Best TWAS P=1.33e-09 · Best GWAS P=1.99e-10 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Pituitary | DPYSL4 | 0.24 | 0.11 | lasso | 4 | 0.26 | 3.0e-07 | 3.6 | 5.7 | 1.2e-08 | 0.63 | 0.02 | 0.81 | FALSE |
| 2 | The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | DPYSL4 | 0.31 | 0.19 | lasso | 10 | 0.18 | 3.4e-09 | 6.0 | 5.7 | 1.4e-08 | 0.91 | 0.00 | 1.00 | FALSE |
| 3 | The Cancer Genome Atlas | Glioblastoma Multiforme | STK32C | 0.13 | -0.01 | blup | 107 | 0.08 | 1.6e-03 | 3.0 | -5.8 | 7.4e-09 | -0.35 | 0.04 | 0.07 | TRUE |
| 4 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | DPYSL4 | 0.16 | 0.21 | enet | 16 | 0.24 | 7.1e-27 | 6.0 | 5.3 | 1.5e-07 | 0.91 | 0.00 | 1.00 | FALSE |
| 5 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | DPYSL4 | 0.17 | 0.24 | lasso | 3 | 0.23 | 2.4e-13 | 6.3 | 6.1 | 1.3e-09 | 0.98 | 0.00 | 1.00 | TRUE |
| 6 | The Cancer Genome Atlas | Brain Lower Grade Glioma | DPYSL4 | 0.13 | 0.12 | lasso | 7 | 0.16 | 3.1e-17 | 6.3 | 5.5 | 3.0e-08 | 0.93 | 0.00 | 1.00 | FALSE |
| 7 | The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | DPYSL4 | 0.13 | 0.11 | enet | 7 | 0.08 | 2.0e-04 | 6.0 | 6.0 | 2.0e-09 | 0.96 | 0.02 | 0.97 | FALSE |
| 8 | The Cancer Genome Atlas | Lung Adenocarcinoma | DPYSL4 | 0.17 | 0.16 | enet | 18 | 0.23 | 1.5e-26 | 6.4 | 5.4 | 7.6e-08 | 0.86 | 0.00 | 1.00 | FALSE |
| 9 | The Cancer Genome Atlas | Lung Adenocarcinoma | GPR123 | 0.05 | 0.00 | blup | 56 | 0.02 | 8.0e-04 | 3.5 | 5.9 | 4.0e-09 | 0.00 | 0.00 | 0.19 | TRUE |
| 10 | The Cancer Genome Atlas | Prostate Adenocarcinoma | DPYSL4 | 0.34 | 0.37 | enet | 15 | 0.46 | 2.2e-53 | -5.5 | 5.3 | 1.4e-07 | 0.92 | 0.01 | 0.99 | FALSE |