Best TWAS P=1.98e-08 · Best GWAS P=4.79e-08 conditioned to 0.282
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | ZDHHC4 | 0.29 | 0.09 | enet | 19 | 0.13 | 7.5e-08 | 4.3 | -5.6 | 2.0e-08 | 0.42 | 0.44 | 0.49 | TRUE |
| 2 | GTEx | Nerve Tibial | PMS2CL | 0.19 | 0.04 | enet | 10 | 0.08 | 2.0e-06 | 3.9 | -5.2 | 1.8e-07 | 0.52 | 0.14 | 0.79 | FALSE |
| 3 | GTEx | Thyroid | PMS2CL | 0.10 | 0.07 | lasso | 3 | 0.07 | 6.5e-06 | 5.0 | -5.3 | 1.4e-07 | 0.42 | 0.06 | 0.92 | TRUE |