TWAS hub - PLEKHA1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.06600	0.0230	4.7e-04	0.024	0.038	0.056	0.039	0.030	6.2e-04	2.0e-05	2.0e-07	1.6e-05	1.2e-04
2	GTEx	Adipose Subcutaneous	0.13500	0.0420	3.5e-04	0.061	NA	0.007	NA	0.028	9.5e-06	NA	7.6e-02	NA	2.4e-03
3	GTEx	Artery Tibial	0.16410	0.0462	6.5e-05	0.059	NA	0.077	NA	0.012	2.0e-05	NA	1.3e-06	NA	3.6e-02
4	GTEx	Breast Mammary Tissue	0.29700	0.0850	1.7e-03	0.051	NA	0.011	NA	0.003	1.2e-03	NA	8.6e-02	NA	2.3e-01
5	GTEx	Breast Mammary Tissue (Male)	0.00124	0.0812	5.0e-01	0.023	NA	-0.013	NA	0.025	9.6e-02	NA	9.5e-01	NA	8.6e-02
6	GTEx	Muscle Skeletal	0.10130	0.0344	1.2e-03	0.040	NA	0.016	NA	0.040	8.6e-05	NA	9.4e-03	NA	8.2e-05
7	GTEx	Nerve Tibial	0.22340	0.0469	1.9e-08	0.227	NA	0.193	NA	0.016	4.4e-16	NA	1.1e-13	NA	2.6e-02
8	GTEx	Pancreas	0.29400	0.0770	3.7e-04	0.045	NA	0.004	NA	0.074	5.4e-03	NA	2.2e-01	NA	4.7e-04
9	GTEx	Skin Sun Exposed Lower leg	0.16000	0.0540	4.9e-04	0.018	NA	0.004	NA	0.011	1.1e-02	NA	1.4e-01	NA	4.0e-02
10	METSIM	Adipose	0.04740	0.0170	1.3e-03	0.033	0.025	0.042	0.032	0.044	9.3e-06	8.6e-05	5.6e-07	1.2e-05	3.6e-07
11	NTR	Blood	0.05130	0.0127	5.4e-09	0.047	0.027	0.038	0.040	0.045	5.4e-15	3.4e-09	3.0e-12	4.8e-13	2.5e-14
12	ROSMAP	Brain Pre-frontal Cortex	0.05610	0.0208	2.9e-03	0.053	0.011	0.039	0.026	0.046	2.2e-07	1.1e-02	9.0e-06	2.4e-04	1.3e-06
13	TCGA	Brain Lower Grade Glioma	0.04180	0.0214	9.4e-04	0.047	0.022	0.031	NA	0.037	4.1e-06	1.2e-03	1.7e-04	NA	4.3e-05
14	TCGA	Pheochromocytoma and Paraganglioma	0.08400	0.0450	6.9e-03	0.063	0.024	0.010	NA	0.018	1.7e-03	4.0e-02	1.2e-01	NA	6.0e-02
15	TCGA	Rectum Adenocarcinoma	0.45400	0.1170	6.7e-03	-0.012	0.073	0.040	NA	-0.011	8.6e-01	8.7e-03	4.1e-02	NA	7.3e-01
16	TCGA	Thyroid Carcinoma	0.07800	0.0330	2.1e-06	0.099	0.061	0.067	NA	0.091	7.0e-10	1.3e-06	4.2e-07	NA	3.5e-09

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	6	7	8	9	10	12	13	14	15	16
Hypothyroidism (self reported)	13.3	30.5	56.0	6.1	-6.8	-5.0	-4.5	-6.2	-5.9	-3.4	-5.8	-6.6	-7.5	-6.8	-6.9	1.4	-6.8
Hypothyroidism/myxoedema (self-reported)	9.6	18.7	34.8	4.1	-5.3	-3.9	-3.5	-5.0	-4.5	-2.7	-4.8	-5.5	-5.9	-5.3	-5.3	1.1	-5.3
Type 2 Diabetes (T2D) (2012)	8.7	10.0	21.5	-1.5	4.6	3.5	2.4	2.9	4.5	2.0	2.8	3.8	2.5	4.6	4.5	-0.3	4.2
Birth weight	7.8	16.9	37.2	2.5	-5.8	-3.9	-1.1	-3.6	-6.1	-2.9	-3.6	-5.2	-3.9	-5.9	-5.6	-0.0	-5.9
Fractured/broken bones in last 5 years	7.2	9.3	20.0	2.0	-4.3	-2.2	-2.3	-2.5	-3.9	-1.9	-2.9	-3.9	-3.2	-4.3	-4.5	0.9	-4.3
Medication: Levothyroxine sodium	6.7	11.3	20.6	3.0	-4.5	-3.3	-2.5	-3.3	-4.0	-1.7	-2.8	-3.8	-4.3	-4.5	-4.3	2.1	-4.5
Alzheimer’s Disease (including proxy)	6.6	9.6	22.9	-1.6	4.5	2.9	0.9	2.5	4.8	2.3	2.5	4.0	2.5	4.6	4.2	-0.6	4.5
Height	6.2	120.0	237.2	7.6	-13.6	-8.9	-7.7	-12.5	-12.4	-9.2	-14.2	-15.4	-13.6	-13.5	-12.3	-0.6	-13.6
Basal metabolic rate	5.4	30.0	59.2	3.8	-7.1	-4.3	-4.8	-5.8	-6.4	-3.6	-6.7	-7.7	-7.0	-6.9	-6.1	0.3	-6.9
Leg fat-free mass (left)	5.3	28.3	58.2	3.5	-6.8	-4.3	-4.8	-5.8	-6.3	-3.8	-6.6	-7.6	-6.5	-6.6	-5.8	-0.4	-6.6
Leg predicted mass (left)	5.3	28.1	57.2	3.5	-6.8	-4.3	-4.8	-5.8	-6.2	-3.7	-6.5	-7.6	-6.5	-6.6	-5.8	-0.3	-6.6
Standing height	5.3	53.0	108.2	4.3	-8.8	-4.9	-5.5	-8.9	-7.5	-6.8	-10.2	-10.4	-9.5	-8.6	-8.1	-1.0	-8.6
Leg fat-free mass (right)	5.3	28.1	57.0	3.6	-6.7	-4.3	-4.8	-5.9	-6.1	-4.0	-6.7	-7.5	-6.6	-6.5	-5.8	-0.4	-6.5
Whole body water mass	5.3	30.3	59.1	4.0	-7.1	-4.3	-4.8	-6.0	-6.3	-3.6	-6.8	-7.7	-7.2	-6.9	-6.0	0.3	-6.9
Eye problems/disorders: Diabetes related eye disease	5.2	5.7	10.8	-1.1	3.0	3.3	2.0	2.4	3.0	1.4	2.5	2.9	2.7	3.0	3.1	-0.1	3.0
Whole body fat-free mass	5.2	29.6	58.8	3.9	-7.0	-4.1	-4.8	-6.0	-6.2	-3.6	-6.8	-7.7	-7.1	-6.8	-5.9	0.2	-6.8
Leg predicted mass (right)	5.2	27.9	56.0	3.7	-6.6	-4.3	-4.8	-5.9	-6.1	-3.9	-6.6	-7.5	-6.6	-6.5	-5.7	-0.4	-6.5
Weight	5.1	25.1	49.9	2.9	-6.6	-4.3	-4.4	-5.2	-6.2	-3.3	-5.8	-7.1	-6.0	-6.5	-5.7	0.6	-6.5
Arm predicted mass (right)	5.1	26.1	47.2	4.5	-6.5	-4.0	-4.4	-5.6	-5.7	-3.5	-6.0	-6.8	-6.9	-6.4	-5.7	0.5	-6.3
Diabetes (mother)	5.0	6.3	12.0	-0.5	3.4	2.7	1.3	2.5	3.3	2.6	2.9	3.5	2.2	3.3	3.3	1.0	3.2
Number of incorrect matches in round	5.0	8.4	18.7	-1.5	3.9	4.3	2.0	2.8	4.1	1.7	2.5	3.6	2.6	3.9	3.1	-0.8	3.8
Arm fat-free mass (left)	5.0	25.1	47.2	3.8	-6.5	-4.0	-4.0	-5.3	-5.8	-3.2	-6.0	-6.9	-6.7	-6.4	-5.5	1.2	-6.4
Arm fat-free mass (right)	4.9	25.0	48.3	4.4	-6.2	-3.8	-4.3	-5.7	-5.4	-3.5	-6.2	-6.7	-6.9	-6.1	-5.5	0.3	-6.1
Trunk fat-free mass	4.8	27.4	54.3	3.8	-6.7	-3.7	-4.5	-5.7	-5.9	-3.1	-6.7	-7.4	-7.1	-6.6	-5.7	0.3	-6.5
Trunk predicted mass	4.8	27.3	54.0	3.8	-6.7	-3.7	-4.5	-5.7	-5.9	-3.2	-6.7	-7.3	-7.1	-6.6	-5.7	0.3	-6.6
Comparative height size at age 10	4.8	26.3	51.6	4.3	-6.9	-2.9	-4.9	-4.8	-5.9	-2.5	-5.9	-6.8	-7.2	-6.8	-6.1	0.1	-6.7
Birth weight of first child	4.7	8.5	17.5	1.7	-4.0	-2.9	-0.3	-2.7	-4.2	-0.9	-2.7	-3.8	-3.0	-4.1	-4.2	-1.7	-4.0
Alzheimer’s Disease (in mother)	4.6	5.4	11.8	-2.3	3.2	1.6	0.9	1.7	3.4	1.2	1.9	3.0	2.3	3.4	3.1	-0.9	3.4
Prospective memory result	4.6	5.7	10.6	-2.6	3.1	1.9	2.8	1.7	3.3	1.0	1.9	3.1	2.4	3.2	3.0	0.3	3.2
Trunk fat mass	4.5	19.1	37.3	2.2	-5.9	-4.2	-4.2	-4.2	-5.8	-2.7	-4.5	-6.1	-4.7	-5.8	-5.0	0.6	-5.8
Arm predicted mass (left)	4.4	22.5	41.9	3.7	-6.2	-3.7	-3.6	-5.0	-5.5	-2.9	-5.7	-6.5	-6.4	-6.1	-5.2	1.0	-6.1
Lung FEV1/FVC ratio	4.0	20.3	37.6	-4.6	4.0	4.9	4.8	5.2	3.5	3.8	5.9	5.2	6.1	3.7	4.8	6.1	3.8
Hair/balding pattern: Pattern 3	3.8	5.6	12.2	-2.3	2.0	2.2	3.1	2.7	2.0	1.8	3.5	3.1	2.7	2.0	2.2	3.2	1.9
Hip circumference	3.7	15.8	33.2	1.5	-5.2	-3.6	-3.5	-4.0	-5.2	-2.7	-4.4	-5.8	-4.4	-5.1	-4.8	-0.1	-5.1
Back pain experienced in last month	3.6	5.3	18.4	2.6	-2.8	-0.4	-3.5	-0.3	-2.3	1.9	-0.3	-1.5	-3.0	-2.8	-2.1	4.3	-2.8
Medication: Gliclazide	3.6	4.0	11.5	-1.6	3.0	1.4	0.5	1.2	3.1	1.0	1.1	2.3	1.6	3.0	3.4	-0.6	3.0
Intelligence (Savage-Jansen 2018)	3.5	10.8	23.5	2.1	-4.6	-3.8	-1.8	-2.9	-4.8	-1.6	-2.9	-4.1	-3.2	-4.6	-4.1	-0.8	-4.5
Rheumatoid Arthritis	3.5	4.8	11.2	0.5	-3.2	-3.0	-0.5	-1.7	-3.3	-1.4	-1.6	-2.9	-1.7	-3.1	-2.6	0.9	-3.2
Waist circumference	3.4	12.3	24.4	1.6	-4.8	-4.0	-3.7	-2.9	-4.9	-1.8	-3.1	-4.7	-3.4	-4.7	-4.0	1.1	-4.8
Lung cancer (father)	3.4	4.0	8.2	-1.0	2.9	1.5	0.1	1.9	2.7	1.2	1.9	2.6	2.5	2.9	2.4	-1.1	2.8
Medication: Seretide 50 evohaler	3.4	3.9	8.2	-0.2	-2.3	-2.2	-1.1	-2.6	-2.2	-2.4	-2.6	-2.9	-1.8	-2.3	-2.2	0.1	-2.3
Friendships satisfaction	3.4	4.2	10.4	-1.4	2.4	2.0	3.2	2.1	2.1	1.0	1.7	2.5	2.4	2.4	2.5	-1.0	2.5
Illnesses of siblings	3.3	4.6	8.8	1.8	-2.6	-1.2	-2.7	-2.1	-2.3	-2.2	-2.7	-3.0	-2.1	-2.6	-2.3	1.2	-2.5
Medication for cholesterol	3.3	5.0	9.8	1.2	-3.1	-2.1	-0.8	-2.4	-2.9	-1.8	-2.2	-2.9	-2.4	-3.1	-2.8	0.0	-3.1
Whole body fat mass	3.2	13.2	25.0	2.0	-4.9	-3.6	-3.2	-3.4	-5.0	-2.1	-3.6	-5.0	-3.9	-4.9	-4.2	0.7	-4.9
Relative age of first facial hair	3.1	6.5	12.6	1.6	-2.7	-3.3	-0.5	-3.5	-2.6	-3.5	-2.9	-3.1	-2.7	-2.7	-3.3	0.1	-2.8
Taking other prescription medications	3.1	4.8	10.8	1.9	-2.5	-3.3	-2.2	-2.1	-2.6	-1.5	-2.3	-2.7	-2.5	-2.5	-2.2	-1.1	-2.5
Forced vital capacity (FVC)	3.1	12.1	35.8	1.8	-3.6	-0.2	-4.5	-3.5	-2.8	-2.8	-6.0	-5.5	-4.6	-3.5	-3.1	-2.8	-3.5
High blood pressure (siblings)	3.1	4.5	8.8	-2.0	3.0	1.1	2.0	1.5	2.8	1.1	1.8	2.6	2.0	3.0	2.4	-2.3	2.9
Arm fat mass (left)	3.1	12.7	24.7	1.8	-4.9	-3.6	-3.2	-3.3	-5.0	-1.9	-3.5	-4.9	-3.7	-4.8	-4.1	0.5	-4.8
Respiratory disease	3.0	6.7	12.7	2.2	-2.8	-3.6	-2.2	-3.3	-2.3	-2.8	-2.6	-2.6	-3.5	-2.7	-3.5	0.2	-2.8
Arm fat mass (right)	3.0	12.5	24.9	1.7	-4.8	-3.5	-2.8	-3.3	-4.9	-2.0	-3.6	-5.0	-3.7	-4.8	-4.1	0.5	-4.8
Verbal and Numeric Reasoning (VNR)	2.8	6.7	12.8	1.6	-3.4	-3.3	-1.0	-2.6	-3.6	-1.8	-2.7	-3.3	-2.6	-3.4	-3.2	-0.9	-3.4
Asthma	2.8	5.6	10.9	2.2	-2.7	-3.1	-2.2	-2.7	-2.5	-1.9	-2.3	-2.5	-2.9	-2.6	-3.3	-0.4	-2.7
Forced vital capacity (FVC), Best measure	2.8	10.1	32.4	1.7	-3.1	-0.2	-3.5	-3.5	-2.4	-2.7	-5.7	-5.0	-4.1	-3.0	-3.0	-3.4	-2.9
Exposure to tobacco smoke outside home	2.8	3.7	6.4	-1.9	2.5	1.1	2.0	1.8	2.1	1.6	1.5	2.1	2.5	2.4	1.9	-2.4	2.4
Illnesses of siblings: Diabetes	2.8	3.5	11.3	0.1	1.8	2.3	0.4	2.6	1.6	3.4	2.7	2.5	1.4	1.7	2.0	0.3	1.7
Trunk fat percentage	2.7	10.9	22.7	1.2	-4.6	-3.6	-3.4	-2.8	-4.8	-2.0	-2.8	-4.5	-3.0	-4.5	-3.9	0.7	-4.5
Pulse wave Arterial Stiffness index	2.7	3.1	7.3	1.7	-2.4	-2.6	-1.6	-1.1	-2.7	-0.5	-0.9	-1.8	-1.1	-2.3	-2.3	-1.2	-2.3
Time employed in main current job	2.6	3.0	5.6	1.0	-2.1	-2.1	-0.9	-2.3	-1.9	-1.8	-2.1	-2.3	-1.4	-2.0	-2.4	0.3	-2.0
Asthma (self-reported)	2.6	5.2	10.8	1.9	-2.7	-2.9	-2.1	-2.6	-2.4	-1.8	-2.2	-2.4	-2.9	-2.6	-3.3	-0.6	-2.6
Diabetes (father)	2.5	3.1	5.7	-1.2	2.0	1.1	2.1	2.1	1.9	1.0	2.3	2.3	2.2	2.1	2.4	-0.2	2.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	2.5	2.9	6.2	0.7	-2.3	-1.5	-2.4	-1.1	-2.0	-0.8	-1.7	-2.5	-1.9	-2.2	-1.6	1.5	-2.2
Illnesses of father: High blood pressure	2.5	3.1	7.5	-0.7	2.5	2.7	0.8	1.3	2.7	0.6	0.7	1.9	1.4	2.5	2.5	-1.3	2.5
Knee pain experienced in last month	2.3	3.5	6.3	2.5	-2.2	-2.4	-1.1	-2.2	-1.8	-1.5	-1.9	-2.0	-2.5	-2.0	-2.2	0.1	-2.1
Crohns Disease (2012)	2.2	3.5	9.4	1.6	2.4	3.1	1.8	1.2	2.9	1.2	1.3	2.3	0.5	2.5	1.8	-0.4	2.6
Fasting Glucose	2.2	2.6	8.2	2.1	-1.7	-1.5	-2.9	-1.6	-1.3	-0.6	-1.4	-1.2	-2.4	-1.6	-2.2	-0.4	-1.7
Myopia	2.2	3.2	6.8	2.1	-1.8	-2.6	-1.5	-2.6	-1.9	-1.6	-1.8	-1.4	-2.2	-1.8	-2.2	-0.8	-1.7
Systolic Blood Pressure	2.1	10.4	30.5	-1.0	4.7	4.9	1.2	1.7	5.5	2.6	0.6	2.9	0.5	4.7	4.0	-2.9	4.7
Allergy	2.1	4.7	8.2	-2.1	2.7	2.7	1.8	2.4	2.5	1.9	2.0	2.4	2.2	2.7	2.9	-0.4	2.7
Medication: Blood pressure	2.1	4.0	8.9	-1.3	3.0	2.3	0.0	1.7	2.9	1.3	1.4	2.2	1.5	3.0	2.6	-1.7	2.9
Hand grip strength (right)	2.0	5.5	14.2	2.2	-2.6	0.9	-2.5	-2.4	-1.3	-1.4	-3.3	-3.1	-3.8	-2.6	-2.7	2.3	-2.5
Tense / ‘highly strung’	2.0	3.4	6.6	-1.8	2.6	1.7	1.8	1.3	2.5	0.5	1.4	2.0	2.0	2.5	2.6	0.7	2.5
Wheeze or whistling in the chest in last year	2.0	3.6	9.7	1.2	-2.7	-3.1	-1.8	-1.3	-2.9	-0.8	-0.8	-1.8	-1.4	-2.6	-2.3	0.8	-2.6
Number of full sisters	2.0	2.4	10.2	0.3	1.0	1.8	-0.5	2.1	1.0	3.2	2.5	2.1	0.9	0.9	1.3	1.7	1.0
Schizophrenia (2014)	1.9	4.2	8.4	-2.2	2.8	1.5	0.4	1.9	2.7	1.3	1.6	2.2	2.7	2.9	2.9	-1.0	2.8
Blood clot in the leg (DVT)	1.9	2.4	5.1	2.2	-2.2	-0.8	-1.0	-1.1	-2.2	0.1	-1.2	-1.8	-1.5	-2.2	-2.1	-0.2	-2.3
Worry (Nagel 2018)	1.8	3.7	8.0	0.4	2.8	2.4	2.3	1.5	2.8	1.1	1.3	2.4	1.4	2.7	2.3	-0.4	2.8
Hair/balding pattern: Pattern 2	1.8	2.3	5.8	2.4	-1.5	-1.1	-2.1	-1.2	-1.5	-0.6	-1.5	-1.5	-1.8	-1.6	-1.7	-1.8	-1.6
Serious illness, injury or assault of a close relative in last 2 years	1.8	2.0	4.4	-1.6	1.5	1.7	-0.0	2.1	1.3	2.1	1.4	1.3	2.0	1.4	1.6	0.1	1.4
Mother’s age at death	1.8	2.2	5.7	-0.5	1.8	2.4	2.1	1.3	1.9	1.7	1.2	1.5	1.3	1.7	1.3	0.1	1.7
Crohns Disease (2017)	1.7	3.8	7.9	-0.0	2.6	2.8	2.3	1.6	2.8	1.4	1.6	2.3	1.2	2.6	2.0	-1.4	2.6
Major Depression (MDD)	1.7	2.0	5.0	-1.0	1.9	1.7	-0.6	1.1	2.2	0.6	0.5	1.5	1.4	2.1	2.0	-1.1	2.0
Lung FVC	1.7	8.5	24.2	3.5	-3.0	-0.0	-4.9	-1.7	-2.6	0.1	-4.0	-4.0	-4.0	-3.0	-3.0	-2.3	-3.0
Medication: Ramipril	1.7	2.2	5.0	-0.9	1.8	1.6	0.7	1.7	1.9	2.0	1.5	1.6	1.2	1.7	2.2	0.8	1.7
Happiness	1.7	2.0	4.2	1.8	-2.0	-1.1	0.9	-1.3	-2.0	-0.3	-1.3	-1.5	-1.7	-2.0	-1.5	0.3	-2.0
Seen a psychiatrist for nerves, anxiety, tension or depression	1.7	2.2	5.2	-1.6	1.9	1.5	2.3	1.0	2.1	0.1	1.0	1.7	1.4	1.9	1.5	1.0	1.9
Pulse wave peak to peak time	1.7	2.0	6.1	-1.4	1.9	2.5	1.3	0.5	2.3	0.2	0.2	1.1	0.5	1.8	1.7	1.1	1.8
Deep venous thrombosis (DVT) (self-reported)	1.7	2.2	5.3	2.3	-2.1	-0.6	-1.0	-0.8	-2.2	0.4	-0.8	-1.6	-1.3	-2.1	-1.9	-0.1	-2.2
Leg fat mass (left)	1.7	6.7	13.2	1.4	-3.5	-2.5	-1.9	-2.4	-3.6	-1.4	-2.5	-3.6	-2.8	-3.5	-3.0	0.7	-3.5
Irritable Bowel Disease (IBD)	1.6	3.9	9.0	0.3	2.7	1.9	2.8	1.0	3.0	0.8	1.4	2.5	0.8	2.7	1.8	-2.5	2.8
Sitting height	1.6	11.3	40.6	1.2	-2.9	-0.4	-2.7	-5.1	-1.7	-3.8	-6.4	-5.1	-5.2	-2.8	-2.7	-1.9	-2.8
Fluid intelligence score	1.6	3.3	8.1	2.2	-2.5	-1.2	-0.7	-1.4	-2.5	-0.4	-1.5	-2.1	-2.1	-2.5	-2.8	-0.3	-2.5
Illnesses of mother	1.6	2.0	5.9	0.9	-2.2	-1.9	-1.0	-0.3	-2.4	0.4	-0.2	-1.5	-0.8	-2.2	-1.9	0.1	-2.2
Breastfed as a baby	1.6	2.0	7.6	0.4	-1.8	-1.9	-2.8	-1.0	-1.8	-0.6	-0.3	-1.1	-0.8	-1.8	-1.7	1.1	-1.8
Leg fat mass (right)	1.6	6.1	12.6	1.3	-3.4	-2.3	-1.8	-2.2	-3.5	-1.1	-2.4	-3.5	-2.6	-3.4	-2.9	0.8	-3.4
Medication: Paracetamol	1.6	2.5	6.8	1.0	-2.0	-1.6	-0.3	-1.5	-2.1	-1.0	-2.1	-2.6	-1.3	-2.0	-1.9	-1.1	-2.0
HDL Cholesterol	1.5	2.5	5.3	0.7	-2.3	-1.5	-1.5	-1.2	-2.2	-0.6	-0.9	-1.7	-1.5	-2.3	-2.3	0.9	-2.3
Bilateral oophorectomy (both ovaries removed)	1.5	1.8	4.2	2.0	-1.5	-1.4	-0.7	-1.4	-1.2	-0.5	-1.5	-1.6	-1.8	-1.4	-1.3	1.4	-1.5
Gout (self-reported)	1.5	2.0	6.1	-2.5	1.2	1.6	-1.2	2.0	0.9	2.3	1.2	0.9	1.6	1.1	1.7	-0.6	1.1
Body fat percentage	1.5	5.8	13.9	0.9	-3.4	-2.6	-2.5	-1.7	-3.7	-1.1	-1.6	-3.2	-2.0	-3.4	-2.8	1.0	-3.4
Forced expiratory volume in 1-second (FEV1), predicted	1.5	3.2	9.0	1.6	-1.4	0.0	-2.6	-2.6	-0.9	-2.1	-3.0	-2.2	-2.6	-1.4	-1.3	-1.1	-1.3
Arm fat percentage (left)	1.5	5.9	15.5	0.9	-3.5	-2.8	-2.6	-1.6	-3.9	-0.8	-1.6	-3.2	-1.8	-3.5	-2.8	0.4	-3.5
Diabetes diagnosed by doctor	1.5	2.4	5.5	0.7	1.9	0.8	1.7	1.4	1.6	1.9	1.8	2.3	1.4	1.9	2.2	0.1	1.9
Commuting to job workplace: Public transport	1.5	1.7	6.4	0.1	-1.0	-1.2	0.1	-2.5	-0.8	-1.9	-2.2	-1.7	-1.9	-1.0	-1.1	-0.6	-1.0
Cardiovascular Disease	1.4	4.5	14.3	-0.6	2.9	3.8	1.1	1.4	3.5	0.4	0.8	2.1	0.6	3.0	2.6	-1.7	3.0
Hearing difficulty/problems: Yes	1.4	2.1	11.9	1.0	-1.7	-0.9	-2.4	-0.1	-1.6	0.5	-0.1	-0.9	-0.9	-1.7	-0.9	3.4	-1.7
Shortness of breath walking on level ground	1.4	1.6	4.2	0.5	-1.9	-1.0	-1.1	0.1	-2.0	0.7	0.1	-1.0	-0.8	-2.0	-1.3	2.0	-2.0
Migraine (self-reported)	1.4	1.7	4.9	1.3	-1.2	-0.3	-1.6	-1.2	-1.3	-0.2	-2.2	-2.2	-1.4	-1.3	-1.5	-1.3	-1.2
Number of self-reported non-cancer illnesses	1.4	2.5	7.9	1.3	-1.5	-1.2	-1.7	-1.9	-1.2	-0.9	-2.6	-2.3	-2.8	-1.5	-1.1	-0.2	-1.5
Bipolar Disorder or Schizophrenia	1.3	3.1	7.6	-1.5	2.5	1.1	0.9	1.3	2.4	1.1	1.0	1.8	2.2	2.6	2.8	-1.3	2.4
Coronary Artery Disease (CAD)	1.3	1.6	5.8	-0.5	1.8	1.1	1.8	0.4	2.4	0.3	0.5	1.6	0.4	1.8	1.5	1.6	0.6
Type 2 Diabetes (T2D) (2018)	1.3	2.4	5.2	0.9	2.0	1.4	1.0	1.4	1.8	1.8	1.5	2.3	1.1	2.0	2.3	-0.8	2.0
Impedance of leg (right)	1.3	6.3	12.3	-1.7	3.0	2.4	2.8	2.8	2.9	1.4	3.1	3.5	3.2	2.9	2.4	1.3	3.0
Impedance of leg (left)	1.3	6.1	13.0	-1.6	3.0	2.3	2.7	2.6	3.1	1.0	3.1	3.6	3.0	3.0	2.3	1.1	3.0
Diabetes (self-reported)	1.3	1.9	4.4	1.2	1.7	0.7	1.1	1.4	1.4	2.1	1.5	2.1	1.0	1.7	1.9	-0.3	1.7
Eye problems/disorders: Cataract	1.3	1.5	4.0	-0.3	-1.7	-1.1	0.5	-0.9	-2.0	-1.0	-1.0	-1.6	-1.0	-1.8	-1.1	-1.1	-1.9
Osteoporosis (self-reported)	1.3	1.7	7.7	2.8	-1.1	-1.6	1.1	-1.6	-0.9	-1.6	-0.5	-0.1	-1.9	-1.1	-1.1	0.6	-1.1
Illnesses of father: None of the above (group 1)	1.3	1.6	4.6	0.3	-1.8	-2.0	-0.5	-0.6	-2.1	0.1	-0.8	-1.6	-0.6	-1.8	-1.6	0.2	-1.8
Stomach or abdominal pain in last month	1.2	1.5	3.2	-1.8	1.5	1.6	1.7	1.0	1.4	0.7	0.2	0.7	1.1	1.5	1.6	-1.0	1.5
Nervous feelings	1.2	2.2	11.9	0.3	1.7	1.2	3.4	1.1	1.5	1.2	1.6	1.8	1.1	1.5	1.2	0.6	1.5
Frequency of tenseness / restlessness in last 2 weeks	1.2	1.8	3.2	-0.1	1.7	1.4	1.2	1.6	1.5	1.3	1.4	1.6	1.4	1.6	1.8	-1.0	1.6
Heart attack	1.2	1.5	4.6	0.1	1.3	0.4	0.5	1.3	1.3	1.4	1.9	2.1	0.7	1.2	1.3	1.7	1.3
Arm fat percentage (right)	1.2	4.9	13.0	0.3	-3.2	-2.4	-2.0	-1.4	-3.6	-0.6	-1.6	-3.0	-1.6	-3.2	-2.6	0.5	-3.2
Forced expiratory volume in 1-second (FEV1)	1.2	4.1	13.6	0.9	-2.1	1.4	-3.2	-1.7	-1.4	-1.0	-3.7	-3.4	-2.5	-2.1	-1.6	-0.8	-1.9
Ever highly irritable/argumentative for 2 days	1.2	1.4	3.5	-0.8	0.7	1.5	1.3	1.7	0.5	1.9	1.9	1.6	1.3	0.6	1.0	1.1	0.6
Medication: Paracetamol	1.2	2.0	5.7	1.0	-1.8	-1.6	-0.7	-1.2	-2.0	-0.6	-1.8	-2.4	-1.2	-1.8	-1.6	-0.1	-1.8
Eye problems/disorders: None of the above	1.2	1.4	5.0	0.2	1.0	1.2	-2.2	0.6	1.7	0.5	0.8	1.3	0.6	1.2	0.7	2.2	1.2
Hypertension (Self-reported)	1.2	3.2	8.2	-1.0	2.7	2.5	1.5	1.0	2.9	0.4	0.6	1.6	0.8	2.7	2.5	-1.3	2.6
Medication: Atorvastatin	1.2	1.5	3.8	-0.2	1.4	1.9	1.4	1.1	1.6	1.2	1.1	1.6	0.5	1.3	1.3	1.3	1.3
Heart attack/myocardial infarction (self-reported)	1.2	1.5	4.6	-0.0	1.2	0.4	0.4	1.3	1.3	1.5	1.9	2.1	0.8	1.2	1.3	1.8	1.2
Bipolar Disorder (2018)	1.1	1.7	4.2	-0.7	1.7	0.6	1.1	1.1	1.7	0.6	1.2	1.5	1.8	1.8	2.1	-0.5	1.8
Number of treatments/medications taken	1.1	1.9	4.9	1.0	-1.4	-1.9	-0.7	-1.4	-1.4	-0.4	-2.2	-2.1	-1.9	-1.4	-1.0	-0.8	-1.5
Hayfever/allergic rhinitis (self-reported)	1.1	1.5	5.5	1.3	-1.6	-1.4	-2.3	0.1	-1.9	0.4	0.4	-0.4	-0.4	-1.6	-1.3	0.9	-1.6
Medication: Ventolin 100micrograms inhaler	1.1	1.4	4.1	0.2	-1.2	-1.4	-0.6	-1.1	-1.4	-1.4	-0.9	-1.0	-1.0	-1.2	-2.0	-1.6	-1.3
Angina (self-reported)	1.1	1.4	7.5	-0.0	0.3	-0.3	-0.3	2.0	0.1	1.6	2.7	2.0	1.4	0.2	0.6	1.5	0.3
Qualifications: nursing, teaching	1.1	1.8	6.5	-2.5	0.6	1.0	1.1	2.1	0.0	1.6	2.0	1.3	2.0	0.6	1.4	0.1	0.6
Osteoarthritis (self-reported)	1.1	1.5	4.9	-1.7	1.1	-0.7	1.3	1.6	0.3	0.4	1.7	1.4	2.2	1.0	1.6	-0.3	1.0
Basal cell carcinoma (self-reported)	1.1	1.3	2.7	-0.6	1.4	1.0	0.7	1.2	1.6	1.5	1.1	1.2	0.9	1.5	1.5	0.2	1.5
Neuroticism (2016)	1.0	1.4	3.9	-1.5	1.6	1.3	0.9	1.2	1.1	0.9	0.6	0.8	2.0	1.5	1.2	-0.7	1.7
Blood White Count	1.0	7.2	18.4	1.2	3.4	3.1	1.6	2.6	3.4	3.1	3.6	4.3	1.5	3.3	2.6	-0.2	3.3
Smoking Status	1.0	2.4	12.6	1.1	-1.9	-0.7	-3.5	-0.7	-1.9	-0.6	-0.9	-1.7	-1.4	-1.9	-1.2	1.3	-1.9
Angina	1.0	1.4	7.2	0.1	0.1	-0.3	-0.4	2.0	-0.1	1.5	2.7	1.8	1.3	0.0	0.4	1.7	0.1
Medication: Metformin	1.0	1.4	3.6	-0.2	1.4	0.9	0.5	1.2	1.1	1.9	1.4	1.8	1.0	1.3	1.6	0.6	1.3
High blood pressure	1.0	2.8	7.7	-0.8	2.6	2.1	0.8	0.8	2.8	-0.0	0.3	1.4	0.7	2.6	2.2	-1.8	2.6
Falls in the last year	1.0	1.3	7.4	-1.6	0.8	2.7	0.2	1.5	0.8	1.3	1.3	1.0	1.2	0.8	0.6	0.0	0.8
Medication: Ibuprofen (e.g. Nurofen)	1.0	1.3	5.8	-0.9	-1.0	-0.3	-1.2	-1.3	-0.8	-1.1	-2.4	-2.2	-0.7	-0.9	-0.3	0.4	-0.9
Medication: Lansoprazole	1.0	1.2	7.3	1.6	-0.9	0.1	-2.7	0.6	-0.5	1.0	0.1	-0.5	-0.9	-0.9	-0.2	2.0	-0.9
Headache pain in last month	1.0	1.7	8.2	-1.6	-0.6	1.3	-0.6	-0.5	-0.8	0.2	-2.9	-2.7	-0.3	-0.7	-0.5	-2.1	-0.6
Medication for pain relief, constipation, heartburn	1.0	1.8	5.6	0.2	1.9	1.2	1.0	0.7	2.2	-0.0	1.4	2.4	0.9	1.9	1.2	-0.4	1.9
Leg pain on walking	1.0	1.3	4.0	-2.0	0.4	-0.4	-0.4	1.8	-0.2	1.3	1.8	1.0	1.9	0.3	1.4	1.2	0.3
Illness, injury, bereavement, stress in last 2 years	1.0	1.2	4.4	1.2	-0.9	-1.1	-0.8	-1.5	-0.7	-2.1	-1.1	-0.7	-1.3	-0.8	-1.2	-1.5	-0.8
Heel T-Score	0.9	7.5	32.9	-5.7	3.3	2.4	-0.3	1.0	3.5	-1.1	-1.1	0.6	3.5	3.6	4.2	-0.2	3.5
Chronotype (morning person)	0.9	2.0	14.5	-1.4	1.3	1.7	3.8	1.0	1.0	0.2	0.9	1.0	1.7	1.1	0.1	-1.5	1.2
Chronic bronchitis/emphysema (father)	0.9	1.0	7.3	0.5	-0.9	-2.7	0.8	-0.8	-1.3	-0.8	-0.5	-0.6	-0.6	-0.9	-0.8	-1.0	-1.0
Body mass index (BMI)	0.9	3.9	9.1	0.9	-2.8	-2.2	-2.1	-1.4	-3.0	-0.4	-1.5	-2.6	-1.9	-2.7	-2.2	0.9	-2.8
Heel bone mineral density (BMD) T-score, automated (right)	0.9	2.0	6.4	-2.5	1.6	1.6	-1.2	0.9	2.1	0.2	-0.0	0.9	1.5	1.9	2.0	-0.4	1.9
Exposure to tobacco smoke at home	0.9	1.0	2.5	0.3	1.4	1.1	0.9	0.6	1.6	1.1	0.7	1.3	0.5	1.4	1.0	-0.0	1.4
Peak expiratory flow (PEF)	0.9	2.1	6.2	0.1	-2.1	0.8	-2.5	-0.3	-1.9	0.5	-0.9	-1.7	-1.1	-2.2	-1.6	1.4	-2.1
Mouth/teeth dental problems: Bleeding gums	0.9	1.2	2.7	0.4	1.5	1.5	-0.0	0.6	1.6	0.0	0.8	1.3	1.2	1.6	1.0	-0.8	1.6
Medication: Amlodipine	0.9	1.2	3.4	-0.3	1.5	0.9	-1.9	1.0	1.6	0.3	0.6	1.1	1.0	1.5	1.4	-0.7	1.4
Mood swings	0.9	1.6	5.8	-1.0	1.8	2.4	0.1	0.3	2.0	-0.2	-0.1	0.7	0.9	1.7	1.7	0.8	1.8
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.9	1.9	12.0	-0.7	1.5	3.5	0.3	1.7	1.4	1.0	0.6	0.9	1.4	1.4	1.4	-0.6	1.4
Age started oral contraceptive pill	0.9	1.2	4.3	-0.5	-1.2	-1.6	-0.1	-0.9	-1.2	-0.7	-1.2	-1.3	-0.8	-1.2	-0.5	2.1	-1.3
Vascular/heart problems diagnosed by doctor	0.9	2.6	6.8	0.7	-2.5	-1.8	-0.4	-1.0	-2.6	-0.1	-0.6	-1.5	-0.9	-2.5	-2.2	1.7	-2.5
Body Mass Index (BMI) (2010)	0.8	1.1	2.5	0.5	-1.1	-0.1	-1.5	-1.3	-0.8	-1.6	-1.4	-1.3	-1.1	-1.1	-1.1	0.3	-1.0
BMI	0.8	4.9	10.7	1.0	-3.2	-1.9	-2.6	-1.5	-3.3	-1.0	-1.7	-3.0	-1.9	-3.2	-2.6	0.5	-3.2
Hand grip strength (left)	0.8	2.2	7.8	1.5	-1.1	2.2	-2.2	-1.5	0.2	-0.1	-2.3	-1.6	-2.8	-1.0	-1.2	0.8	-0.9
Diverticular disease/diverticulitis (self-reported)	0.8	0.9	4.1	-1.5	0.5	0.6	-1.6	1.4	0.3	2.0	0.6	0.3	1.0	0.5	1.3	-0.1	0.6
High blood pressure (mother)	0.8	1.2	3.2	-1.1	1.6	1.7	0.3	0.3	1.8	-0.2	-0.3	0.5	0.3	1.6	1.4	-1.1	1.6
Pulse rate	0.8	1.4	5.1	-0.3	-1.7	-2.3	-0.6	-0.7	-1.9	0.4	-0.6	-1.4	-0.6	-1.6	-1.2	-0.1	-1.6
Forced expiratory volume in 1-second (FEV1), Best measure	0.8	2.4	9.3	0.5	-1.5	1.3	-2.4	-1.1	-1.0	-0.7	-3.1	-2.7	-1.6	-1.4	-1.2	-1.4	-1.3
Heart disease (mother)	0.8	0.9	3.7	1.0	-0.6	-0.2	0.2	-1.6	-0.0	-1.0	-1.5	-0.9	-1.9	-0.7	-0.9	1.3	-0.6
Commuting to job workplace: Car/motor vehicle	0.8	0.9	1.9	-0.1	1.3	-0.0	0.8	0.7	1.4	1.2	0.7	1.2	0.8	1.4	1.2	-1.0	1.4
Illnesses of father: Heart disease	0.8	1.1	6.6	-0.3	1.2	2.6	0.1	0.9	1.3	0.9	0.7	1.0	0.8	1.2	1.1	-0.4	1.2
Ever taken oral contraceptive pill	0.8	0.9	1.8	0.7	-1.1	-1.2	-0.2	-1.3	-0.7	-1.2	-1.1	-1.1	-0.9	-1.0	-0.9	0.8	-0.9
Alcohol drinker status: Never	0.8	0.9	6.7	2.6	0.8	-0.2	0.1	0.9	0.7	1.2	1.3	1.3	-0.0	0.7	0.3	0.5	0.7
Number of operations (self-reported)	0.8	1.2	2.8	0.4	-1.3	-1.3	-1.1	-1.2	-0.9	-0.9	-1.6	-1.7	-1.5	-1.2	-0.9	0.2	-1.3
Pain experienced in last month	0.8	1.3	3.6	0.2	1.4	0.5	1.3	0.7	1.4	-0.4	1.7	1.9	1.4	1.4	1.1	-0.7	1.4
Heart disease (siblings)	0.8	1.0	4.2	-0.2	0.5	-0.4	2.1	1.4	0.1	1.3	2.0	1.2	1.2	0.3	0.3	0.4	0.3
Schizophrenia (2018)	0.7	1.5	3.5	-1.4	1.8	0.9	0.1	0.8	1.7	0.8	0.3	1.2	1.3	1.8	1.9	-1.2	1.6
Age at First Birth	0.7	1.0	2.6	0.6	-1.4	-1.4	-1.3	-0.1	-1.6	1.1	-0.1	-0.7	-0.3	-1.4	-1.1	-0.6	-1.4
Mean Putamen Volume	0.7	0.8	4.5	1.1	0.0	0.5	1.1	1.2	0.2	2.1	1.4	1.2	-0.5	-0.0	0.3	0.6	-0.1
Primary Biliary Cirrhosis	0.7	1.0	4.4	1.3	-0.7	-0.4	-0.5	-1.5	-0.3	0.0	-1.4	-1.2	-2.1	-0.7	-1.4	0.1	-0.8
Allergy or Eczema	0.7	1.7	4.0	0.6	-2.0	-1.5	-1.0	-0.7	-1.8	-0.2	-0.5	-1.2	-1.0	-2.0	-1.9	1.4	-2.0
Other serious medical condition/disability diagnosed by doctor	0.7	0.8	2.5	1.4	-1.1	-1.0	-0.8	-0.5	-1.4	0.2	-0.2	-0.5	-0.6	-1.2	-0.5	1.6	-1.1
Age when periods started (menarche)	0.7	1.7	6.9	0.5	-1.1	-1.7	2.6	-1.6	-1.3	-2.4	-0.7	-1.1	-0.7	-1.1	-1.2	0.7	-1.1
Hayfever, allergic rhinitis or eczema	0.7	1.5	3.3	0.4	-1.8	-1.2	-0.7	-1.1	-1.7	-1.0	-0.9	-1.4	-0.8	-1.8	-1.7	0.9	-1.7
Alcohol usually taken with meals	0.7	1.1	4.1	0.5	-0.9	-0.3	-0.9	-1.8	-0.3	-0.5	-1.9	-1.5	-2.0	-0.8	-1.1	0.0	-0.9
Financial difficulties in last 2 years	0.7	1.0	2.2	1.3	-1.1	-0.7	-0.8	-0.9	-1.1	-0.3	-1.1	-1.3	-1.5	-1.2	-0.6	1.1	-1.3
Pain all over the body in last month	0.7	0.8	2.1	-1.3	1.2	1.5	0.9	0.4	1.3	0.2	0.0	0.5	0.5	1.2	1.0	-0.1	1.1
Noisy workplace	0.7	0.9	5.8	-0.1	-1.0	-2.4	-1.6	-0.1	-1.3	-0.9	0.5	-0.3	0.5	-0.9	-0.3	-0.1	-0.9
Length of working week for main job	0.7	0.8	3.2	0.4	0.0	1.1	-0.3	-1.5	0.6	-1.7	-1.8	-1.2	-1.0	0.0	-0.2	-0.6	0.0
Number of full brothers	0.7	0.9	2.4	-0.3	1.2	0.4	1.2	1.1	0.8	0.5	1.6	1.4	1.4	1.1	0.7	0.4	1.1
Medication: Ibuprofen	0.7	0.9	4.2	-1.1	-0.8	-0.5	-0.2	-1.3	-0.7	-1.0	-2.0	-1.8	-0.6	-0.7	-0.4	-0.3	-0.7
Medication: Omeprazole	0.7	0.8	3.6	-0.0	-1.1	-1.4	-0.9	0.0	-1.3	-0.1	0.2	-0.7	-0.4	-1.1	-0.3	1.9	-1.1
Suffer from ‘nerves’	0.7	1.0	6.8	-0.7	1.2	1.4	2.6	-0.0	1.2	-0.8	-0.2	0.6	0.8	1.1	0.7	0.2	1.2
Tinnitus: Yes, now most or all of the time	0.7	0.8	2.3	0.3	-1.1	-0.3	-0.5	-0.8	-1.1	-0.4	-1.2	-1.3	-1.1	-1.1	-1.5	-0.7	-1.1
Eye problems/disorders: Glaucoma	0.7	0.9	2.1	-0.9	0.6	1.1	1.2	1.4	0.4	1.4	1.3	0.9	1.2	0.5	1.1	-0.1	0.5
Supplements: Fish oil (including cod liver oil)	0.7	0.9	3.4	-0.7	0.6	0.2	0.4	1.6	-0.0	0.6	1.8	1.3	1.8	0.6	1.0	0.1	0.5
Ever had prostate specific antigen (PSA) test	0.7	0.8	2.2	0.9	-1.3	-0.3	-1.3	-0.4	-1.1	0.2	-0.4	-0.8	-1.5	-1.3	-0.8	0.6	-1.4
Cholesterol lowering medication	0.7	1.0	5.7	0.2	0.3	-0.8	0.4	1.2	0.1	0.7	1.9	1.4	1.0	0.3	0.8	2.4	0.3
Supplements: Calcium	0.7	0.8	5.9	0.3	-0.9	-0.4	-0.7	-0.8	-0.7	-0.5	-0.4	-0.5	-1.0	-1.0	-0.3	2.4	-1.0
Depressed Affect (Nagel 2018)	0.6	1.2	3.9	-0.9	1.6	2.0	0.7	0.2	1.6	-0.7	-0.3	0.4	0.9	1.5	1.7	0.2	1.6
Neuroticism (Nagel 2018)	0.6	1.4	3.6	-0.8	1.6	1.9	1.5	0.4	1.6	-0.5	-0.1	0.7	1.0	1.5	1.5	-0.3	1.8
Alzheimer’s Disease (in father)	0.6	0.7	2.7	1.0	1.2	1.0	-0.5	-0.2	1.6	0.9	-0.0	0.9	-0.5	1.2	0.4	-0.0	1.1
Lupus	0.6	0.8	2.6	-1.3	1.0	-1.4	0.6	0.0	0.6	-1.6	0.0	0.3	1.4	1.0	0.5	-1.0	1.0
Ulcerative Colitis	0.6	0.8	1.9	1.4	0.8	1.0	1.4	-1.1	1.2	-1.1	-0.2	0.9	-0.9	0.8	0.2	-0.9	0.9
Neuroticism	0.6	1.4	8.5	0.3	1.5	2.9	0.4	0.5	1.7	0.0	-0.1	0.8	0.2	1.5	1.5	-0.0	1.5
Ever had hysterectomy (womb removed)	0.6	0.7	1.9	-1.4	-0.5	-0.8	-0.7	-0.5	-1.0	-1.2	-1.1	-1.1	0.1	-0.5	-0.1	-1.1	-0.5
Heel bone mineral density (BMD) T-score, automated (left)	0.6	1.3	6.6	-2.6	0.8	1.1	-2.0	0.5	1.3	-0.3	-0.5	-0.0	0.9	1.0	1.5	0.4	1.0
Hearing difficulty/problems with background noise	0.6	0.9	3.5	-1.2	0.4	0.7	-0.3	1.9	0.1	1.0	1.6	0.8	1.4	0.3	1.0	1.2	0.4
Neuroticism score	0.6	1.2	5.5	-0.5	1.5	2.4	1.5	0.2	1.5	-0.1	-0.2	0.6	0.6	1.4	1.3	-0.4	1.5
Glaucoma (self-reported)	0.6	0.7	1.8	-0.3	1.0	0.8	1.1	0.6	0.9	0.4	1.0	1.4	0.8	0.9	1.2	0.1	0.9
Age at first live birth	0.6	1.0	3.7	-1.9	1.2	0.1	-0.6	-0.3	1.5	-1.1	-0.2	0.5	1.4	1.3	1.1	0.3	1.2
Had major operations	0.6	0.8	2.5	-1.0	-1.1	-1.6	0.2	-0.8	-1.0	-0.7	-0.7	-1.1	-0.8	-1.1	-0.6	0.4	-1.1
Age at last live birth	0.6	0.8	4.0	-2.0	0.7	-0.1	0.0	-0.8	0.8	-1.8	-0.8	-0.3	1.2	0.7	0.6	0.2	0.7
Medication: Aspirin	0.6	0.9	2.9	-1.3	0.7	-0.1	0.4	1.6	0.0	1.3	1.7	0.9	1.4	0.5	0.8	-0.2	0.5
Average weekly red wine intake	0.6	0.9	2.1	-0.6	-1.0	-1.5	-1.4	-1.0	-1.0	-1.4	-0.8	-1.0	-0.3	-1.0	-1.1	0.5	-1.1
Long-standing illness, disability or infirmity	0.6	1.0	2.9	1.4	-1.1	-1.7	-0.5	0.7	-1.7	1.0	0.9	-0.0	-0.3	-1.2	-0.6	0.6	-1.2
Smoking status: Current	0.6	1.0	5.1	0.7	-1.2	-0.6	-2.3	-0.1	-1.3	0.1	-0.2	-1.0	-0.8	-1.2	-0.8	1.3	-1.2
Unable to work because of sickness or disability	0.6	0.7	2.1	-0.8	0.6	0.7	0.8	1.2	0.4	1.5	0.9	0.8	0.8	0.6	1.2	1.2	0.5
Ulcerative Colitis (UC)	0.5	1.0	4.4	1.1	0.9	0.2	1.9	-0.5	1.4	-0.4	0.1	1.1	-0.5	1.0	0.3	-2.1	1.1
Ever used hormone-replacement therapy (HRT)	0.5	0.7	2.0	-0.5	-0.7	-0.9	1.3	-0.9	-0.8	-1.4	-0.8	-0.9	-0.7	-0.7	-0.6	0.9	-0.7
Vitamin and mineral supplements	0.5	0.7	2.7	-1.0	0.1	0.2	-0.3	1.4	-0.1	1.6	1.6	1.1	0.7	0.1	0.6	0.3	0.1
Medication: Co-codamol	0.5	0.5	3.6	0.7	-0.5	-1.9	0.8	-0.6	-0.9	-0.3	-0.4	-0.6	-0.5	-0.7	-0.7	0.1	-0.7
Current tobacco smoking	0.5	0.8	4.0	0.4	-1.1	-0.4	-2.0	0.2	-1.2	0.5	0.1	-0.8	-0.4	-1.1	-0.6	1.4	-1.1
Maternal smoking around birth	0.5	0.7	1.6	1.0	-1.0	-0.2	-0.2	-1.2	-0.8	-0.7	-1.2	-0.8	-1.3	-0.9	-0.7	-1.1	-0.9
Qualifications: CSEs or equivalent	0.5	0.6	1.4	-0.3	1.1	0.2	-0.2	0.4	1.1	-0.5	0.6	0.7	1.2	1.2	1.1	-0.9	1.2
Serious illness, injury or assault to yourself	0.5	0.7	3.0	1.5	-0.7	-0.3	1.7	-0.5	-0.8	-0.1	-0.4	-0.7	-0.7	-0.8	-1.0	-0.5	-0.8
Had other major operations	0.5	0.6	2.0	-0.9	1.0	0.8	0.5	0.6	0.9	0.2	0.3	0.6	0.8	1.0	0.8	-1.4	1.0
Qualifications: None of the above	0.5	1.1	9.1	0.1	0.4	-0.1	1.4	1.0	0.4	0.5	1.5	1.1	0.7	0.4	0.3	3.0	0.4
Number of live births	0.5	0.7	2.7	0.6	0.1	0.4	1.1	1.4	-0.1	1.6	1.6	1.1	0.6	0.1	0.1	0.1	0.1
Qualifications: O levels/GCSEs or equivalent	0.5	0.9	2.8	0.4	-0.9	-1.7	-0.6	-1.3	-0.7	-0.6	-1.3	-1.0	-1.0	-0.8	-0.6	-1.4	-0.8
Neck or shoulder pain in last month	0.5	0.7	3.0	-1.5	0.8	-0.9	1.7	-0.1	0.5	-0.8	0.0	0.3	0.5	0.8	0.3	-1.5	0.7
Loneliness, isolation	0.5	0.7	3.8	-0.2	0.8	1.2	1.6	0.4	0.7	0.4	-0.1	0.1	0.5	0.8	0.5	-1.9	0.8
Guilty feelings	0.5	0.7	2.4	-1.4	-0.4	1.6	0.9	-0.4	-0.3	-1.1	-1.2	-1.4	0.2	-0.4	-0.4	-0.9	-0.4
Wears glasses or contact lenses	0.5	0.6	4.1	-2.0	-0.1	-1.0	-0.4	0.2	-0.5	-0.1	0.3	-0.1	1.1	-0.1	0.8	1.4	-0.2
Hearing aid user	0.5	0.6	1.8	-1.4	0.6	-0.3	0.7	1.0	0.3	1.0	0.5	0.2	1.4	0.5	1.1	0.8	0.5
Medication: Lisinopril	0.5	0.7	7.5	0.7	0.7	-0.2	-0.1	-0.5	0.7	0.2	-0.8	0.0	-0.6	0.7	0.5	-2.7	0.6
Diastolic blood pressure, automated reading	0.5	1.6	5.9	-0.4	1.8	1.8	0.7	0.3	2.4	1.0	0.2	1.1	-0.4	1.9	1.9	0.5	1.9
Ever depressed for a whole week	0.5	0.7	1.8	-1.2	-1.1	-0.1	0.0	-0.3	-1.4	-0.8	-0.9	-1.3	-0.0	-1.1	-0.5	-0.2	-1.1
Commuting to job workplace: Cycle	0.5	0.6	1.8	0.3	-0.9	-0.8	-1.2	0.1	-1.2	0.6	0.2	-0.4	0.2	-1.0	-0.5	1.3	-0.9
Depression (Nagel 2018)	0.4	0.6	1.8	-0.3	1.1	1.2	1.4	0.5	0.8	0.1	-0.1	0.4	0.5	1.0	0.9	-1.1	1.0
Ovarian Cancer	0.4	0.6	2.1	0.2	1.2	0.8	1.2	-0.2	1.4	0.2	-0.2	0.7	-0.0	1.1	0.9	0.3	1.1
HbA1C	0.4	0.5	2.4	0.5	-0.7	0.7	-0.3	0.2	-0.8	-0.0	-0.5	-0.6	-0.7	-0.8	-0.7	1.1	-1.6
LDL Cholesterol	0.4	0.7	3.2	0.2	0.9	1.5	1.5	-0.2	0.9	-0.3	-0.1	0.7	0.1	0.8	0.2	-1.8	0.8
Systolic blood pressure, automated reading	0.4	1.2	4.5	-0.2	1.4	1.5	0.6	-0.7	2.1	0.2	-1.1	0.3	-1.4	1.5	1.4	-0.3	1.4
Medication for hormone replacement therapy	0.4	0.5	1.3	-0.5	0.8	1.1	0.6	0.9	0.6	1.1	0.4	0.5	0.6	0.7	0.6	-0.3	0.8
Pack years adult smoking proportion	0.4	0.5	4.2	-0.9	-0.7	-0.6	-0.8	0.2	-0.7	0.8	-0.0	-0.4	0.2	-0.7	0.2	2.1	-0.6
Fed-up feelings	0.4	0.7	2.2	-1.1	1.1	1.5	0.6	0.6	0.9	-0.1	-0.0	0.1	1.0	1.1	1.2	-0.2	1.1
Past tobacco smoking	0.4	0.7	3.3	0.3	1.1	0.3	1.8	0.2	1.2	0.4	0.4	0.8	0.4	1.1	0.6	-0.9	1.1
Ever unenthusiastic/disinterested for a whole week	0.4	0.5	4.9	-2.2	-0.0	0.1	0.5	0.9	-0.4	0.3	0.9	0.4	0.9	-0.0	0.4	0.7	0.0
Mouth/teeth dental problems	0.4	0.6	1.8	0.2	-1.2	-0.7	-0.6	0.5	-1.4	0.9	0.7	-0.1	-0.2	-1.1	-0.4	1.2	-1.1
Depression (self-reported)	0.4	0.4	3.8	-0.5	0.5	0.7	1.9	0.1	0.6	-0.1	-0.2	0.3	0.2	0.5	0.8	0.7	0.5
Pulse wave reflection index	0.4	0.5	2.6	-0.1	0.2	0.2	-0.1	1.6	-0.2	0.9	1.1	0.5	1.4	0.3	0.4	-1.2	0.3
Loud music exposure frequency	0.4	0.4	2.3	-1.5	-0.2	0.9	-0.1	0.6	-0.3	1.4	-0.2	-0.2	0.8	-0.2	0.3	-0.2	-0.1
Chronic bronchitis/emphysema (mother)	0.4	0.4	3.4	0.4	-0.0	-0.1	0.8	-1.1	0.2	-1.8	-1.1	-0.5	-0.5	-0.0	0.2	0.1	0.0
Number of children fathered	0.4	0.4	3.6	0.8	-0.0	-0.6	-1.9	-0.5	0.2	-0.3	-0.1	-0.1	-0.4	0.1	0.1	-1.4	0.1
Health satisfaction	0.4	0.5	2.9	-1.0	0.7	-0.2	0.5	0.6	0.5	0.0	0.3	0.4	0.9	0.7	1.1	-1.7	0.7
Qualifications: College or University degree	0.4	1.3	4.3	-0.7	-1.6	-0.1	-2.1	-0.7	-1.6	0.5	-1.0	-1.5	-0.7	-1.6	-1.3	-0.4	-1.6
Emphysema/chronic bronchitis	0.4	0.4	1.8	-1.3	0.6	0.0	1.1	0.5	0.6	0.2	0.7	0.9	0.3	0.6	0.8	0.5	0.6
Alcohol intake frequency.	0.4	0.9	10.8	3.3	-0.0	0.1	-0.2	0.1	-0.1	1.0	0.2	-0.0	-1.5	-0.2	-0.3	0.2	-0.2
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.4	1.5	0.2	-0.4	-0.7	-0.3	-1.1	-0.1	-1.0	-1.1	-0.7	-1.2	-0.4	-0.4	0.6	-0.4
Supplements: Vitamin C	0.4	0.5	2.2	1.5	-0.2	0.2	-0.6	-0.6	0.1	-0.4	-1.1	-0.8	-1.0	-0.2	-0.8	-0.7	-0.2
Handedness (chirality/laterality): Left-handed	0.4	0.5	1.5	1.2	1.0	0.8	-0.3	-0.2	1.2	-1.0	-0.2	0.6	0.0	1.0	0.5	-0.1	0.9
Mouth/teeth dental problems: Mouth ulcers	0.4	0.7	3.6	0.9	0.1	1.1	-0.6	-0.8	0.4	-0.2	-1.5	-0.6	-1.1	-0.0	-0.8	-1.9	0.0
Breast cancer (self-reported)	0.4	0.5	1.5	0.2	1.0	1.1	-0.0	0.2	1.2	0.1	0.4	0.8	1.1	1.0	0.7	-0.4	1.0
Medication: Aspirin	0.4	0.5	2.2	-0.7	0.2	-0.5	0.4	1.3	-0.4	1.1	1.5	0.7	1.0	0.1	0.3	-0.9	0.1
Miserableness	0.4	0.8	3.0	-1.0	1.0	1.6	0.7	0.3	1.1	-0.2	-0.3	0.0	0.7	0.9	1.7	0.8	1.0
Financial situation satisfaction	0.4	0.5	1.2	1.0	-0.8	-0.3	0.5	-0.4	-0.9	0.4	-0.9	-1.1	-0.8	-0.9	-0.3	0.2	-0.9
Irritability	0.4	0.7	2.4	-1.4	0.7	1.1	0.8	1.1	0.5	1.5	0.5	0.2	1.2	0.7	0.7	-0.7	0.7
Risk taking	0.4	0.7	1.3	-0.4	-1.1	-0.7	-0.1	-0.8	-0.7	-0.7	-1.1	-1.1	-1.2	-1.1	-0.4	0.8	-1.0
Alcohol drinker status: Previous	0.4	0.5	2.0	1.4	-0.7	-0.3	0.1	0.0	-0.7	0.8	0.3	0.2	-0.9	-0.8	-0.7	1.1	-0.9
Pack years of smoking	0.4	0.6	4.3	-1.1	-0.6	-0.7	-0.6	0.3	-0.7	0.7	0.1	-0.3	0.3	-0.6	0.3	2.1	-0.6
Schizophrenia vs Biploar Disorder	0.3	0.4	3.5	-1.2	-0.2	0.2	-1.9	0.1	-0.0	-0.2	-0.2	-0.2	-0.1	-0.2	0.0	1.2	-0.3
Prostate Cancer	0.3	0.4	1.7	-0.7	-0.1	-0.2	-1.3	-0.6	-0.2	-0.5	-1.1	-0.7	-0.5	-0.1	0.5	-1.3	0.0
Bipolar Disorder (2011)	0.3	0.3	0.8	-0.2	0.1	0.1	-0.3	0.9	-0.0	0.4	0.8	0.7	0.7	0.2	0.7	0.8	0.4
Blood Eosinophil Count	0.3	2.5	6.1	2.3	-2.1	-0.9	-0.0	-0.8	-2.0	0.4	0.6	-0.2	-2.2	-2.2	-2.5	1.7	-2.2
Average weekly spirits intake	0.3	0.3	2.8	1.7	-0.3	0.2	-0.4	0.8	-0.2	0.8	0.6	0.1	-0.3	-0.2	0.4	0.4	-0.2
Supplements: Zinc	0.3	0.4	2.5	1.1	0.3	-0.2	0.7	-0.1	0.6	0.2	0.3	0.7	-0.3	0.4	0.6	1.6	0.4
Severe depression (siblings)	0.3	0.3	1.6	-0.6	0.1	-0.8	1.2	-0.2	-0.3	-0.8	-0.3	-0.4	0.6	-0.0	-0.1	-1.3	-0.0
Average weekly fortified wine intake	0.3	0.4	1.7	0.8	-0.6	-0.9	-0.6	0.4	-0.7	1.3	0.4	-0.1	-0.1	-0.5	-0.3	1.0	-0.6
Relative age voice broke	0.3	0.5	2.0	-0.3	-0.7	-1.4	1.0	-0.3	-0.9	-1.1	-0.2	-0.8	0.5	-0.7	-0.9	-0.1	-0.7
Multivitamins +/- minerals	0.3	0.4	1.1	0.0	0.8	0.5	1.0	-0.6	0.9	-1.1	-1.0	-0.1	0.3	0.8	0.3	-0.7	0.8
Had menopause	0.3	0.4	2.4	-1.1	0.5	-0.0	1.6	0.1	0.3	-0.8	0.2	0.4	0.2	0.5	0.7	-0.4	0.5
Father’s age at death	0.3	0.4	1.4	0.3	0.5	0.8	-0.7	0.2	0.6	0.1	0.4	0.7	0.2	0.5	1.1	1.2	0.5
Medication: Cholesterol lowering	0.3	0.4	1.0	-0.4	0.8	0.9	0.9	0.1	0.9	0.4	0.3	0.8	-0.0	0.7	1.0	0.5	0.7
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.5	1.5	-1.2	0.5	0.5	-1.2	0.6	0.2	-0.5	0.5	0.5	0.8	0.3	0.7	1.2	0.4
Medication: Allopurinol	0.3	0.4	2.0	-0.7	-0.4	1.1	-1.4	0.4	-0.3	1.2	-0.3	-0.6	-0.5	-0.4	-0.0	-0.6	-0.4
Overall health rating	0.3	0.6	2.2	0.2	0.5	0.2	0.9	1.3	-0.0	1.5	1.2	0.8	0.9	0.4	0.9	-0.2	0.4
Family relationship satisfaction	0.3	0.4	1.3	1.1	-0.8	-0.0	0.6	-0.3	-1.0	-0.2	-0.5	-0.4	-0.3	-0.8	-0.7	-0.7	-0.8
Smoking status: Previous	0.3	0.5	1.9	-0.7	-0.9	-0.3	-1.4	-0.1	-1.0	-0.2	-0.4	-0.8	-0.1	-0.9	-0.3	0.4	-0.9
Ever had bowel cancer screening	0.3	0.3	0.7	-0.3	-0.8	-0.4	-0.0	-0.6	-0.8	-0.6	-0.5	-0.7	-0.5	-0.8	-0.3	0.2	-0.8
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.3	1.8	1.1	0.1	0.4	-0.9	-0.4	0.5	0.1	-0.3	0.2	-0.7	0.2	-0.0	1.3	0.2
Average weekly champagne plus white wine intake	0.3	0.4	2.0	-0.7	0.5	0.2	0.9	0.5	0.5	1.4	0.5	0.5	0.5	0.5	0.6	0.3	0.5
Medication: Bendroflumethiazide	0.3	0.5	3.8	-0.3	0.7	0.9	0.6	0.4	0.7	0.2	-0.1	0.2	0.0	0.7	0.3	-2.0	0.7
Leg fat percentage (left)	0.3	1.1	3.5	0.4	-1.5	-1.4	-0.7	-0.1	-1.9	0.1	0.0	-1.1	-0.5	-1.5	-1.1	1.2	-1.5
Medication: Omeprazole (e.g. Zanprol)	0.3	0.4	2.8	-0.8	0.1	-0.1	-0.4	1.0	-0.1	0.6	0.9	0.2	0.6	0.0	0.8	1.7	0.0
Breast Cancer	0.2	0.6	2.0	-1.4	0.4	0.4	0.8	0.6	0.7	-0.5	1.1	0.9	0.3	0.5	0.9	1.3	0.5
Blood Red Count	0.2	2.1	7.7	-0.6	2.3	1.6	0.6	0.0	2.8	0.1	-0.2	1.1	0.3	2.4	1.7	-1.5	2.3
Waist Hip Ratio (WHR)	0.2	1.1	4.3	0.8	-0.3	-1.0	-1.2	1.4	-0.6	1.3	2.1	1.2	0.9	-0.3	0.2	1.8	-0.3
Frequency of depressed mood in last 2 weeks	0.2	0.3	1.1	-1.0	0.2	0.4	0.4	1.0	-0.2	0.9	0.2	0.1	0.9	0.2	0.5	-1.1	0.2
Townsend deprivation index at recruitment	0.2	0.3	1.5	-1.1	0.4	0.8	1.2	0.1	0.5	0.0	-0.2	0.1	0.9	0.4	0.2	0.6	0.4
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.3	1.8	0.5	0.3	0.4	1.3	0.8	0.0	0.9	0.7	0.6	0.6	0.3	0.4	-0.3	0.2
Tinnitus: Yes, but not now, but have in the past	0.2	0.2	1.8	-1.3	-0.2	0.3	-0.4	0.3	-0.2	0.3	0.0	-0.0	0.6	-0.2	0.3	0.3	-0.1
Supplements: Glucosamine	0.2	0.3	1.2	-1.0	-0.3	-1.1	-0.3	-0.2	-0.8	-0.5	-0.5	-0.5	0.9	-0.3	0.1	-0.3	-0.4
Medication: Atenolol	0.2	0.2	0.7	0.6	0.4	0.6	-0.1	0.2	0.7	0.3	0.2	0.6	-0.5	0.4	0.4	0.8	0.4
Medication: Simvastatin	0.2	0.3	0.9	0.7	-0.3	-0.9	0.5	0.1	-0.5	0.5	0.7	0.5	0.1	-0.3	0.1	1.0	-0.4
Alcohol intake versus 10 years previously	0.2	0.3	1.5	1.2	0.3	0.4	1.1	-0.2	0.2	-0.1	-0.2	0.2	-0.7	0.2	-0.1	-0.9	0.2
Worrier / anxious feelings	0.2	0.5	1.9	1.4	0.6	0.9	-0.8	-0.8	0.9	-0.6	-0.9	-0.2	-0.8	0.5	0.2	-0.2	0.5
Mouth/teeth dental problems: Dentures	0.2	0.4	2.1	-0.9	-0.1	-0.1	1.4	-0.8	-0.1	-0.9	-0.8	-0.5	-0.7	-0.1	-0.4	-0.3	-0.2
Hair/balding pattern: Pattern 4	0.2	0.5	1.1	0.6	-0.9	-0.1	0.7	-0.8	-0.7	-0.6	-0.6	-0.8	-1.0	-0.8	-0.7	0.3	-0.8
Leg fat percentage (right)	0.2	0.9	3.1	0.1	-1.4	-1.0	-0.5	0.2	-1.8	0.6	0.2	-0.9	-0.2	-1.4	-0.9	1.5	-1.4
Comparative body size at age 10	0.2	0.5	3.0	-0.7	-0.2	0.3	-1.1	1.3	-0.4	1.7	0.8	0.4	0.6	-0.1	0.3	0.5	-0.2
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.2	0.8	-0.8	0.5	0.9	-0.6	-0.5	0.7	0.0	-0.5	0.1	-0.5	0.5	-0.0	-0.3	0.5
Medication: Blood pressure	0.2	0.3	1.0	0.4	0.1	-0.2	0.2	-0.7	0.4	-0.6	-0.9	-0.5	-0.7	0.1	0.6	1.0	0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.2	0.3	1.5	-1.2	0.2	0.5	-0.8	0.5	0.2	0.5	-0.1	-0.3	0.4	0.2	-0.0	-1.2	0.2
Pulse rate, automated reading	0.2	0.7	2.3	-1.3	-0.8	-1.4	0.8	0.6	-1.5	1.2	0.7	-0.2	0.8	-0.8	0.2	0.1	-0.8
Chest pain or discomfort	0.2	0.3	1.8	1.3	-0.6	-0.5	0.4	-0.2	-0.8	-0.2	0.0	-0.2	-0.4	-0.8	-0.7	0.3	-0.7
Commuting to job workplace: Walk	0.2	0.2	1.6	-0.3	0.1	0.3	-0.9	0.4	-0.0	0.8	0.4	0.4	0.1	0.1	-0.3	-1.3	0.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.2	0.8	-0.6	0.1	-0.9	0.7	0.4	-0.1	0.2	0.8	0.5	0.7	0.1	0.6	0.2	0.1
Pain type(s) experienced in last month: Hip pain	0.2	0.3	0.8	0.7	-0.6	-0.0	0.6	-0.5	-0.5	0.0	0.0	-0.2	-0.9	-0.6	-0.6	0.7	-0.5
High cholesterol (Self-reported)	0.2	0.4	2.0	0.1	0.9	0.2	1.4	-0.1	1.0	-0.4	-0.1	0.7	0.1	0.9	0.9	0.2	0.9
Ever smoked	0.2	0.4	2.2	-0.3	-0.6	0.5	-1.5	-0.2	-0.5	-0.4	-0.5	-0.7	-0.2	-0.6	-0.1	1.2	-0.5
Average weekly beer plus cider intake	0.2	0.3	1.5	-0.6	0.5	-0.2	0.7	-0.1	0.1	-1.2	-0.1	0.3	0.4	0.4	0.3	-1.1	0.5
Impedance of whole body	0.2	1.1	3.0	-1.4	1.3	1.1	1.1	0.9	1.3	-0.5	1.2	1.3	1.7	1.2	0.7	-0.1	1.3
Reaction Time	0.1	0.2	0.5	-0.0	0.6	0.6	-0.6	0.0	0.6	0.7	-0.1	0.4	0.1	0.5	0.4	0.2	0.5
Triglycerides	0.1	0.1	0.4	0.6	0.2	0.5	0.5	0.0	0.3	0.4	0.2	0.7	-0.2	0.1	0.6	0.4	0.3
Hair Pigment	0.1	2.3	5.5	1.7	-2.4	-1.4	-1.8	-0.7	-2.4	-0.6	-0.3	-1.3	-1.4	-2.3	-1.6	0.6	-2.2
Sensitivity / hurt feelings	0.1	0.2	1.1	0.1	-0.4	1.0	-0.2	-0.1	-0.5	-0.2	-0.7	-0.5	-0.6	-0.5	-0.4	-0.2	-0.5
Impedance of arm (right)	0.1	0.7	5.3	-2.3	0.4	0.4	1.1	0.3	0.1	-0.9	0.1	-0.0	1.4	0.3	0.1	-1.0	0.3
Frequency of tiredness / lethargy in last 2 weeks	0.1	0.2	1.1	-0.1	-0.1	0.1	1.0	-0.3	-0.4	-0.7	-0.7	-0.7	0.2	-0.1	0.1	-0.5	-0.2
Qualifications: A levels/AS levels or equivalent	0.1	0.3	0.6	0.1	-0.7	-0.7	0.4	-0.6	-0.8	0.3	-0.6	-0.8	-0.7	-0.7	-0.4	-0.4	-0.7
Impedance of arm (left)	0.1	0.4	2.1	-1.1	-0.3	-0.2	-0.3	-0.2	-0.5	-1.4	-0.2	-0.5	0.9	-0.3	-0.5	-1.3	-0.3
Worry too long after embarrassment	0.1	0.2	1.9	-1.4	-0.0	0.1	0.5	-0.1	-0.2	-0.7	0.1	0.0	0.7	-0.0	0.1	-0.4	0.1
Mouth/teeth dental problems: Loose teeth	0.1	0.1	0.8	-0.3	-0.1	-0.3	-0.6	-0.7	-0.2	-0.9	-0.2	-0.3	-0.2	-0.2	-0.2	-0.4	-0.2
Mean time to correctly identify matches	0.1	0.2	1.4	0.2	-0.5	-0.2	-1.2	0.1	-0.8	0.5	0.0	-0.2	-0.2	-0.6	-0.4	0.3	-0.6
Mineral and other dietary supplements	0.1	0.1	0.8	-0.0	0.0	0.9	-0.1	0.1	0.5	0.7	-0.1	-0.2	-0.8	0.1	-0.2	-0.2	0.1
Blood Platelet Count	0.0	0.4	1.3	1.1	-0.7	0.7	-0.4	0.3	-0.6	0.4	0.5	0.0	-0.5	-0.8	-1.0	-0.2	-0.8
Tanning	0.0	0.2	2.2	0.1	-0.1	0.1	-1.5	-0.3	-0.1	-0.1	-0.4	-0.3	-0.2	-0.1	0.1	-0.6	-0.0
Medication for cholesterol, blood pressure or diabetes	0.0	0.1	0.5	-0.2	-0.1	-0.1	0.2	0.4	-0.3	-0.1	0.6	0.2	0.7	-0.0	-0.3	-0.3	-0.0

Hub : Genes

PLEKHA1

Models

Trait associations