Best TWAS P=3.95e-09 · Best GWAS P=2.71e-09 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Skin Sun Exposed Lower leg | TEX10 | 0.27 | 0.27 | lasso | 8 | 0.28 | 7.0e-23 | 5.8 | 5.7 | 1.2e-08 | 0.77 | 0.02 | 0.98 | FALSE |
2 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | INVS | 0.09 | 0.02 | enet | 11 | 0.04 | 4.0e-05 | 3.9 | 5.1 | 3.0e-07 | 0.71 | 0.04 | 0.67 | FALSE |
3 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | INVS | 0.16 | 0.12 | enet | 8 | 0.08 | 2.8e-04 | 5.6 | 5.9 | 3.9e-09 | 0.99 | 0.01 | 0.98 | TRUE |