Best TWAS P=3.6e-08 · Best GWAS P=1.1e-08 conditioned to 0.00107
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | YFS | Blood | TTC38 | 0.15 | 0.12 | enet | 35 | 0.21 | 4.5e-67 | 4.9 | -5.2 | 1.5e-07 | -0.53 | 0.14 | 0.85 | FALSE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | TTC38 | 0.07 | 0.02 | lasso | 7 | 0.07 | 2.6e-14 | 5.0 | -5.5 | 3.6e-08 | -0.54 | 0.09 | 0.90 | TRUE |
| 3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | TRMU | 0.05 | 0.03 | blup | 45 | 0.04 | 3.0e-05 | 4.6 | 5.3 | 1.2e-07 | 0.63 | 0.01 | 0.98 | FALSE |
| 4 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | TTC38 | 0.12 | 0.09 | enet | 17 | 0.13 | 6.0e-15 | -2.7 | -5.4 | 7.3e-08 | -0.45 | 0.93 | 0.01 | FALSE |