	0.105	5.4e-04	4.1e-02	4.2e-02	NA	9.4e-04
16	TCGA	Stomach Adenocarcinoma	0.0900	0.0370	2.1e-04	0.044	0.059	0.037	NA	0.043	4.0e-04	4.6e-05	1.0e-03	NA	4.4e-04
17	TCGA	Thyroid Carcinoma	0.1160	0.0390	4.8e-08	0.103	0.083	0.118	NA	0.112	3.2e-10	1.7e-08	1.5e-11	NA	5.0e-11

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17
Ever had prostate specific antigen (PSA) test	9.2	10.6	16.1	3.7	3.7	3.8	3.4	3.4	3.5	3.5	0.3	3.7	3.9	3.5	4.0	3.8	0.8	1.4	2.7	3.2
Impedance of arm (right)	7.0	32.8	51.2	-6.2	-6.4	-6.1	-6.1	-5.8	-4.5	-6.6	-2.8	-5.6	-7.2	-5.9	-5.8	-6.1	-5.3	-5.3	-5.4	-4.9
Medication: Blood pressure	6.6	11.7	22.6	2.3	3.5	3.2	3.2	3.2	4.8	4.1	2.8	4.1	4.3	3.5	4.0	3.4	0.6	2.3	3.8	2.8
Impedance of arm (left)	6.5	30.0	44.8	-6.1	-6.1	-5.9	-5.8	-5.6	-4.2	-6.2	-2.7	-5.3	-6.7	-5.6	-5.5	-5.9	-4.8	-5.4	-5.3	-4.8
Birth weight of first child	6.5	11.8	20.2	-3.2	-3.5	-3.6	-3.2	-3.5	-3.0	-3.8	-4.5	-3.5	-3.2	-3.5	-3.3	-3.5	-2.9	-2.8	-3.9	-3.2
Forced vital capacity (FVC), Best measure	5.9	21.6	32.5	-4.8	-4.7	-4.7	-4.4	-4.9	-4.9	-4.7	-4.1	-4.4	-5.7	-5.3	-4.7	-4.5	-2.4	-4.8	-5.3	-3.9
Forced expiratory volume in 1-second (FEV1), predicted percentage	5.9	12.6	17.1	-3.8	-3.5	-3.5	-3.6	-3.8	-3.4	-3.5	-3.6	-3.2	-3.9	-3.9	-3.2	-3.3	-3.1	-3.1	-4.1	-3.5
Illnesses of father: High blood pressure	5.1	6.3	10.3	1.1	2.6	2.5	2.1	2.4	2.9	3.0	0.9	3.2	2.9	2.5	2.5	2.6	1.3	2.7	2.8	2.9
Arm fat percentage (right)	4.9	19.3	27.9	-4.3	-4.8	-4.8	-4.8	-4.3	-4.6	-5.3	-3.0	-5.0	-5.2	-4.5	-4.4	-4.9	-2.5	-3.3	-4.2	-3.8
Arm fat percentage (left)	4.9	19.7	27.8	-4.4	-4.8	-4.9	-4.8	-4.3	-4.6	-5.3	-2.9	-5.0	-5.2	-4.6	-4.5	-4.9	-2.5	-3.5	-4.3	-3.8
Trunk fat percentage	4.8	19.1	29.3	-4.4	-5.0	-5.0	-4.9	-4.2	-4.5	-5.3	-1.4	-4.9	-5.4	-4.5	-4.7	-5.1	-2.0	-3.2	-3.5	-3.8
Forced expiratory volume in 1-second (FEV1), Best measure	4.7	15.0	24.8	-4.2	-3.9	-3.8	-3.6	-3.9	-4.2	-3.8	-2.8	-3.5	-5.0	-4.3	-4.1	-3.7	-2.6	-4.2	-4.4	-3.1
Hypertension (Self-reported)	4.7	13.1	23.0	2.0	3.7	3.2	3.0	3.2	4.8	4.4	3.0	4.1	4.8	3.5	3.5	3.4	3.9	2.7	4.0	3.1
Medication for hormone replacement therapy	4.6	5.1	12.3	-2.0	-2.4	-2.4	-2.4	-2.3	-2.3	-2.4	-3.5	-2.3	-1.9	-2.7	-2.6	-2.3	0.9	-1.5	-1.8	-1.7
Forced vital capacity (FVC)	4.6	17.8	26.6	-4.0	-4.4	-4.4	-4.1	-4.5	-4.1	-4.5	-4.0	-4.1	-5.2	-4.8	-4.0	-4.2	-2.4	-4.5	-4.6	-3.3
Medication for cholesterol, blood pressure or diabetes	4.5	7.5	16.6	-1.5	-2.8	-2.5	-2.5	-2.6	-4.1	-3.2	-2.5	-3.4	-3.2	-2.8	-3.0	-2.7	0.4	-2.0	-3.2	-2.2
Average weekly beer plus cider intake	4.4	6.4	8.1	-2.8	-2.8	-2.7	-2.3	-2.6	-2.2	-2.8	-2.2	-2.8	-2.7	-2.6	-2.6	-2.8	-1.5	-1.8	-2.6	-2.6
Lung FVC	4.3	21.7	43.1	-4.8	-4.8	-4.9	-4.4	-5.2	-3.0	-4.7	-6.6	-4.4	-4.3	-5.1	-2.9	-4.6	-3.3	-4.8	-5.5	-4.5
Trunk fat mass	4.0	17.2	25.6	-3.9	-4.8	-4.7	-4.6	-4.0	-4.5	-5.1	-2.1	-4.8	-5.0	-4.4	-4.4	-4.8	-0.9	-3.1	-3.4	-3.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	3.8	4.4	6.6	-1.5	-2.0	-2.2	-2.0	-2.2	-2.6	-2.4	-1.9	-2.2	-2.2	-2.5	-2.2	-2.0	-1.3	-0.7	-2.5	-2.4
High blood pressure (mother)	3.7	5.1	13.3	1.1	1.9	1.8	1.5	1.8	3.6	2.4	1.8	2.4	2.8	2.0	2.2	1.8	2.2	2.9	2.9	2.1
Chronotype (morning person)	3.6	8.2	13.8	-2.4	-3.3	-3.3	-3.7	-3.3	-1.7	-3.4	-3.6	-3.3	-2.2	-3.1	-2.2	-3.2	-0.4	-2.1	-2.6	-3.1
Body fat percentage	3.6	14.2	23.7	-3.6	-4.3	-4.2	-4.2	-3.6	-4.0	-4.5	-0.0	-4.3	-4.9	-3.9	-4.3	-4.4	-1.8	-2.7	-2.8	-3.5
Number of children fathered	3.6	4.1	5.7	-2.2	-2.4	-2.3	-2.2	-2.4	-0.9	-2.0	-1.6	-2.0	-2.0	-2.3	-2.0	-2.2	-0.8	-1.9	-2.0	-2.4
Medication: Gliclazide	3.6	4.1	7.5	-2.5	-2.3	-2.2	-2.6	-2.1	-1.9	-2.1	-1.8	-2.1	-1.6	-2.0	-1.9	-2.3	-0.4	-0.1	-1.8	-2.7
Exposure to tobacco smoke outside home	3.5	4.6	5.9	-2.4	-2.3	-2.3	-2.4	-2.1	-2.4	-2.1	-1.2	-2.4	-1.8	-2.1	-2.3	-2.4	2.0	-1.8	-2.3	-2.1
Medication: Lisinopril	3.5	4.6	8.8	1.5	2.4	2.2	2.2	1.9	1.9	3.0	2.7	2.7	1.7	1.8	2.0	2.5	0.8	1.7	2.5	1.8
Eye problems/disorders: None of the above	3.3	3.8	6.2	2.3	2.1	2.2	2.3	2.1	1.7	2.0	0.1	1.8	2.1	2.1	2.3	2.2	1.3	1.2	1.6	2.5
Exposure to tobacco smoke at home	3.2	3.6	5.5	-1.6	-2.0	-2.0	-2.3	-2.2	-1.7	-2.2	-2.0	-2.0	-1.8	-2.1	-1.7	-2.0	-0.7	-0.9	-1.9	-2.3
Fractured/broken bones in last 5 years	3.2	4.1	6.3	2.4	2.3	2.4	2.2	2.1	1.8	2.5	2.4	2.5	1.4	2.0	1.5	2.5	-0.8	0.7	1.8	2.1
Cardiovascular Disease	3.1	10.2	16.6	1.8	3.2	2.8	2.5	2.8	4.1	3.8	3.7	3.8	4.0	2.9	2.6	3.1	3.1	3.0	3.7	2.6
High blood pressure	3.1	8.7	16.2	1.3	2.9	2.5	2.4	2.5	4.0	3.6	2.4	3.4	4.0	2.8	2.8	2.7	3.9	2.0	3.1	2.4
Forced expiratory volume in 1-second (FEV1)	3.1	10.6	17.1	-3.2	-3.4	-3.2	-3.1	-3.3	-3.4	-3.3	-2.7	-3.0	-4.1	-3.6	-3.2	-3.1	-2.4	-3.4	-3.7	-2.5
Whole body fat mass	3.1	13.1	19.6	-3.3	-4.1	-4.1	-4.0	-3.5	-4.0	-4.4	-1.6	-4.2	-4.4	-3.9	-3.9	-4.2	-0.6	-2.8	-3.0	-3.1
Vascular/heart problems diagnosed by doctor	3.1	8.4	16.6	-1.4	-2.8	-2.4	-2.3	-2.5	-4.1	-3.5	-2.7	-3.3	-3.8	-2.7	-2.7	-2.6	-3.4	-1.9	-3.2	-2.4
Arm fat mass (right)	3.0	12.2	18.5	-3.0	-3.8	-3.9	-3.9	-3.4	-3.9	-4.3	-2.7	-4.1	-4.1	-3.7	-3.6	-4.0	-0.9	-2.8	-3.2	-2.7
Illnesses of father: None of the above (group 1)	2.9	3.6	9.0	-1.0	-1.7	-1.7	-1.8	-1.5	-2.2	-2.0	-1.8	-2.1	-1.9	-1.7	-1.9	-1.7	-0.3	-3.0	-2.9	-1.5
Arm fat mass (left)	2.9	11.7	17.1	-3.2	-3.8	-3.9	-3.8	-3.4	-3.7	-4.1	-2.6	-4.0	-3.9	-3.7	-3.5	-3.9	-0.5	-2.7	-3.2	-2.7
Mean Putamen Volume	2.6	3.0	7.7	-1.6	-1.5	-1.6	-1.5	-1.6	-1.7	-1.7	-2.3	-1.6	-1.6	-1.7	-1.8	-1.5	-0.5	-2.0	-2.8	-1.5
Eye problems/disorders: Cataract	2.6	3.0	5.8	-1.8	-1.8	-1.8	-1.9	-1.7	-1.9	-1.8	0.1	-1.7	-1.8	-2.0	-2.4	-1.9	0.3	-1.1	-1.6	-2.1
Alcohol usually taken with meals	2.5	4.0	5.7	2.2	2.1	2.2	2.3	2.0	1.5	2.0	2.4	1.9	2.1	2.1	1.8	2.0	1.5	1.8	2.1	1.8
Medication: Seretide 50 evohaler	2.5	2.9	5.0	-1.6	-1.9	-1.8	-2.2	-1.7	-1.8	-1.7	-1.2	-1.6	-2.2	-1.8	-1.8	-1.8	-0.5	-1.5	-1.5	-1.2
Number of operations (self-reported)	2.5	3.8	11.2	-1.2	-1.5	-1.5	-1.6	-1.4	-2.2	-2.1	-3.3	-1.9	-2.0	-1.5	-1.7	-1.6	-1.4	-2.7	-2.7	-1.1
Hayfever/allergic rhinitis (self-reported)	2.4	3.2	5.8	-2.4	-1.7	-1.8	-1.7	-1.7	-1.8	-1.8	-1.5	-1.7	-1.5	-1.9	-2.3	-1.8	0.5	-0.6	-2.4	-2.1
Pulse wave peak to peak time	2.4	2.9	6.3	-2.5	-1.7	-1.7	-1.7	-1.7	-1.1	-1.6	-1.4	-1.5	-1.6	-1.5	-1.9	-1.8	-0.2	-2.4	-2.0	-1.4
Tinnitus: Yes, now most or all of the time	2.4	2.9	5.3	1.1	1.7	1.6	1.3	1.7	2.3	1.9	1.4	1.7	1.9	1.7	1.6	1.6	0.4	2.1	1.9	1.8
Supplements: Calcium	2.4	2.6	5.4	1.5	2.1	2.1	1.8	1.7	1.1	2.3	1.5	2.1	1.3	1.6	1.6	2.1	0.1	1.0	0.9	1.1
Hair/balding pattern: Pattern 3	2.3	3.5	13.1	-1.7	-1.7	-1.9	-2.5	-1.9	-0.8	-1.6	-3.6	-1.7	-1.3	-1.9	-0.7	-1.8	0.4	-2.2	-1.9	-1.7
Basal cell carcinoma (self-reported)	2.3	2.7	5.2	2.2	1.7	1.7	1.5	1.9	0.9	1.7	0.9	1.6	1.4	1.8	1.5	1.7	0.5	1.8	1.9	2.3
Had major operations	2.2	2.5	5.6	-1.4	-1.4	-1.5	-1.8	-1.4	-2.1	-1.7	-2.4	-1.8	-1.5	-1.3	-1.4	-1.6	0.6	-1.2	-2.0	-1.1
Height	2.1	40.0	64.0	-5.5	-7.5	-7.1	-7.2	-6.6	-6.3	-7.6	-5.2	-6.8	-8.0	-7.4	-6.8	-7.2	0.2	-5.5	-4.4	-3.1
Allergy or Eczema	2.1	5.4	9.9	-2.5	-2.4	-2.4	-2.3	-2.1	-3.1	-2.4	0.1	-2.4	-3.1	-2.5	-2.8	-2.4	-1.1	-1.4	-2.2	-2.2
Health satisfaction	2.1	2.8	5.6	1.7	1.8	1.8	1.9	1.9	1.1	2.0	2.4	1.9	1.0	1.7	1.1	1.9	-0.8	0.6	1.8	2.0
Alcohol intake frequency.	2.1	4.8	7.1	1.8	2.4	2.3	2.4	2.4	2.5	2.4	1.2	2.6	2.7	2.3	2.1	2.5	-0.5	2.4	2.0	1.5
Average weekly red wine intake	2.1	3.1	4.1	1.6	1.9	2.0	1.9	2.0	0.9	2.0	1.9	1.8	1.8	1.9	1.4	1.8	1.5	1.5	1.8	1.9
Ulcerative Colitis (UC)	2.0	3.7	6.5	-2.4	-2.5	-2.4	-2.1	-2.2	-0.5	-2.3	-1.6	-2.1	-1.6	-2.1	-1.5	-2.5	-1.3	-0.5	-1.5	-2.2
Systolic Blood Pressure	2.0	10.2	30.2	0.2	2.5	2.1	1.7	1.9	5.5	3.9	3.8	3.5	4.1	2.2	2.7	2.4	4.6	2.3	4.0	2.6
Commuting to job workplace: Car/motor vehicle	2.0	2.3	3.6	1.2	1.4	1.5	1.6	1.5	1.7	1.6	1.3	1.7	1.5	1.5	1.4	1.4	0.9	1.8	1.3	1.9
Qualifications: nursing, teaching	2.0	3.2	5.4	2.1	2.0	1.9	2.1	1.7	2.3	1.8	1.8	2.0	1.5	1.8	1.4	2.0	-0.6	0.2	1.7	2.1
Medication: Bendroflumethiazide	2.0	3.0	12.3	0.1	1.4	1.1	1.1	0.9	3.5	2.1	-0.4	2.3	2.7	1.2	2.1	1.4	1.0	2.0	1.3	1.2
Alzheimer’s Disease (in mother)	1.9	2.2	4.1	2.0	1.5	1.5	1.5	1.7	0.1	1.5	1.7	1.3	1.3	1.7	0.9	1.4	1.1	1.5	1.7	1.6
Type 2 Diabetes (T2D) (2012)	1.9	2.2	6.8	1.8	1.5	1.5	1.3	1.2	1.6	1.6	2.6	1.3	1.1	1.4	1.4	1.5	0.6	0.3	2.0	1.1
Heel T-Score	1.8	14.0	30.4	-0.7	-3.1	-2.9	-2.9	-3.1	-5.5	-4.3	3.6	-4.6	-4.9	-3.1	-5.1	-3.3	2.4	-4.1	-2.5	-4.4
Medication: Metformin	1.8	2.5	4.1	-1.7	-2.0	-1.9	-1.8	-1.7	-1.4	-1.7	0.2	-1.8	-1.8	-1.6	-1.8	-1.9	-0.2	-1.0	-0.9	-1.8
Diabetes (father)	1.8	2.3	3.6	-1.7	-1.7	-1.9	-1.5	-1.8	-0.4	-1.8	0.1	-1.7	-1.6	-1.8	-1.8	-1.8	-0.1	-1.5	-0.9	-1.4
Leg fat-free mass (left)	1.8	9.7	49.7	-2.2	-2.8	-2.9	-2.6	-2.6	-3.3	-3.4	-7.0	-3.3	-2.2	-3.0	-2.0	-3.0	1.3	-2.2	-3.5	-1.1
Leg predicted mass (left)	1.8	9.7	50.4	-2.2	-2.8	-2.9	-2.6	-2.6	-3.3	-3.4	-7.1	-3.3	-2.1	-3.0	-2.0	-3.0	1.4	-2.2	-3.5	-1.1
Impedance of whole body	1.8	9.2	19.4	-3.1	-3.3	-2.9	-2.9	-2.7	-2.0	-2.9	3.8	-2.4	-4.4	-2.8	-3.7	-3.0	-3.3	-2.7	-1.4	-3.0
Impedance of leg (left)	1.7	8.3	116.6	0.8	0.3	0.8	0.8	1.0	0.9	1.2	10.8	1.4	-1.2	0.8	-1.3	0.7	-1.0	0.7	3.4	-0.2
Financial difficulties in last 2 years	1.7	2.2	5.4	1.6	1.8	1.8	2.3	1.9	0.6	1.6	1.3	1.8	1.0	1.8	1.1	1.9	-0.8	0.4	0.4	1.4
Headache pain in last month	1.7	2.9	4.5	1.0	1.9	1.7	1.6	2.1	1.2	2.0	1.9	1.7	1.9	2.1	1.5	1.6	0.5	2.1	1.6	1.7
Breast cancer (self-reported)	1.7	2.0	4.1	-1.6	-1.7	-1.7	-1.7	-1.6	-0.8	-1.5	-0.4	-1.2	-2.0	-1.7	-1.4	-1.5	-1.3	-1.3	-0.8	-0.5
Osteoporosis (self-reported)	1.7	2.1	3.7	1.3	1.7	1.7	1.2	1.7	1.4	1.7	1.2	1.9	0.9	1.5	1.2	1.8	-0.7	-0.0	1.5	1.9
Diastolic blood pressure, automated reading	1.7	5.4	11.1	1.0	2.3	2.0	1.6	2.0	3.3	2.8	2.2	2.6	2.7	2.1	2.3	2.1	1.2	2.5	3.0	2.5
Alzheimer’s Disease (including proxy)	1.6	2.3	3.4	1.6	1.5	1.4	1.5	1.7	0.7	1.7	1.8	1.4	1.3	1.7	1.2	1.4	1.0	1.5	1.7	1.8
Severe depression (siblings)	1.6	1.8	8.1	1.0	1.2	1.3	1.7	1.3	0.6	1.3	0.9	1.4	1.6	1.3	0.9	1.3	0.4	2.8	1.1	0.8
Stomach or abdominal pain in last month	1.6	2.0	3.2	1.2	1.5	1.3	1.3	1.5	1.4	1.3	0.9	1.4	1.1	1.4	1.8	1.4	-1.7	1.1	1.7	1.7
Heart attack	1.6	2.0	5.1	0.9	1.5	1.4	1.6	1.2	1.2	2.0	2.3	1.7	1.6	1.2	0.9	1.4	1.0	1.3	1.3	1.1
Pulse wave Arterial Stiffness index	1.6	1.8	5.0	2.2	1.3	1.4	1.3	1.4	0.5	1.2	1.2	1.2	1.1	1.1	1.5	1.4	0.4	1.9	1.6	1.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.6	1.9	6.4	1.0	1.2	1.2	1.3	1.0	1.1	1.4	1.5	1.3	1.3	1.2	1.3	1.1	1.3	2.5	1.9	1.2
Leg fat-free mass (right)	1.6	8.3	53.0	-1.9	-2.4	-2.6	-2.3	-2.3	-3.0	-3.0	-7.3	-2.9	-1.7	-2.7	-1.6	-2.6	1.4	-1.9	-3.2	-0.8
Mouth/teeth dental problems: Mouth ulcers	1.6	2.6	4.8	1.8	2.0	1.9	2.2	2.0	-0.3	1.5	1.8	1.6	1.1	1.9	1.1	1.8	-1.0	1.8	1.0	1.2
Leg predicted mass (right)	1.6	8.6	53.0	-1.9	-2.4	-2.6	-2.4	-2.4	-3.1	-3.0	-7.3	-3.0	-1.8	-2.8	-1.6	-2.6	1.4	-1.9	-3.3	-0.8
Heart attack/myocardial infarction (self-reported)	1.6	2.1	5.4	0.9	1.5	1.4	1.6	1.3	1.2	2.0	2.3	1.7	1.7	1.2	0.9	1.4	0.8	1.4	1.4	1.2
Impedance of leg (right)	1.5	7.2	104.0	0.6	-0.0	0.5	0.6	0.6	0.8	0.8	10.2	1.1	-1.4	0.5	-1.4	0.4	-0.9	0.3	3.1	-0.4
Ever had stillbirth, spontaneous miscarriage or termination	1.5	1.6	3.1	0.6	1.6	1.5	0.8	1.5	1.1	1.5	0.5	1.7	1.0	1.5	1.8	1.4	-1.0	0.7	0.9	1.4
Major Depression (MDD)	1.4	1.7	2.8	-0.9	-1.2	-1.3	-1.5	-1.5	-1.6	-0.8	-1.5	-1.1	-0.8	-1.7	-1.5	-0.9	1.4	-0.9	-1.6	-1.5
Time employed in main current job	1.4	1.6	2.7	-1.3	-1.4	-1.5	-1.3	-1.6	-1.2	-1.4	-1.0	-1.4	-0.9	-1.5	-1.2	-1.4	0.5	0.1	-1.1	-1.6
Qualifications: A levels/AS levels or equivalent	1.4	3.0	5.1	2.1	1.9	2.0	2.1	1.8	1.5	1.7	1.4	1.8	1.4	1.8	1.5	2.0	-0.2	0.7	1.9	2.3
Qualifications: O levels/GCSEs or equivalent	1.4	2.2	4.5	1.4	1.6	1.8	2.0	1.8	1.3	1.5	-0.4	1.6	1.6	1.8	1.6	1.6	0.2	0.4	0.9	2.1
Emphysema/chronic bronchitis	1.4	1.6	8.7	-0.3	-1.0	-0.9	-0.9	-0.9	-1.1	-1.2	-3.0	-1.4	-1.3	-0.8	0.0	-1.0	-1.6	-1.7	-1.0	-0.7
Angina (self-reported)	1.4	1.8	6.3	0.9	1.0	0.8	0.9	1.0	1.2	1.1	2.5	1.1	0.9	0.8	0.9	0.9	1.0	2.1	2.2	1.5
Fasting Glucose	1.3	1.6	3.2	-0.8	-1.1	-1.1	-1.0	-1.2	-1.6	-1.2	-1.0	-1.2	-1.3	-1.3	-1.1	-0.8	-1.3	-1.7	-1.5	-1.8
Diabetes (mother)	1.3	1.6	2.8	-1.4	-1.2	-1.3	-1.6	-1.3	-1.4	-1.5	-0.7	-1.2	-1.4	-1.3	-1.7	-1.3	0.2	-0.6	-1.4	-1.4
Qualifications: None of the above	1.3	2.9	5.0	-1.5	-2.1	-2.2	-2.2	-1.8	-1.1	-1.9	-0.8	-2.0	-1.5	-1.8	-1.7	-2.1	0.2	-0.4	-1.3	-2.1
Weight	1.3	6.2	10.5	-1.8	-2.7	-2.8	-2.6	-2.3	-3.2	-3.1	-2.3	-3.0	-2.9	-2.7	-2.7	-2.8	0.8	-1.9	-2.1	-1.4
Standing height	1.3	12.7	18.6	-2.7	-4.2	-3.9	-3.7	-3.8	-3.6	-4.2	-3.2	-3.8	-4.2	-4.3	-3.9	-4.0	1.5	-3.7	-2.6	-1.7
Qualifications: College or University degree	1.3	4.0	9.5	2.2	2.1	2.2	2.3	1.7	2.4	2.0	3.1	2.1	1.8	1.8	1.7	2.1	0.4	0.7	2.1	1.7
Average weekly champagne plus white wine intake	1.3	1.9	3.4	1.4	1.6	1.7	1.7	1.5	0.3	1.6	1.5	1.7	0.3	1.3	1.0	1.7	0.2	-0.6	1.2	1.9
Medication: Blood pressure	1.3	2.4	10.1	-0.3	1.1	0.8	0.5	0.7	3.0	1.8	0.1	1.7	2.2	0.9	1.4	1.0	3.2	0.4	1.7	1.2
Age started oral contraceptive pill	1.3	1.6	4.3	-0.8	-1.4	-1.4	-1.5	-1.5	-0.5	-1.5	-0.7	-1.5	-0.8	-1.4	-1.2	-1.4	2.1	-0.6	-0.7	-1.1
Hand grip strength (right)	1.2	3.3	5.7	-1.2	-2.0	-1.9	-1.7	-2.2	-2.4	-1.9	-0.8	-2.2	-2.3	-2.2	-1.7	-2.0	-0.2	-1.2	-1.6	-2.0
Leg fat mass (right)	1.2	4.7	8.4	-1.5	-2.5	-2.4	-2.3	-1.9	-2.9	-2.7	0.7	-2.7	-2.9	-2.2	-2.7	-2.5	0.4	-1.3	-1.1	-1.8
Guilty feelings	1.2	1.8	3.2	-1.6	-1.6	-1.8	-1.2	-1.6	0.0	-1.5	-1.3	-1.4	-1.0	-1.4	-1.1	-1.6	-1.4	-0.3	-1.2	-1.2
Wears glasses or contact lenses	1.2	1.4	7.1	0.3	0.5	0.3	-0.0	0.3	2.0	0.8	-0.8	0.8	1.8	0.6	1.5	0.4	2.7	1.2	1.4	0.4
Angina	1.1	1.5	5.6	0.9	0.8	0.7	0.9	0.9	0.9	1.0	2.4	0.9	0.8	0.7	0.7	0.8	0.9	2.1	2.0	1.4
Had menopause	1.1	1.4	2.6	-1.1	-1.6	-1.5	-1.5	-1.5	-0.2	-1.5	-1.5	-1.4	-0.5	-1.3	-0.9	-1.5	1.0	-0.0	-0.4	-1.0
Had other major operations	1.1	1.3	2.8	-0.8	-1.2	-1.3	-1.0	-1.2	-0.8	-1.3	-1.7	-1.0	-1.0	-1.4	-1.2	-1.1	-1.0	-1.2	-1.1	-0.6
Mean time to correctly identify matches	1.1	2.1	4.3	-1.0	-1.5	-1.6	-1.4	-1.6	-1.3	-1.6	-0.9	-1.5	-2.1	-1.5	-1.3	-1.5	-1.6	-1.8	-1.2	-1.1
Age at First Birth	1.0	1.5	4.3	1.2	1.2	1.1	0.9	1.6	0.1	1.3	1.4	1.2	1.3	0.9	1.0	1.2	0.8	2.1	1.3	0.8
Other serious medical condition/disability diagnosed by doctor	1.0	1.2	2.2	-0.9	-1.3	-1.3	-1.2	-1.0	-1.1	-1.3	-0.6	-1.2	-1.5	-1.1	-1.0	-1.3	-1.0	-0.7	-1.1	-1.0
Ever used hormone-replacement therapy (HRT)	1.0	1.3	5.2	-1.1	-1.1	-1.2	-1.7	-1.0	-0.5	-0.9	-2.3	-1.0	-0.3	-1.3	-0.6	-1.2	1.5	-0.4	-0.5	-0.6
Systolic blood pressure, automated reading	1.0	2.9	14.1	-0.5	0.9	0.6	0.3	0.5	3.8	1.7	1.5	1.5	2.1	0.8	1.3	0.8	2.8	1.5	2.4	1.4
Hayfever, allergic rhinitis or eczema	1.0	2.2	5.7	-1.7	-1.4	-1.4	-0.9	-1.2	-2.4	-1.3	1.3	-1.3	-2.0	-1.5	-2.0	-1.4	-1.0	0.7	-1.4	-1.6
Alcohol intake versus 10 years previously	1.0	1.5	2.6	0.9	1.3	1.2	0.7	1.4	1.6	1.4	0.6	1.4	1.6	1.3	1.2	1.3	-1.3	0.5	1.3	0.8
Medication: Amlodipine	1.0	1.4	9.2	-1.3	-0.1	-0.5	-0.7	-0.3	1.7	0.4	-0.9	0.3	2.0	-0.1	0.8	-0.4	3.0	1.5	0.6	-0.8
Family relationship satisfaction	1.0	1.2	5.3	1.3	0.9	1.0	1.6	0.9	1.0	0.8	2.3	0.9	0.8	1.1	0.5	0.9	0.2	1.2	1.3	0.4
Leg pain on walking	1.0	1.3	2.1	1.0	1.1	1.0	1.2	1.4	1.2	0.8	0.0	1.2	1.3	1.3	1.4	0.9	-0.6	1.4	1.0	1.3
Illnesses of father: Heart disease	1.0	1.4	3.4	0.6	1.1	1.1	1.3	0.9	1.6	1.2	0.7	1.5	1.2	0.9	1.3	1.3	-0.3	1.4	1.8	1.3
Long-standing illness, disability or infirmity	1.0	1.5	2.8	-1.3	-1.4	-1.4	-1.7	-1.1	-1.3	-1.4	-0.3	-1.3	-1.4	-1.1	-1.1	-1.5	-0.6	-0.5	-1.1	-1.5
Mother’s age at death	1.0	1.3	2.7	-0.8	-1.3	-1.3	-1.3	-1.3	-1.4	-1.3	-0.7	-1.2	-1.2	-1.2	-0.8	-1.3	-0.7	-0.2	-0.8	-1.6
Myopia	1.0	1.5	4.4	-0.7	-1.3	-1.2	-1.2	-1.2	-1.2	-1.5	-0.9	-1.5	-1.3	-1.0	-0.5	-1.3	-1.0	-0.8	-1.0	-2.1
Leg fat mass (left)	1.0	4.1	8.2	-1.4	-2.3	-2.2	-2.1	-1.7	-2.9	-2.5	0.7	-2.5	-2.7	-2.0	-2.5	-2.4	0.4	-1.1	-1.0	-1.7
Blood Platelet Count	0.9	10.5	14.4	-3.3	-3.4	-3.5	-3.4	-3.2	-3.3	-3.5	-2.3	-3.6	-3.8	-3.2	-2.8	-3.5	-1.6	-3.6	-3.4	-2.9
Blood Red Count	0.9	8.3	10.8	-2.8	-3.1	-3.1	-3.0	-3.1	-3.2	-3.0	-1.5	-3.3	-2.8	-3.3	-2.8	-3.2	2.5	-1.6	-2.9	-3.1
Eye problems/disorders: Diabetes related eye disease	0.9	1.0	2.3	-1.5	-1.0	-1.0	-0.8	-1.0	-0.2	-0.8	0.3	-0.8	-0.8	-0.8	-1.1	-1.0	-0.9	-1.4	-1.2	-1.5
Relative age voice broke	0.9	1.4	3.8	-0.8	-1.1	-1.0	-1.4	-1.0	-0.9	-1.2	-1.8	-1.3	-1.2	-0.8	-0.3	-1.1	-1.1	-1.9	-1.1	-1.1
Multivitamins +/- minerals	0.9	1.2	2.6	1.1	1.1	1.1	1.2	1.4	0.3	0.9	1.2	0.9	0.6	1.3	0.8	0.9	-0.3	1.3	1.5	1.6
Frequency of tenseness / restlessness in last 2 weeks	0.9	1.4	3.4	0.7	1.1	1.1	1.6	1.3	0.8	1.1	1.7	1.2	0.8	1.1	0.8	1.1	-1.8	0.7	0.8	1.1
Pulse rate	0.9	1.5	5.4	1.6	1.1	1.1	1.2	1.3	0.2	0.8	-0.3	0.8	1.2	1.3	1.6	1.0	-1.5	2.3	0.9	0.9
Mouth/teeth dental problems: Dentures	0.9	1.5	2.5	1.3	1.2	1.2	0.9	1.3	1.2	1.2	1.2	1.4	1.6	1.4	0.9	1.3	0.8	1.2	1.0	1.1
Medication: Lansoprazole	0.9	1.0	1.8	0.6	1.0	0.9	0.9	1.0	1.0	1.2	0.9	1.1	1.0	1.0	1.4	0.9	0.1	1.1	1.2	1.0
Illnesses of mother	0.9	1.1	3.6	-0.8	-0.6	-0.6	0.1	-0.7	-1.9	-1.0	-0.2	-1.0	-1.4	-0.9	-1.1	-0.7	-1.2	-1.3	-1.7	-1.0
Mouth/teeth dental problems: Bleeding gums	0.9	1.1	2.6	-1.3	-1.2	-1.1	-1.1	-1.1	-0.6	-1.1	-0.1	-1.2	-0.7	-0.8	-1.4	-1.2	-0.4	0.8	-1.1	-1.6
Worry too long after embarrassment	0.9	1.5	2.6	-1.4	-1.5	-1.4	-0.8	-1.2	-1.2	-1.2	-0.4	-1.4	-1.6	-1.3	-0.8	-1.4	-1.6	-0.6	-1.0	-1.0
Migraine (self-reported)	0.9	1.1	7.4	-0.1	0.6	0.6	0.3	0.7	1.0	1.0	1.2	1.0	0.8	0.7	0.8	0.6	-0.8	2.7	1.3	0.9
Illness, injury, bereavement, stress in last 2 years	0.9	1.1	2.2	-1.0	-0.8	-1.0	-1.3	-1.0	-0.9	-0.7	0.7	-1.0	-1.4	-1.2	-1.4	-0.9	1.2	-1.5	-0.7	-0.8
Heart disease (siblings)	0.9	1.1	2.8	1.1	1.0	0.9	0.5	0.7	1.4	1.3	0.6	1.3	1.4	0.8	0.8	1.1	0.9	1.7	1.3	0.5
Reaction Time	0.8	1.5	6.0	-0.5	-1.0	-0.9	-0.7	-0.8	-1.5	-1.2	-0.2	-1.1	-2.0	-0.9	-1.1	-0.9	-2.4	-1.9	-1.2	-0.3
Medication: Atenolol	0.8	1.0	5.0	-0.6	0.6	0.4	0.1	0.2	2.2	1.2	1.0	1.0	1.4	0.5	0.9	0.5	1.9	-0.0	1.1	0.2
Sitting height	0.8	5.4	16.5	-1.3	-2.4	-2.3	-2.8	-2.4	-3.1	-1.9	-0.4	-2.2	-2.4	-2.8	-2.9	-2.3	4.1	-1.2	-0.8	-1.4
Waist circumference	0.8	3.0	6.0	-1.1	-2.0	-2.0	-1.8	-1.5	-2.1	-2.5	-0.9	-2.3	-2.1	-1.7	-1.8	-2.1	-1.0	-1.0	-1.3	-1.2
Heel bone mineral density (BMD) T-score, automated (right)	0.8	1.9	4.2	-0.0	-1.4	-1.3	-1.1	-1.4	-1.7	-1.7	0.5	-1.9	-2.0	-1.3	-1.4	-1.4	0.3	-1.6	-0.5	-1.5
Worrier / anxious feelings	0.8	1.5	2.2	1.0	1.2	1.1	1.4	1.2	1.5	1.5	1.4	1.4	1.2	1.0	1.1	1.2	-0.0	0.8	1.5	1.4
Glaucoma (self-reported)	0.8	0.9	1.9	0.7	1.2	1.2	1.2	1.0	0.5	1.4	1.2	1.4	0.6	1.0	0.5	1.3	-1.2	-0.0	0.2	0.2
Gout (self-reported)	0.8	1.1	2.0	0.9	0.9	0.7	1.0	1.0	1.2	1.1	1.4	0.9	1.1	0.9	0.9	0.8	1.1	0.6	1.4	1.0
Birth weight	0.8	1.7	3.5	-1.3	-1.2	-1.3	-1.2	-1.4	-1.4	-1.0	-1.5	-1.1	-1.6	-1.3	-0.9	-1.3	-1.8	-0.3	-1.9	-1.3
Leg fat percentage (right)	0.8	2.9	21.5	-0.4	-1.3	-1.1	-1.2	-0.6	-1.9	-1.3	4.6	-1.3	-2.2	-0.9	-2.2	-1.3	-0.2	0.0	0.6	-1.5
Ever depressed for a whole week	0.8	1.0	2.8	-0.7	-0.6	-0.5	-0.3	-0.5	-1.4	-0.9	-1.4	-0.6	-1.2	-0.6	-0.9	-0.5	-1.5	-1.2	-1.7	-0.7
Prostate Cancer	0.7	1.0	3.6	0.5	1.1	1.0	1.2	0.9	0.3	1.1	1.2	1.1	1.0	0.6	0.1	1.0	1.9	1.1	0.9	0.9
Bipolar Disorder (2011)	0.7	0.7	2.0	1.4	1.0	1.1	0.9	0.9	-0.7	0.8	1.2	0.8	0.2	1.0	0.5	1.0	0.0	0.3	0.7	0.4
Hand grip strength (left)	0.7	1.9	3.4	-0.8	-1.7	-1.5	-1.4	-1.7	-1.6	-1.6	-0.2	-1.8	-1.7	-1.7	-1.2	-1.7	0.1	-0.7	-0.9	-1.4
Vitamin and mineral supplements	0.7	0.9	1.5	-0.9	-1.0	-1.1	-1.2	-1.2	-0.2	-0.9	-1.1	-0.8	-0.7	-1.2	-0.5	-0.9	-0.3	-1.2	-0.9	-1.1
Supplements: Zinc	0.7	0.8	1.8	0.9	1.2	1.3	1.0	1.1	-0.5	1.3	0.9	1.2	0.5	0.8	0.1	1.3	0.6	0.3	-0.2	0.1
Diverticular disease/diverticulitis (self-reported)	0.7	0.8	2.6	-0.9	-0.6	-0.7	-0.8	-0.6	-0.6	-1.1	-1.6	-0.9	-0.3	-0.6	-0.7	-0.8	-0.8	-0.2	-1.5	-1.3
Pain all over the body in last month	0.7	0.7	3.2	0.6	0.7	0.9	1.2	1.1	-0.4	0.6	1.2	0.8	0.1	1.0	0.1	0.8	-1.8	0.5	-0.0	0.7
Frequency of tiredness / lethargy in last 2 weeks	0.7	1.2	5.5	0.8	1.1	0.9	1.2	1.1	0.7	0.9	1.4	1.2	0.6	0.9	0.8	1.1	-2.3	0.5	0.7	1.0
Prospective memory result	0.7	0.9	4.5	1.0	0.2	0.3	0.4	0.4	-0.3	0.3	2.1	0.2	0.3	0.1	0.0	0.3	1.9	1.4	1.5	0.6
Loud music exposure frequency	0.7	0.8	6.1	0.5	0.8	0.7	1.0	0.6	0.2	0.6	2.5	0.8	0.0	0.6	-0.3	0.8	-1.1	-0.1	0.4	0.8
Shortness of breath walking on level ground	0.7	0.8	1.9	0.9	0.6	0.6	0.9	0.7	1.0	0.8	1.1	0.7	0.8	0.8	1.0	0.6	1.2	0.4	0.9	1.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.7	0.8	4.6	0.0	0.4	0.4	0.6	0.4	2.2	0.7	-0.4	0.7	1.2	0.7	1.6	0.4	-0.5	0.0	1.1	0.5
Illnesses of siblings: Diabetes	0.7	0.8	1.8	-1.0	-1.0	-1.0	-0.9	-1.1	-0.2	-1.1	-1.4	-0.8	-0.4	-0.8	-0.4	-1.1	0.6	-0.5	-1.0	-1.3
Commuting to job workplace: Walk	0.7	0.7	1.6	1.3	1.1	1.0	0.9	1.1	0.3	0.9	0.2	0.7	0.7	1.1	0.8	0.9	-0.5	-0.4	0.8	1.0
Hearing aid user	0.7	0.8	1.6	1.3	1.1	1.0	0.6	1.0	0.6	1.2	-0.1	1.2	0.6	0.8	1.0	1.1	0.1	-0.0	0.6	1.1
Leg fat percentage (left)	0.7	2.6	22.5	-0.3	-1.1	-0.9	-1.0	-0.4	-1.9	-1.1	4.7	-1.1	-2.0	-0.7	-2.1	-1.1	-0.2	0.3	0.6	-1.3
HbA1C	0.6	0.6	1.8	1.3	-0.1	0.1	-0.4	-0.0	-0.7	1.0	-0.4	0.8	-0.9	-1.1	-0.7	1.4	0.2	-1.1	-0.9	-0.4
Type 2 Diabetes (T2D) (2018)	0.6	1.2	4.5	-0.6	-1.0	-0.9	-0.6	-0.8	-1.6	-0.9	2.1	-0.9	-1.2	-0.8	-1.7	-1.0	0.0	0.5	-0.3	-1.4
Neuroticism	0.6	1.5	3.7	-1.9	-1.5	-1.6	-1.2	-1.2	-0.6	-1.3	0.1	-1.3	-1.2	-1.2	-1.2	-1.6	-1.0	0.3	-1.0	-1.5
Average weekly spirits intake	0.6	0.7	2.8	-0.6	-0.8	-0.9	-0.6	-0.6	-1.7	-0.8	-0.9	-0.9	-1.3	-0.8	-0.8	-0.9	-0.2	-0.3	-0.4	-0.3
Ever had hysterectomy (womb removed)	0.6	0.7	2.8	-1.0	-0.7	-0.9	-1.1	-0.9	0.6	-0.7	-1.1	-0.7	-0.2	-0.8	0.1	-0.8	0.2	-1.7	-0.7	-0.8
Hair/balding pattern: Pattern 2	0.6	0.8	2.1	0.4	0.7	0.8	1.3	0.9	0.7	0.9	1.4	1.0	0.9	0.7	0.1	0.9	-0.8	1.1	0.5	0.7
Hip circumference	0.6	2.5	4.1	-1.5	-1.8	-1.8	-1.8	-1.3	-1.9	-1.9	-2.0	-1.7	-1.6	-1.8	-1.3	-1.9	0.8	-1.3	-1.1	-0.5
Serious illness, injury or assault of a close relative in last 2 years	0.6	0.7	1.6	1.3	0.6	0.7	1.2	0.6	1.0	0.5	-0.1	0.5	1.2	0.9	1.1	0.7	-0.6	0.3	1.1	1.0
Medication: Cholesterol lowering	0.6	0.9	3.0	-0.0	0.8	0.6	0.4	0.7	1.7	1.1	1.5	1.2	1.0	0.9	0.9	0.6	-0.1	0.5	1.6	0.6
Pulse wave reflection index	0.6	0.8	3.2	1.3	1.1	1.0	0.6	0.9	0.2	1.0	1.8	0.9	0.6	0.8	0.3	1.1	0.4	0.5	0.7	0.2
Reason for reducing amount of alcohol drunk: Health precaution	0.6	0.7	3.9	-0.8	-0.8	-0.8	-1.3	-0.9	-0.4	-0.5	-0.3	-0.8	-0.5	-0.8	-0.5	-0.7	2.0	-0.5	0.4	-0.2
Diabetes diagnosed by doctor	0.6	1.0	2.5	-0.5	-0.9	-0.9	-0.8	-0.8	-1.6	-0.8	1.6	-0.9	-1.2	-0.8	-1.5	-0.9	0.3	-0.3	-0.6	-1.4
Back pain experienced in last month	0.6	0.9	1.7	1.1	1.0	1.0	0.9	0.9	1.1	1.0	0.0	1.0	1.0	1.1	1.3	1.1	-0.4	0.4	1.1	0.5
Financial situation satisfaction	0.6	0.7	1.6	0.7	1.1	1.0	1.3	1.2	-0.1	1.0	1.0	1.0	0.3	0.8	0.2	1.1	-0.2	0.2	0.4	1.2
Eye problems/disorders: Glaucoma	0.6	0.7	4.5	0.7	0.9	0.8	0.8	0.7	0.1	1.0	0.8	1.1	0.3	0.6	0.4	1.0	-2.1	0.6	0.3	0.1
High cholesterol (Self-reported)	0.6	1.0	4.0	0.9	0.7	0.7	0.5	0.7	1.1	0.6	1.3	1.0	0.9	0.8	0.7	0.7	-0.2	1.8	2.0	0.6
Unable to work because of sickness or disability	0.6	0.7	1.8	1.0	0.8	0.8	1.3	1.1	0.3	0.6	0.9	0.7	0.7	1.1	0.5	0.8	-0.9	1.2	0.3	0.7
Intelligence (Savage-Jansen 2018)	0.5	1.5	2.3	1.3	1.4	1.4	1.4	1.3	0.9	1.0	1.5	1.1	1.0	1.5	1.2	1.3	-0.4	1.2	1.1	0.9
Smoking Status	0.5	1.3	2.8	1.4	1.2	1.2	1.5	1.2	1.2	1.3	0.1	1.2	1.4	1.2	1.7	1.2	0.1	0.1	0.4	0.8
Bilateral oophorectomy (both ovaries removed)	0.5	0.6	3.0	-1.4	-0.6	-0.7	-0.8	-0.6	0.1	-0.7	-1.7	-0.5	0.1	-0.6	-0.1	-0.7	0.6	-0.4	-1.0	-0.5
Heel bone mineral density (BMD) T-score, automated (left)	0.5	1.2	2.4	0.3	-1.1	-1.0	-0.9	-1.1	-1.2	-1.4	1.1	-1.5	-1.6	-1.0	-1.1	-1.1	0.5	-1.2	0.2	-1.1
Tinnitus: Yes, but not now, but have in the past	0.5	0.5	1.5	-1.0	-0.5	-0.6	-0.3	-0.7	-0.5	-0.5	-0.3	-0.5	-0.8	-0.6	-0.6	-0.6	-1.1	-1.2	-0.9	-1.0
Qualifications: CSEs or equivalent	0.5	0.7	2.9	-0.8	-0.4	-0.4	-0.3	-0.3	-1.0	-0.5	-1.3	-0.4	-0.4	-0.4	-1.2	-0.3	-1.2	-0.8	-1.7	-0.9
Allergy	0.5	1.1	2.9	1.1	1.0	1.1	0.5	0.8	1.7	1.0	-0.4	0.9	1.5	1.1	1.4	1.0	0.5	-0.3	0.9	0.9
Depression (self-reported)	0.5	0.6	2.6	0.9	0.6	0.6	0.8	0.7	-0.0	0.3	0.6	0.6	0.5	0.6	0.2	0.6	-1.6	1.6	0.2	-0.2
Peak expiratory flow (PEF)	0.5	1.2	3.1	-1.4	-1.0	-0.9	-1.2	-1.0	-0.8	-0.7	-0.0	-0.7	-1.4	-1.2	-1.4	-0.8	-0.7	-1.8	-1.5	-0.7
Medication: Paracetamol	0.5	0.8	1.5	0.6	0.8	0.8	0.6	1.0	0.6	0.8	-0.7	0.8	1.1	1.0	1.2	0.6	0.7	1.1	0.9	1.2
Chronic bronchitis/emphysema (mother)	0.5	0.5	2.0	0.0	-0.7	-0.5	-0.6	-0.6	-0.8	-0.6	-0.7	-0.6	-0.7	-0.8	-1.0	-0.5	0.2	-1.4	-0.8	-0.7
Neck or shoulder pain in last month	0.5	0.6	2.9	-0.1	0.7	0.4	0.5	0.6	1.0	0.7	0.4	0.8	1.1	0.7	1.1	0.6	-1.7	0.9	0.5	-0.1
Commuting to job workplace: Public transport	0.5	0.6	1.8	0.9	0.8	0.8	0.9	0.9	-0.2	0.8	1.3	0.6	0.1	0.7	0.4	0.9	-0.6	-0.1	0.9	0.7
Basal metabolic rate	0.5	2.8	14.4	-0.5	-1.4	-1.4	-1.2	-1.2	-2.2	-1.8	-3.8	-1.8	-1.0	-1.6	-1.1	-1.5	2.3	-1.0	-1.4	0.0
Commuting to job workplace: Cycle	0.5	0.5	2.2	0.7	0.6	0.8	1.0	0.6	0.9	0.4	0.4	0.6	0.8	0.8	0.8	0.7	-1.5	0.4	0.4	0.3
Schizophrenia vs Biploar Disorder	0.4	0.5	3.9	0.0	0.2	0.2	0.1	0.3	-0.2	0.3	-0.7	0.2	0.1	0.2	0.4	0.2	2.0	-1.5	0.0	0.9
LDL Cholesterol	0.4	0.7	4.0	-0.0	-0.5	-0.4	-0.5	-0.7	-1.5	-0.7	-2.0	-0.8	-0.2	-0.6	-0.2	-0.6	0.9	-0.2	-1.0	-1.0
Waist Hip Ratio (WHR)	0.4	1.9	7.0	0.2	-1.2	-1.0	-0.6	-0.9	-1.0	-1.8	2.6	-1.5	-1.8	-0.9	-1.5	-1.1	-2.1	-0.8	-0.6	-1.7
Hypothyroidism (self reported)	0.4	0.8	5.5	1.2	0.8	0.7	0.4	0.7	-0.1	0.6	2.4	0.5	0.4	0.6	-0.2	0.7	1.8	-0.4	0.5	0.2
Respiratory disease	0.4	1.0	1.5	-1.1	-1.1	-1.2	-0.9	-0.8	-0.9	-1.2	-0.2	-1.1	-1.2	-0.9	-0.9	-1.2	-1.0	-1.1	-0.8	-0.8
Number of treatments/medications taken	0.4	0.7	3.2	-0.3	0.7	0.4	0.3	0.7	1.8	1.0	-0.1	1.2	1.3	0.8	1.0	0.5	-0.2	0.3	1.1	0.7
Frequency of depressed mood in last 2 weeks	0.4	0.6	2.7	-0.2	0.7	0.5	1.3	0.8	0.3	0.7	1.6	0.8	0.5	0.8	0.1	0.6	-1.0	0.4	-0.3	0.2
Maternal smoking around birth	0.4	0.5	1.5	-0.5	-0.5	-0.6	-0.5	-0.7	-0.6	-0.7	0.3	-0.6	-0.5	-0.5	-1.2	-0.6	-1.2	-0.5	-1.0	-1.0
Mouth/teeth dental problems	0.4	0.6	4.0	-0.5	-0.6	-0.7	-0.4	-0.7	-0.5	-0.6	-1.4	-0.7	-0.8	-0.7	-0.2	-0.6	0.5	-2.0	-0.4	0.1
Diabetes (self-reported)	0.4	0.7	4.1	-0.1	-0.4	-0.5	-0.3	-0.3	-1.3	-0.4	2.0	-0.5	-0.9	-0.3	-1.3	-0.5	0.4	-0.5	-0.3	-1.0
Medication: Ramipril	0.4	0.6	3.6	-1.1	0.3	0.0	-0.1	-0.1	1.9	0.7	0.8	0.6	1.1	0.2	0.3	0.1	1.3	0.2	0.6	0.0
Number of live births	0.4	0.5	1.8	-1.2	-0.4	-0.5	-0.5	-0.5	-0.6	-0.4	0.4	-0.4	-0.7	-0.5	-1.0	-0.6	1.3	-1.0	-0.8	-0.3
Happiness	0.4	0.5	6.5	-0.1	-0.3	-0.3	0.5	-0.2	-0.3	-0.3	2.5	-0.4	-0.9	-0.2	-0.5	-0.4	-0.4	0.1	0.0	-0.4
Ever highly irritable/argumentative for 2 days	0.4	0.4	1.1	-0.3	-0.7	-0.7	-0.4	-0.8	-0.7	-0.7	-0.3	-0.6	-0.7	-0.9	-1.0	-0.6	-0.1	-0.7	-0.6	-0.5
Medication: Ventolin 100micrograms inhaler	0.4	0.5	2.4	0.0	0.5	0.4	0.4	0.5	0.7	0.8	1.6	0.7	0.6	0.5	0.9	0.4	0.6	0.6	0.9	0.4
High blood pressure (siblings)	0.4	0.5	1.5	-1.2	-0.7	-0.9	-0.7	-1.0	0.8	-0.5	-0.1	-0.4	0.2	-0.6	-0.2	-0.8	1.1	0.3	-0.1	-1.2
Wheeze or whistling in the chest in last year	0.4	0.7	3.5	0.4	0.5	0.4	0.8	0.6	0.9	0.7	0.5	0.5	1.3	0.6	1.1	0.4	1.1	1.9	0.9	0.0
Medication: Ibuprofen	0.4	0.5	4.5	-0.1	0.2	0.2	0.2	0.2	-1.0	0.3	0.7	0.1	-0.6	-0.1	-0.4	0.2	0.5	-2.1	-1.0	0.1
Heart disease (mother)	0.4	0.5	2.6	0.3	0.4	0.4	0.2	0.2	1.6	0.7	-0.5	0.8	1.2	0.4	1.0	0.5	0.3	0.8	0.9	0.1
Pulse rate, automated reading	0.4	1.4	10.7	1.3	1.2	1.0	1.3	1.2	-0.5	0.7	-0.0	0.6	1.2	1.2	0.9	0.9	-0.0	3.3	0.8	0.5
Medication: Aspirin	0.4	0.6	2.0	0.4	0.6	0.4	0.7	0.6	1.1	0.7	1.0	0.7	0.7	0.6	0.4	0.5	-0.5	0.6	1.4	0.9
Knee pain experienced in last month	0.4	0.6	2.8	-0.0	0.3	0.2	0.4	0.3	1.7	0.4	-1.0	0.6	1.2	0.5	0.9	0.3	-0.6	0.7	0.5	0.9
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.8	2.8	-0.4	-0.5	-0.6	-0.2	-0.5	-1.2	-0.8	0.5	-0.7	-1.3	-0.9	-1.2	-0.5	1.2	-1.7	-0.7	0.3
Whole body fat-free mass	0.4	2.4	18.3	-0.1	-0.9	-1.0	-0.8	-0.9	-1.8	-1.4	-4.3	-1.4	-0.4	-1.3	-0.6	-1.0	2.8	-0.6	-1.2	0.4
Ever had bowel cancer screening	0.4	0.4	3.3	-0.4	-0.3	-0.4	-0.4	-0.4	0.4	-0.7	-1.8	-0.6	0.1	-0.0	0.3	-0.6	-1.1	-0.5	-0.5	-0.4
Medication for cholesterol	0.4	0.6	4.9	0.2	-0.4	-0.2	0.1	0.0	-1.3	-0.7	0.7	-0.8	-1.0	0.1	0.1	-0.4	-2.2	-0.2	-1.0	-0.5
Medication: Aspirin	0.4	0.5	1.3	0.3	0.5	0.3	0.6	0.5	1.1	0.7	1.1	0.7	0.5	0.5	0.4	0.5	-0.8	0.5	1.2	0.7
Smoking status: Current	0.4	0.6	1.9	0.6	0.5	0.5	1.0	0.4	1.4	0.9	0.9	0.7	0.9	0.5	0.9	0.6	1.1	0.1	0.1	0.0
Whole body water mass	0.4	2.3	18.5	-0.1	-0.9	-1.0	-0.8	-0.9	-1.6	-1.3	-4.3	-1.3	-0.3	-1.2	-0.5	-1.0	2.7	-0.6	-1.1	0.5
Pain type(s) experienced in last month: Hip pain	0.4	0.6	1.9	-1.1	-0.7	-0.8	-1.0	-0.6	0.2	-0.6	-1.4	-0.4	-0.3	-0.5	-0.4	-0.7	-1.2	0.0	-0.5	-0.7
Medication: Paracetamol	0.4	0.6	1.3	0.0	0.6	0.6	0.4	0.8	0.8	0.6	-0.8	0.7	1.1	0.8	1.0	0.4	0.9	0.8	0.7	1.1
Cholesterol lowering medication	0.4	0.5	2.1	0.7	0.6	0.5	0.4	0.4	0.7	0.6	0.9	0.7	1.0	0.4	-0.1	0.6	1.5	1.0	1.1	0.2
Alzheimer’s Disease (in father)	0.3	0.4	1.5	0.1	0.4	0.3	0.4	0.4	1.2	0.5	0.2	0.5	0.6	0.5	1.2	0.3	-0.0	0.9	0.7	0.4
Irritable Bowel Disease (IBD)	0.3	0.7	1.3	-1.2	-1.1	-1.0	-0.6	-1.0	0.2	-1.0	-0.3	-0.8	-0.6	-0.9	-0.7	-1.1	-0.8	-0.4	-0.7	-1.1
Breast Cancer	0.3	0.6	8.4	-0.4	0.3	0.2	-0.1	0.1	0.0	0.3	2.9	0.4	-0.1	-0.2	-0.4	0.2	1.1	0.1	0.1	-0.5
Coronary Artery Disease (CAD)	0.3	0.3	1.6	-0.7	-0.3	-0.4	-0.2	-0.6	-0.1	-0.1	0.5	-0.2	-0.1	-0.5	-0.8	-0.3	1.3	-0.5	-0.3	-0.9
Blood White Count	0.3	2.1	3.5	-1.1	-1.6	-1.8	-1.9	-1.7	-0.2	-1.3	1.3	-1.3	-0.8	-1.6	-1.7	-1.6	1.7	-1.3	-0.4	-1.9
BMI	0.3	1.7	4.7	-1.0	-1.3	-1.4	-1.1	-1.2	-1.7	-1.6	-2.2	-1.6	-1.0	-1.2	-0.8	-1.4	-0.8	0.1	-1.4	-1.3
Lung FEV1/FVC ratio	0.3	1.6	13.6	0.9	0.6	1.0	0.5	0.9	0.4	1.1	3.7	1.1	-0.1	0.9	0.2	0.9	-1.4	1.6	1.5	0.2
Sensitivity / hurt feelings	0.3	0.5	1.3	0.6	0.3	0.5	0.5	0.5	1.1	0.6	0.4	0.6	0.8	0.7	1.0	0.5	-0.1	1.1	1.1	0.8
Medication: Co-codamol	0.3	0.4	1.6	-1.1	-0.5	-0.7	-0.5	-0.6	-0.3	-0.3	-0.2	-0.4	-0.1	-0.5	-0.2	-0.7	1.3	0.5	-0.2	-1.1
Serious illness, injury or assault to yourself	0.3	0.3	1.1	0.6	0.5	0.6	0.3	0.5	0.1	0.5	-0.4	0.8	0.4	0.3	0.3	0.6	-1.0	1.0	0.3	0.4
Supplements: Glucosamine	0.3	0.3	2.1	-0.3	0.3	0.3	0.6	0.1	1.0	0.3	-0.2	0.7	0.8	0.2	0.6	0.3	-0.1	1.5	0.5	-0.2
Medication: Levothyroxine sodium	0.3	0.5	2.0	0.2	-0.1	-0.0	-0.3	0.1	-1.4	-0.2	1.2	-0.4	-0.5	-0.2	-1.1	-0.1	1.2	-1.0	-0.5	-0.8
Chronic bronchitis/emphysema (father)	0.3	0.3	1.3	1.1	0.3	0.5	0.4	0.5	-0.4	0.0	0.9	-0.1	0.3	0.6	0.1	0.2	0.0	1.1	0.8	0.3
Hearing difficulty/problems with background noise	0.3	0.5	1.4	-0.8	-0.7	-0.7	-1.2	-0.7	0.2	-0.2	-1.0	-0.6	-0.1	-0.7	-0.3	-0.6	0.9	-0.9	-0.5	-0.6
Ever unenthusiastic/disinterested for a whole week	0.3	0.3	2.0	-0.1	-0.3	-0.1	-0.3	-0.0	-1.4	-0.6	-0.8	-0.4	-0.6	-0.1	-0.6	-0.3	0.2	-0.7	-0.9	-0.2
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.4	1.9	0.4	0.4	0.5	0.6	0.4	-1.2	0.5	0.9	0.4	-0.6	-0.0	-0.3	0.5	0.1	-1.4	-0.8	0.2
Length of working week for main job	0.3	0.3	1.4	-0.1	-0.5	-0.5	-0.4	-0.4	-0.8	-0.3	1.2	-0.4	-1.1	-0.5	-0.9	-0.4	-0.4	-0.5	0.2	-0.2
Hypothyroidism/myxoedema (self-reported)	0.3	0.5	3.6	1.0	0.4	0.4	0.3	0.5	-0.9	0.2	1.9	0.1	-0.0	0.2	-0.6	0.3	1.7	-0.2	0.1	-0.1
Age at first live birth	0.3	0.5	1.7	-0.5	-0.8	-0.7	-0.8	-0.9	-0.5	-0.9	0.1	-1.0	-0.6	-0.7	-0.6	-0.9	0.5	-1.3	-0.2	-0.6
Medication: Omeprazole	0.3	0.3	1.3	-0.0	-0.2	-0.2	-0.6	-0.1	1.1	-0.0	-1.1	0.1	0.8	0.1	0.5	-0.1	0.2	0.5	1.0	0.2
Comparative height size at age 10	0.3	1.5	2.9	-1.1	-1.6	-1.3	-1.4	-1.2	-0.8	-1.5	-1.6	-0.9	-1.7	-1.6	-1.1	-1.4	-0.4	-0.9	-0.4	0.3
Suffer from ‘nerves’	0.3	0.4	1.7	0.0	0.6	0.5	1.0	0.5	0.4	0.9	1.3	0.9	0.2	0.3	0.3	0.6	0.2	0.8	0.7	0.7
Overall health rating	0.3	0.5	2.8	0.1	0.3	0.3	0.6	0.7	0.8	0.4	1.1	0.6	0.4	0.7	0.5	0.3	-1.7	1.0	0.8	0.7
Supplements: Vitamin C	0.3	0.3	1.3	0.3	0.5	0.6	0.6	0.6	-1.2	0.3	0.5	0.1	0.5	0.7	0.1	0.3	0.8	0.7	-0.3	-0.1
Mineral and other dietary supplements	0.3	0.4	1.5	0.1	-0.5	-0.6	-0.5	-0.4	-0.8	-0.2	1.2	-0.5	-0.8	-0.5	-0.9	-0.3	0.7	-0.7	-0.2	-0.2
Supplements: Fish oil (including cod liver oil)	0.3	0.4	2.7	-0.6	0.1	0.2	-0.1	0.0	1.0	-0.0	-1.6	0.2	0.5	0.3	0.8	0.0	-0.9	0.6	0.3	0.0
Medication: Omeprazole (e.g. Zanprol)	0.3	0.4	1.2	-0.3	-0.4	-0.5	-0.9	-0.4	1.0	-0.3	-0.8	-0.3	0.9	-0.2	0.3	-0.5	1.1	0.4	0.8	-0.2
Pain experienced in last month	0.3	0.6	5.0	0.0	-0.5	-0.3	-0.1	-0.4	-1.0	-0.7	-0.3	-0.7	-0.4	-0.6	-0.8	-0.4	2.2	-0.7	-0.6	0.1
Alcohol drinker status: Previous	0.3	0.3	2.0	-0.2	0.0	-0.0	0.2	0.0	0.6	0.1	-1.1	0.4	0.5	0.1	0.5	0.1	-0.9	1.4	0.4	0.2
Arm predicted mass (left)	0.3	1.3	12.3	1.4	0.5	0.5	0.6	0.6	-0.4	0.4	-0.7	0.2	0.9	0.2	0.4	0.5	3.5	1.1	1.0	1.4
Verbal and Numeric Reasoning (VNR)	0.2	0.4	1.0	0.8	0.9	0.8	0.7	0.5	0.4	0.7	0.7	0.7	0.5	0.6	1.0	0.8	-0.5	-0.4	0.2	-0.1
Body Mass Index (BMI) (2010)	0.2	0.3	0.5	-0.3	-0.3	-0.3	-0.5	-0.6	-0.4	-0.7	-0.5	-0.6	-0.6	-0.5	-0.7	-0.5	-0.2	-0.7	-0.5	-0.4
Crohns Disease (2012)	0.2	0.3	1.0	0.4	0.5	0.4	0.6	0.3	0.3	0.3	1.0	0.6	-0.4	0.5	-0.1	0.5	-0.8	-0.1	0.6	0.6
Lupus	0.2	0.3	1.6	0.1	0.4	0.4	0.5	0.1	0.7	0.6	0.4	0.6	0.7	0.3	0.5	0.4	1.3	0.5	0.2	0.0
Rheumatoid Arthritis	0.2	0.3	1.1	-0.0	-0.8	-0.6	-0.2	-0.4	0.0	-0.8	-1.0	-0.6	0.1	-0.2	-0.1	-0.6	-0.8	0.5	-0.2	-0.1
Schizophrenia (2014)	0.2	0.5	6.1	-0.0	-0.1	-0.2	-0.5	-0.2	-0.1	0.3	0.1	-0.1	0.2	-0.0	-0.1	-0.1	2.5	-1.1	0.3	0.4
Triglycerides	0.2	0.3	2.6	-0.1	-0.3	-0.3	-0.4	-0.5	0.2	-0.3	0.9	-0.1	-0.3	-0.6	-0.4	-0.3	1.6	0.3	0.4	-0.1
Ulcerative Colitis	0.2	0.3	1.7	-0.6	-0.5	-0.5	0.1	-0.2	0.6	-0.4	0.3	-0.3	-0.1	0.0	-0.5	-0.5	-1.3	0.7	-0.2	-0.3
Blood Eosinophil Count	0.2	1.4	7.0	0.7	0.5	0.6	0.4	0.9	1.7	0.7	2.6	0.8	1.6	1.1	1.0	0.5	0.1	1.4	1.8	-0.1
Tanning	0.2	2.4	3.7	-1.8	-1.6	-1.7	-1.9	-1.6	-1.3	-1.9	-1.7	-1.7	-1.6	-1.4	-1.6	-1.8	-0.6	-0.9	-1.4	-0.9
Hearing difficulty/problems: Yes	0.2	0.3	1.4	-1.2	-0.4	-0.5	-0.9	-0.6	0.6	-0.0	-0.7	-0.2	0.0	-0.4	0.3	-0.4	0.4	-0.6	-0.8	-0.7
Relative age of first facial hair	0.2	0.4	2.6	0.7	0.6	0.6	-0.0	0.6	-0.1	0.6	0.6	0.4	0.6	0.6	0.4	0.4	1.6	-0.4	0.6	0.4
Pack years adult smoking proportion	0.2	0.3	2.1	0.5	0.5	0.4	0.8	0.5	0.4	0.5	1.4	0.5	0.4	0.5	-0.1	0.5	-0.4	0.6	0.0	0.0
Current tobacco smoking	0.2	0.3	1.5	0.3	0.3	0.3	0.7	0.2	1.0	0.6	0.6	0.4	0.7	0.3	0.7	0.4	1.2	-0.2	-0.3	-0.1
Average weekly fortified wine intake	0.2	0.2	1.2	0.3	-0.3	-0.4	0.1	-0.5	-0.1	-0.4	-1.0	-0.2	-0.4	-0.6	-0.1	-0.2	-1.1	0.2	-0.3	-0.5
Body mass index (BMI)	0.2	0.9	2.7	-0.6	-0.9	-1.1	-0.9	-0.7	-1.6	-1.3	-0.9	-1.4	-1.0	-0.8	-0.9	-1.1	0.1	-0.2	-0.9	-0.6
Number of incorrect matches in round	0.2	0.3	1.4	0.3	-0.6	-0.5	-0.3	-0.3	-1.2	-0.8	-0.7	-1.0	-0.5	-0.3	-0.3	-0.6	0.1	0.0	-0.1	-0.4
Past tobacco smoking	0.2	0.4	1.0	-0.4	-0.7	-0.7	-0.1	-0.8	-0.5	-1.0	-0.4	-0.8	-0.3	-0.9	-1.0	-0.7	0.6	0.2	-0.6	-0.6
Medication: Simvastatin	0.2	0.3	2.1	-0.5	0.1	-0.1	-0.2	-0.0	1.1	0.2	1.4	0.5	0.3	0.1	-0.1	-0.0	0.1	0.3	1.0	-0.4
Illnesses of siblings	0.2	0.3	1.9	0.3	0.0	0.2	0.2	0.4	-1.4	-0.1	0.3	-0.2	-0.8	-0.0	-0.7	0.1	-0.6	-0.4	-0.4	0.6
Neuroticism score	0.2	0.3	2.6	-0.6	-0.3	-0.3	0.1	-0.1	0.3	-0.1	1.1	0.1	-0.5	-0.1	-0.1	-0.2	-1.6	0.8	0.1	-0.2
Trunk fat-free mass	0.2	1.1	10.0	0.9	0.1	-0.0	0.2	0.0	-0.9	-0.3	-2.4	-0.3	0.3	-0.4	-0.1	-0.0	3.2	0.1	0.0	1.2
Falls in the last year	0.2	0.3	0.9	-0.7	-0.3	-0.5	-0.6	-0.3	-0.3	-0.4	0.6	-0.4	-0.2	-0.3	-0.9	-0.5	0.2	-0.6	-0.6	-0.9
Noisy workplace	0.2	0.2	1.4	-0.0	0.4	0.4	-0.2	0.3	0.0	0.6	0.5	0.3	0.5	0.3	0.6	0.3	1.2	0.5	0.3	-0.2
Trunk predicted mass	0.2	1.1	10.1	0.9	0.0	-0.1	0.1	-0.0	-0.9	-0.3	-2.4	-0.3	0.3	-0.4	-0.1	-0.0	3.2	0.0	0.0	1.1
Breastfed as a baby	0.2	0.2	0.4	-0.5	-0.2	-0.3	-0.3	-0.4	-0.5	-0.6	-0.6	-0.6	-0.2	-0.3	-0.2	-0.5	0.1	0.2	-0.6	-0.7
Blood clot in the leg (DVT)	0.2	0.3	3.2	0.2	0.2	0.1	0.2	0.1	0.3	-0.0	-1.8	0.2	0.1	0.1	0.1	0.1	-1.1	-0.2	-0.6	0.5
Arm fat-free mass (right)	0.2	1.2	12.3	1.4	0.5	0.5	0.6	0.6	-0.4	0.4	-1.1	0.2	0.9	0.2	0.4	0.4	3.5	0.5	0.8	1.3
Seen a psychiatrist for nerves, anxiety, tension or depression	0.2	0.2	0.6	-0.4	-0.4	-0.5	-0.4	-0.5	-0.2	-0.3	-0.3	-0.5	-0.1	-0.6	-0.6	-0.4	0.5	-0.6	-0.4	-0.8
Mouth/teeth dental problems: Loose teeth	0.2	0.2	1.2	-0.5	0.3	0.3	-0.1	-0.0	0.3	0.5	-0.3	0.4	0.7	0.1	0.1	0.3	1.1	0.1	-0.5	-0.3
Medication for pain relief, constipation, heartburn	0.2	0.3	0.9	-0.3	-0.6	-0.4	-0.5	-0.7	-0.5	-0.7	-0.1	-0.6	-1.0	-0.6	-0.7	-0.4	-0.2	0.1	-0.4	-0.8
Arm predicted mass (right)	0.2	1.1	10.7	1.3	0.5	0.5	0.7	0.6	-0.5	0.4	-1.0	0.2	0.9	0.3	0.3	0.4	3.3	0.5	0.7	1.2
Number of full sisters	0.2	0.2	1.0	0.0	0.4	0.3	0.0	0.5	-0.0	0.4	0.9	0.3	0.3	0.4	0.6	0.2	0.1	1.0	0.8	0.5
Age at last live birth	0.2	0.3	0.7	0.4	0.6	0.6	0.6	0.2	0.8	0.5	0.2	0.5	0.6	0.6	0.7	0.5	0.3	-0.6	0.5	0.3
Smoking status: Previous	0.2	0.3	0.8	0.3	0.5	0.6	-0.1	0.7	-0.0	0.6	0.0	0.6	0.1	0.7	0.7	0.5	-0.9	-0.0	0.6	0.5
Mood swings	0.2	0.4	3.8	-0.0	0.1	0.2	0.5	0.2	0.6	0.4	0.8	0.7	-0.1	0.3	0.3	0.4	-1.9	-0.1	-0.3	-0.1
Loneliness, isolation	0.2	0.3	3.4	-0.4	0.0	-0.0	0.2	0.2	0.3	-0.1	-0.2	0.4	0.1	0.1	-0.1	0.1	-1.8	1.3	-0.1	0.3
Friendships satisfaction	0.2	0.2	1.5	-0.8	-0.2	-0.2	0.0	-0.2	0.2	0.0	1.2	-0.0	-0.0	-0.3	-0.6	-0.2	0.3	-0.3	-0.4	-0.8
Number of self-reported non-cancer illnesses	0.2	0.3	1.9	-0.6	0.3	0.1	0.1	0.5	0.6	0.3	0.0	0.6	0.7	0.4	0.3	0.1	-0.9	1.4	0.5	-0.1
Miserableness	0.2	0.4	1.7	-0.2	0.3	0.3	0.6	0.5	0.2	0.3	0.9	0.5	0.4	0.5	0.7	0.2	-1.3	1.3	-0.0	-0.0
Medication: Atorvastatin	0.2	0.3	2.8	0.0	-0.3	-0.3	-0.3	-0.2	-0.6	-0.1	0.9	-0.5	-0.1	-0.2	-0.4	-0.4	1.7	-0.4	0.1	-0.2
Arm fat-free mass (left)	0.2	1.0	12.4	1.2	0.2	0.1	0.2	0.2	-0.6	0.0	-1.0	-0.2	0.6	-0.1	0.0	0.1	3.5	0.7	0.7	1.0
Deep venous thrombosis (DVT) (self-reported)	0.2	0.2	3.0	0.1	0.1	0.1	-0.0	0.0	0.4	0.0	-1.7	0.2	0.1	0.2	0.1	0.1	-0.6	-0.0	-0.5	0.3
Bipolar Disorder (2018)	0.1	0.2	1.1	0.4	0.3	0.4	0.6	0.1	0.1	0.7	1.1	0.6	0.2	0.1	0.0	0.5	-0.1	0.3	0.5	-0.0
Bipolar Disorder or Schizophrenia	0.1	0.3	1.5	0.5	0.4	0.3	0.4	0.2	-0.0	0.9	0.7	0.6	0.3	0.2	0.1	0.5	1.2	-0.5	0.5	0.4
Depressed Affect (Nagel 2018)	0.1	0.2	1.3	-0.6	-0.2	-0.3	-0.1	-0.1	0.6	-0.1	0.3	0.3	0.0	-0.1	0.1	-0.2	-1.1	0.8	-0.4	-0.4
Depression (Nagel 2018)	0.1	0.1	0.7	-0.6	-0.0	-0.2	0.1	-0.2	0.0	0.0	0.5	-0.0	-0.0	-0.3	-0.5	-0.1	-0.5	-0.4	-0.9	-0.4
Neuroticism (Nagel 2018)	0.1	0.2	1.0	-0.6	-0.4	-0.5	-0.3	-0.2	0.4	-0.2	-0.1	-0.1	-0.1	-0.3	-0.1	-0.4	-1.0	0.3	-0.3	-0.3
Schizophrenia (2018)	0.1	0.3	2.7	0.3	0.2	0.1	0.0	0.1	-0.2	0.5	-0.0	0.3	0.2	0.2	0.1	0.2	1.6	-0.9	0.3	0.6
Worry (Nagel 2018)	0.1	0.3	0.6	-0.7	-0.6	-0.7	-0.5	-0.5	0.1	-0.2	0.4	-0.3	-0.7	-0.7	-0.5	-0.5	-0.7	-0.2	-0.1	-0.3
Crohns Disease (2017)	0.1	0.3	1.7	0.3	0.6	0.6	0.8	0.5	0.4	0.5	1.3	0.8	0.2	0.5	0.1	0.6	-0.1	-0.4	0.3	0.3
Ovarian Cancer	0.1	0.1	0.7	0.1	-0.0	0.0	-0.7	-0.2	0.2	0.0	0.6	0.0	0.1	-0.2	0.0	0.1	0.6	-0.8	-0.1	-0.2
Neuroticism (2016)	0.1	0.2	1.3	-0.0	-0.0	-0.2	0.3	-0.0	0.6	0.3	1.1	0.4	0.1	-0.4	-0.1	0.2	0.7	-0.0	0.3	0.4
Primary Biliary Cirrhosis	0.1	0.2	1.5	-0.2	-0.3	-0.2	-0.3	-0.1	0.1	-0.1	-0.7	0.0	0.3	-0.0	-0.0	-0.2	0.7	1.2	0.7	0.0
Townsend deprivation index at recruitment	0.1	0.1	0.2	0.1	0.3	0.2	0.3	0.2	-0.4	0.0	0.3	0.1	0.3	0.2	-0.3	0.2	-0.2	0.4	-0.5	-0.4
Fed-up feelings	0.1	0.2	1.1	-0.4	0.2	-0.0	0.5	0.2	0.4	0.2	0.7	0.5	0.1	0.2	-0.3	0.2	-0.8	1.1	-0.3	0.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.1	0.2	1.1	0.3	0.4	0.2	0.6	0.3	0.4	0.2	1.0	0.3	0.5	0.3	-0.1	0.3	-0.6	0.1	-0.2	0.4
Taking other prescription medications	0.1	0.2	1.4	-0.0	0.3	0.1	0.1	0.5	-0.5	0.2	0.4	0.4	0.1	0.2	0.0	0.2	-1.2	0.6	-0.0	-0.4
Nervous feelings	0.1	0.2	0.7	-0.8	-0.2	-0.3	0.2	-0.3	0.5	0.2	0.7	0.2	-0.2	-0.3	-0.1	-0.2	-0.3	0.9	0.3	0.1
Fluid intelligence score	0.1	0.2	0.9	0.0	0.2	0.1	0.1	0.0	-0.2	-0.0	0.8	-0.1	-0.4	0.2	0.3	0.1	-0.8	-1.0	-0.3	-0.3
Father’s age at death	0.1	0.1	0.5	0.0	0.2	0.2	0.2	0.3	-0.6	0.2	-0.7	0.1	0.2	0.3	-0.1	0.1	0.5	0.6	-0.4	0.0
Asthma	0.1	0.1	0.3	-0.3	-0.4	-0.4	-0.1	-0.3	-0.4	-0.4	0.5	-0.3	-0.5	-0.3	-0.2	-0.4	0.6	0.0	0.1	-0.2
Lung cancer (father)	0.1	0.1	0.8	0.3	0.0	0.2	0.1	0.1	0.2	-0.0	-0.9	-0.1	0.2	0.1	0.8	0.1	-0.4	0.3	0.0	0.1
Tense / ‘highly strung’	0.1	0.2	1.4	-0.2	-0.2	-0.3	-0.1	-0.3	1.2	0.3	-0.0	0.4	0.2	-0.2	0.7	0.1	-1.1	-0.5	0.3	-0.0
Seen doctor (GP) for nerves, anxiety, tension or depression	0.1	0.1	0.9	0.1	0.4	0.3	0.3	0.3	-0.5	0.2	-0.3	0.4	0.4	0.1	-0.1	0.3	-0.5	0.9	-0.3	-0.2
Comparative body size at age 10	0.1	0.3	2.2	-0.2	0.1	-0.1	-0.1	-0.1	-1.5	-0.3	-1.0	-0.5	-0.1	-0.2	-0.1	-0.2	0.4	0.5	-1.0	-0.8
Number of full brothers	0.1	0.2	0.9	-0.2	-0.3	-0.3	-0.5	-0.2	-0.2	-0.0	-1.0	-0.1	0.2	-0.1	0.3	-0.2	-0.8	-0.1	-0.3	-0.5
Medication: Allopurinol	0.1	0.1	1.2	-0.3	-0.3	-0.4	0.0	-0.2	0.7	0.0	0.1	-0.0	0.3	-0.2	-0.1	-0.3	1.1	0.1	0.4	-0.1
Chest pain or discomfort	0.1	0.1	0.5	-0.7	-0.4	-0.4	-0.1	-0.4	0.5	-0.1	0.2	-0.1	-0.1	-0.4	0.2	-0.4	0.5	0.5	0.3	-0.1
Qualifications: NVQ or HND or HNC or equivalent	0.1	0.1	0.9	-0.5	0.2	0.2	0.2	0.2	-0.9	0.3	0.4	0.1	-0.1	0.2	-0.1	0.2	0.2	-0.6	-0.3	-0.2
Handedness (chirality/laterality): Left-handed	0.1	0.1	0.4	0.3	0.2	0.3	0.3	0.5	-0.6	-0.1	0.5	-0.0	0.3	0.4	0.4	0.2	0.2	0.7	-0.2	-0.3
Asthma (self-reported)	0.1	0.3	0.4	-0.5	-0.6	-0.6	-0.3	-0.4	-0.6	-0.6	0.5	-0.5	-0.7	-0.5	-0.4	-0.6	0.5	0.0	-0.0	-0.4
Osteoarthritis (self-reported)	0.1	0.2	1.1	-0.4	-0.0	-0.1	0.1	-0.1	1.1	-0.1	-0.4	0.3	0.3	0.0	0.6	-0.0	-0.7	0.4	0.4	0.3
Ever taken oral contraceptive pill	0.1	0.1	0.5	-0.4	-0.1	-0.2	-0.5	-0.1	0.0	-0.3	0.7	-0.3	0.0	-0.1	-0.4	-0.2	0.3	-0.2	-0.1	-0.5
Alcohol drinker status: Never	0.1	0.1	0.5	-0.2	0.1	-0.1	0.2	0.1	-0.1	-0.1	0.4	-0.0	-0.0	0.1	-0.3	-0.1	-0.4	0.7	-0.2	-0.3
Ever smoked	0.1	0.2	0.5	-0.0	0.4	0.5	0.0	0.5	0.1	0.6	0.7	0.4	0.2	0.7	0.5	0.4	0.2	-0.5	-0.1	0.0
Irritability	0.1	0.1	0.7	0.3	0.2	0.1	0.1	0.2	0.8	0.3	-0.2	0.3	0.6	0.4	0.5	0.3	-0.3	-0.3	0.2	-0.3
Risk taking	0.1	0.1	0.8	-0.3	-0.1	-0.1	-0.3	-0.2	0.0	0.0	-0.7	-0.1	0.2	-0.0	-0.1	-0.1	0.9	-0.3	-0.2	-0.2
Pack years of smoking	0.1	0.2	1.8	0.4	0.3	0.1	0.6	0.3	0.0	0.2	1.3	0.1	0.3	0.4	-0.2	0.2	-0.2	0.5	0.0	-0.1
HDL Cholesterol	0.0	0.0	0.2	0.3	-0.2	-0.1	0.3	0.1	0.1	-0.1	-0.5	-0.2	0.1	0.1	-0.1	-0.0	-0.0	-0.1	0.0	0.4
Hair Pigment	0.0	0.6	4.3	-0.5	-0.3	-0.1	-0.1	-0.2	-0.9	-0.3	2.1	-0.5	-1.0	-0.2	-0.6	-0.5	-1.0	-0.7	0.0	-0.8
Age when periods started (menarche)	0.0	0.1	0.7	0.1	-0.3	-0.1	-0.1	-0.2	0.8	-0.1	-0.1	-0.0	-0.1	0.0	0.1	-0.1	-0.2	0.5	0.6	0.3
Hair/balding pattern: Pattern 4	0.0	0.1	0.3	-0.3	-0.2	-0.1	0.2	0.0	0.5	-0.1	-0.0	-0.0	0.3	0.2	0.1	-0.2	0.6	0.0	0.1	-0.1

Hub : Genes

FBN2

Models

Trait associations