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chr11:61,664,757-63,110,149

Best TWAS P=6.91e-08 · Best GWAS P=1.52e-07 conditioned to 0.543

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	ROM1	0.25	0.17	lasso	3	0.18	1.5e-14	-5.2	5.3	9.3e-08	-0.99	0.01	0.98	FALSE
2	GTEx	Cells Transformed fibroblasts	EML3	0.19	0.16	lasso	9	0.18	7.3e-14	-5.0	-5.3	1.3e-07	0.92	0.02	0.98	FALSE
3	GTEx	Esophagus Mucosa	MTA2	0.29	0.34	lasso	5	0.33	6.9e-23	-5.1	-5.1	2.8e-07	0.95	0.02	0.98	FALSE
4	GTEx	Lung	ROM1	0.25	0.18	enet	13	0.20	2.2e-15	-5.2	5.3	9.1e-08	-0.96	0.02	0.98	FALSE
5	GTEx	Nerve Tibial	EML3	0.17	0.10	lasso	4	0.09	3.9e-07	-5.2	-5.1	2.8e-07	0.95	0.02	0.98	FALSE
6	GTEx	Ovary	ROM1	0.25	0.00	lasso	5	0.00	3.3e-01	-5.0	5.2	2.0e-07	-0.93	0.02	0.75	FALSE
7	GTEx	Skin Not Sun Exposed Suprapubic	B3GAT3	0.18	0.11	lasso	3	0.11	9.8e-07	-4.9	-5.3	1.4e-07	0.80	0.02	0.97	FALSE
8	GTEx	Skin Sun Exposed Lower leg	ROM1	0.13	0.11	lasso	4	0.10	9.7e-09	-5.2	5.2	1.8e-07	-0.95	0.02	0.98	FALSE
9	GTEx	Skin Sun Exposed Lower leg	EML3	0.32	0.25	enet	19	0.26	8.0e-22	-5.2	-5.4	8.0e-08	0.93	0.02	0.98	FALSE
10	GTEx	Stomach	EML3	0.11	0.04	enet	5	0.03	2.1e-02	-5.2	-5.4	6.9e-08	0.93	0.02	0.86	TRUE
11	GTEx	Testis	EML3	0.27	0.22	enet	15	0.29	2.7e-13	-5.1	-5.3	1.4e-07	0.95	0.02	0.98	FALSE
12	GTEx	Thyroid	ROM1	0.17	0.16	lasso	8	0.16	3.6e-12	-5.1	5.2	1.8e-07	-0.98	0.02	0.98	FALSE
13	GTEx	Thyroid	EML3	0.10	0.11	lasso	4	0.10	5.9e-08	-5.2	-5.2	2.5e-07	0.95	0.02	0.98	FALSE
14	YFS	Blood	EML3	0.20	0.31	lasso	12	0.33	1.3e-110	-5.1	-5.1	2.9e-07	0.98	0.02	0.98	FALSE
15	YFS	Blood	INTS5	0.09	0.12	lasso	4	0.12	1.9e-38	-4.9	-5.2	1.7e-07	0.82	0.04	0.96	FALSE
16	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	EEF1G	0.04	0.05	lasso	1	0.04	1.1e-04	-5.2	5.2	1.5e-07	-1.00	0.01	0.96	FALSE
17	The Cancer Genome Atlas	Breast Invasive Carcinoma	EML3	0.02	0.02	lasso	4	0.02	2.5e-05	-5.1	-5.2	2.6e-07	0.98	0.02	0.98	FALSE
18	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	EML3	0.04	0.06	lasso	3	0.06	1.7e-07	-5.2	-5.2	2.5e-07	0.95	0.02	0.98	FALSE
19	The Cancer Genome Atlas	Brain Lower Grade Glioma	EEF1G	0.06	0.07	blup	27	0.07	8.1e-09	-4.9	5.2	2.5e-07	-0.92	0.02	0.98	FALSE
20	The Cancer Genome Atlas	Brain Lower Grade Glioma	EML3	0.03	0.04	blup	28	0.03	7.6e-05	-5.1	-5.3	1.1e-07	0.95	0.01	0.98	FALSE
21	The Cancer Genome Atlas	Lung Adenocarcinoma	EEF1G	0.06	0.08	lasso	8	0.08	5.9e-10	-4.9	5.1	3.0e-07	-0.92	0.02	0.98	FALSE
22	The Cancer Genome Atlas	Lung Adenocarcinoma	EML3	0.03	0.03	blup	28	0.03	8.4e-05	-4.9	-5.2	2.4e-07	0.96	0.02	0.98	FALSE
23	The Cancer Genome Atlas	Lung Adenocarcinoma	ROM1	0.04	0.04	blup	23	0.04	9.5e-06	-4.9	5.2	2.0e-07	-0.95	0.01	0.99	FALSE
24	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	C11orf83	0.07	0.01	blup	24	0.01	1.0e-02	-4.9	5.2	2.1e-07	-0.75	0.00	0.84	FALSE
25	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	EML3	0.04	0.05	blup	27	0.05	3.5e-06	-5.2	-5.2	2.5e-07	0.92	0.01	0.98	FALSE
26	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	EEF1G	0.08	0.00	blup	27	0.04	1.3e-02	-4.9	5.2	2.2e-07	-0.89	0.02	0.80	FALSE
27	The Cancer Genome Atlas	Prostate Adenocarcinoma	EML3	0.09	0.14	lasso	1	0.14	3.4e-14	-5.2	-5.2	1.5e-07	1.00	0.01	0.99	FALSE
28	The Cancer Genome Atlas	Soft Tissue Sarcoma	ROM1	0.06	0.05	blup	24	0.03	8.1e-03	-4.9	5.1	3.1e-07	-0.96	0.01	0.84	FALSE
29	The Cancer Genome Atlas	Stomach Adenocarcinoma	EEF1G	0.05	0.07	blup	27	0.07	1.7e-05	-4.9	5.2	2.4e-07	-0.95	0.02	0.97	FALSE
30	The Cancer Genome Atlas	Stomach Adenocarcinoma	ROM1	0.05	0.08	lasso	3	0.08	3.1e-06	-5.2	5.3	1.3e-07	-0.94	0.01	0.99	FALSE
31	The Cancer Genome Atlas	Thyroid Carcinoma	EML3	0.11	0.10	blup	28	0.12	2.3e-11	-5.2	-5.3	1.4e-07	0.92	0.02	0.98	FALSE