Best TWAS P=3.02e-16 · Best GWAS P=1.36e-18 conditioned to 0.00595
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | LOC100499489 | 0.06 | 0.00 | bslmm | 297 | 0.02 | 1.2e-03 | 1.2 | -5.4 | 7.8e-08 | -0.49 | 0.02 | 0.77 | FALSE |
| 2 | CommonMind | Brain Pre-frontal Cortex | NEBL | 0.07 | 0.01 | blup | 662 | 0.03 | 9.7e-05 | -4.2 | -5.5 | 3.1e-08 | -0.03 | 0.76 | 0.01 | TRUE |
| 3 | GTEx | Artery Tibial | CASC10 | 0.05 | 0.06 | lasso | 4 | 0.02 | 1.3e-02 | 3.3 | 5.3 | 1.3e-07 | 0.52 | 0.27 | 0.44 | FALSE |
| 4 | GTEx | Skin Sun Exposed Lower leg | MLLT10 | 0.06 | 0.02 | lasso | 4 | 0.03 | 8.0e-04 | 8.2 | -8.2 | 3.0e-16 | -0.94 | 0.01 | 0.99 | TRUE |
| 5 | GTEx | Skin Sun Exposed Lower leg | CASC10 | 0.08 | 0.02 | lasso | 5 | 0.01 | 6.1e-02 | 6.2 | 7.3 | 2.7e-13 | 0.90 | 0.10 | 0.79 | FALSE |
| 6 | GTEx | Spleen | MLLT10 | 0.16 | 0.02 | lasso | 7 | 0.02 | 1.0e-01 | 6.2 | -7.4 | 1.2e-13 | -0.92 | 0.02 | 0.64 | FALSE |