Best TWAS P=8.52e-09 · Best GWAS P=2.22e-07 conditioned to 0.0806
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | RP1-283E3.4 | 0.65 | 0.14 | lasso | 9 | 0.33 | 5.1e-28 | -3.3 | -5.2 | 2.2e-07 | 0.00 | 0.03 | 0.21 | FALSE |
| 2 | GTEx | Cells Transformed fibroblasts | RP1-283E3.4 | 0.59 | 0.13 | lasso | 8 | 0.29 | 3.0e-22 | 2.4 | -5.2 | 2.2e-07 | 0.01 | 0.04 | 0.02 | FALSE |
| 3 | GTEx | Esophagus Mucosa | RP1-283E3.4 | 0.53 | 0.12 | enet | 20 | 0.22 | 4.1e-15 | -3.3 | -5.4 | 8.2e-08 | 0.02 | 0.03 | 0.21 | FALSE |
| 4 | GTEx | Esophagus Muscularis | RP1-283E3.4 | 0.46 | 0.14 | enet | 23 | 0.24 | 1.6e-14 | -3.3 | -5.8 | 8.5e-09 | 0.01 | 0.03 | 0.20 | TRUE |
| 5 | GTEx | Esophagus Muscularis | RP3-395M20.12 | 0.08 | 0.06 | enet | 6 | 0.06 | 2.3e-04 | 4.4 | -5.2 | 2.6e-07 | 0.78 | 0.02 | 0.95 | TRUE |
| 6 | GTEx | Thyroid | RP1-283E3.4 | 0.59 | 0.04 | lasso | 10 | 0.22 | 3.8e-17 | -3.3 | -5.5 | 3.3e-08 | 0.00 | 0.03 | 0.16 | FALSE |