Best TWAS P=9.68e-10 · Best GWAS P=4.41e-09 conditioned to 0.236
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | PLEKHA1 | 0.14 | 0.06 | lasso | 2 | 0.03 | 2.4e-03 | 5.8 | -5.9 | 3.8e-09 | -0.99 | 0.01 | 0.99 | FALSE |
| 2 | GTEx | Nerve Tibial | PLEKHA1 | 0.22 | 0.23 | enet | 17 | 0.19 | 1.1e-13 | 5.8 | -5.8 | 5.4e-09 | -0.97 | 0.01 | 0.99 | FALSE |
| 3 | METSIM | Adipose | PLEKHA1 | 0.05 | 0.03 | lasso | 4 | 0.04 | 3.6e-07 | 5.9 | -6.1 | 9.7e-10 | -0.86 | 0.01 | 0.99 | TRUE |
| 4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | PLEKHA1 | 0.04 | 0.05 | lasso | 2 | 0.04 | 4.3e-05 | 5.8 | -5.8 | 6.8e-09 | -0.99 | 0.01 | 0.99 | FALSE |
| 5 | The Cancer Genome Atlas | Thyroid Carcinoma | PLEKHA1 | 0.08 | 0.10 | lasso | 1 | 0.09 | 3.5e-09 | 5.8 | -5.8 | 5.3e-09 | -0.99 | 0.01 | 0.99 | FALSE |