[Hub]/) : Traits : Trunk fat mass :

chr10:130,566,749-132,263,732

Best TWAS P=4.18e-09 · Best GWAS P=1.15e-07 conditioned to 0.655

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex MGMT 0.29 0.27 lasso 14 0.31 6.0e-38 -5.2 5.4 6.4e-08 -0.89 0.00 1.00 FALSE
2 GTEx Adrenal Gland MGMT 0.39 0.25 lasso 6 0.30 1.5e-11 -5.2 5.5 3.9e-08 -0.95 0.01 0.99 FALSE
3 GTEx Brain Cerebellar Hemisphere MGMT 0.53 0.15 lasso 8 0.19 1.3e-05 -5.2 5.9 4.2e-09 -0.93 0.01 0.97 TRUE
4 GTEx Breast Mammary Tissue MGMT 0.60 0.21 enet 13 0.33 1.6e-17 -5.0 5.2 2.6e-07 -0.88 0.01 0.99 FALSE
5 GTEx Cells Transformed fibroblasts MGMT 0.45 0.30 enet 31 0.42 4.8e-34 -4.7 5.7 1.5e-08 -0.85 0.04 0.96 FALSE
6 GTEx Colon Transverse MGMT 0.47 0.24 enet 58 0.35 1.6e-17 -5.0 5.7 1.6e-08 -0.75 0.02 0.97 FALSE
7 GTEx Esophagus Gastroesophageal Junction MGMT 0.34 0.31 lasso 6 0.28 9.8e-11 -4.8 5.1 2.9e-07 -0.82 0.02 0.98 FALSE
8 GTEx Esophagus Mucosa MGMT 0.41 0.33 enet 37 0.38 2.3e-26 -5.0 5.6 2.7e-08 -0.82 0.02 0.98 FALSE
9 GTEx Heart Atrial Appendage MGMT 0.41 0.17 enet 33 0.22 4.6e-10 -5.0 5.6 2.7e-08 -0.87 0.01 0.99 FALSE
10 GTEx Liver MGMT 0.46 0.39 lasso 4 0.42 8.2e-13 -5.0 5.2 1.7e-07 -0.84 0.02 0.98 FALSE
11 GTEx Ovary MGMT 0.52 0.09 enet 59 0.12 8.6e-04 -4.7 5.6 2.4e-08 -0.65 0.03 0.94 FALSE
12 GTEx Prostate MGMT 0.25 0.13 lasso 4 0.20 9.4e-06 -5.2 5.7 1.0e-08 -0.90 0.02 0.95 FALSE
13 GTEx Skin Sun Exposed Lower leg MGMT 0.45 0.30 enet 42 0.46 1.6e-41 -4.8 5.7 1.2e-08 -0.85 0.02 0.98 FALSE
14 GTEx Stomach MGMT 0.33 0.20 enet 9 0.25 2.3e-12 -5.1 5.5 2.9e-08 -0.93 0.01 0.99 FALSE
15 GTEx Thyroid MGMT 0.44 0.35 lasso 11 0.43 1.9e-35 -5.2 5.4 5.4e-08 -0.92 0.01 0.99 FALSE
16 GTEx Vagina MGMT 0.33 0.23 lasso 4 0.24 3.3e-06 -4.7 5.2 2.2e-07 -0.79 0.04 0.84 FALSE
17 NTR Blood MGMT 0.08 0.07 lasso 8 0.08 3.7e-24 -5.0 5.2 2.3e-07 -0.86 0.02 0.98 FALSE
18 ROSMAP Brain Pre-frontal Cortex MGMT 0.41 0.38 enet 46 0.48 3.6e-69 -5.0 5.5 3.7e-08 -0.87 0.01 0.99 FALSE
19 YFS Blood MGMT 0.50 0.40 enet 94 0.55 1.6e-218 -5.0 5.3 1.3e-07 -0.81 0.02 0.98 FALSE
20 The Cancer Genome Atlas Breast Invasive Carcinoma MGMT 0.16 0.17 enet 22 0.21 2.4e-41 -5.0 5.1 3.1e-07 -0.89 0.01 0.98 FALSE
21 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma MGMT 0.18 0.03 blup 239 0.12 2.3e-06 -5.0 5.2 1.8e-07 -0.75 0.03 0.96 FALSE
22 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma MGMT 0.10 0.09 enet 23 0.10 1.9e-11 -4.7 5.4 7.6e-08 -0.74 0.06 0.93 FALSE
23 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma MGMT 0.26 0.32 lasso 10 0.37 2.9e-43 -5.3 5.4 6.7e-08 -0.94 0.00 1.00 FALSE
24 The Cancer Genome Atlas Liver Hepatocellular Carcinoma MGMT 0.25 0.05 blup 234 0.12 1.9e-06 -5.0 5.3 1.4e-07 -0.62 0.02 0.95 FALSE