Best TWAS P=4.77e-16 · Best GWAS P=1.56e-29 conditioned to 0.00305
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Mucosa | CERS5 | 0.08 | 0.00 | enet | 23 | 0.01 | 6.4e-02 | -2.39 | 5.3 | 1.1e-07 | 0.23 | 0.26 | 0.27 | FALSE |
| 2 | GTEx | Lung | CERS5 | 0.07 | 0.06 | enet | 12 | 0.07 | 2.8e-06 | -2.92 | 5.4 | 7.4e-08 | 0.29 | 0.92 | 0.07 | TRUE |
| 3 | GTEx | Testis | FAIM2 | 0.27 | 0.09 | lasso | 5 | 0.06 | 9.3e-04 | 8.82 | -8.1 | 4.8e-16 | -0.77 | 0.04 | 0.85 | TRUE |
| 4 | The Cancer Genome Atlas | Breast Invasive Carcinoma | FAIM2 | 0.02 | 0.00 | blup | 71 | 0.01 | 8.5e-03 | 0.01 | -6.0 | 1.6e-09 | -0.36 | 0.16 | 0.13 | TRUE |