Best TWAS P=4.47e-08 · Best GWAS P=1.16e-06 conditioned to 0.752
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Brain Cortex | LY6K | 0.50 | 0.45 | enet | 36 | 0.42 | 1.0e-12 | 4.7 | -5.5 | 4.5e-08 | -0.86 | 0.02 | 0.97 | TRUE |
2 | GTEx | Brain Nucleus accumbens basal ganglia | LY6K | 0.52 | 0.44 | enet | 24 | 0.41 | 3.5e-12 | 4.7 | -5.2 | 2.2e-07 | -0.94 | 0.02 | 0.97 | FALSE |