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chr9:14,857,740-16,758,776

Best TWAS P=4.92e-31 · Best GWAS P=2.57e-26 conditioned to 0.673

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Artery Aorta	CCDC171	0.18	0.05	lasso	5	0.08	2.2e-05	-3.2	-5.3	1.4e-07	0.31	0.34	0.06	FALSE
2	GTEx	Artery Tibial	CCDC171	0.10	0.09	enet	9	0.12	7.2e-10	4.6	-5.9	3.4e-09	0.60	0.93	0.07	FALSE
3	GTEx	Brain Caudate basal ganglia	CCDC171	0.30	0.18	lasso	4	0.23	2.4e-07	8.7	-9.9	3.4e-23	0.95	0.03	0.97	FALSE
4	GTEx	Brain Cerebellar Hemisphere	CCDC171	0.46	0.19	lasso	7	0.23	1.3e-06	-10.6	-11.6	4.9e-31	0.91	0.02	0.98	TRUE
5	GTEx	Brain Cerebellum	CCDC171	0.46	0.22	lasso	7	0.15	3.4e-05	-9.9	-10.6	3.1e-26	0.97	0.01	0.98	FALSE
6	GTEx	Brain Cortex	CCDC171	0.26	0.15	lasso	2	0.16	2.8e-05	-8.6	-9.3	1.1e-20	0.92	0.04	0.94	FALSE
7	GTEx	Brain Frontal Cortex BA9	CCDC171	0.27	0.18	enet	10	0.19	8.3e-06	9.0	-8.6	5.8e-18	0.83	0.06	0.90	FALSE
8	GTEx	Brain Hypothalamus	CCDC171	0.32	0.17	enet	6	0.09	4.0e-03	-10.6	-8.8	1.8e-18	0.91	0.02	0.94	FALSE
9	GTEx	Breast Mammary Tissue	CCDC171	0.21	0.01	lasso	5	0.03	1.5e-02	7.8	-5.1	2.7e-07	0.55	0.35	0.24	FALSE
10	GTEx	Lung	CCDC171	0.13	0.03	enet	9	0.01	5.0e-02	6.3	-7.9	3.0e-15	0.72	0.54	0.15	FALSE
11	GTEx	Nerve Tibial	CCDC171	0.25	0.16	lasso	6	0.14	2.1e-10	-9.8	-9.8	7.0e-23	0.96	0.15	0.85	FALSE
12	GTEx	Ovary	CCDC171	0.21	0.19	lasso	4	0.16	7.7e-05	8.7	8.3	9.3e-17	-0.85	0.25	0.23	FALSE
13	GTEx	Pituitary	CCDC171	0.28	0.16	enet	29	0.12	5.2e-04	8.8	-9.3	1.3e-20	0.90	0.16	0.79	FALSE
14	GTEx	Skin Not Sun Exposed Suprapubic	CCDC171	0.20	0.04	enet	45	0.06	4.9e-04	8.8	-5.1	3.0e-07	0.40	0.59	0.31	FALSE
15	GTEx	Skin Sun Exposed Lower leg	CCDC171	0.14	0.09	enet	13	0.12	1.9e-10	8.7	-6.5	6.2e-11	0.63	0.99	0.01	FALSE
16	METSIM	Adipose	CCDC171	0.03	0.00	blup	828	0.01	4.0e-02	8.9	-8.4	3.8e-17	0.79	0.18	0.62	FALSE
17	ROSMAP	Brain Pre-frontal Cortex	CCDC171	0.14	0.11	enet	21	0.11	8.3e-14	8.9	-9.4	3.8e-21	0.81	0.98	0.02	FALSE
18	The Cancer Genome Atlas	Soft Tissue Sarcoma	C9orf93	0.06	0.05	lasso	3	0.03	5.3e-03	7.9	-6.7	2.3e-11	0.70	0.15	0.16	TRUE