Best TWAS P=1.18e-07 · Best GWAS P=9.14e-08 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cerebellum | EXOSC10 | 0.33 | 0.16 | lasso | 6 | 0.18 | 3.8e-06 | 4.6 | 5.1 | 2.6e-07 | 0.93 | 0.05 | 0.94 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | MTOR | 0.07 | 0.05 | bslmm | 423 | 0.04 | 2.0e-06 | 4.6 | 5.3 | 1.2e-07 | 0.87 | 0.08 | 0.91 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | MTOR | 0.02 | 0.02 | blup | 54 | 0.02 | 5.4e-03 | 5.3 | 5.3 | 1.2e-07 | 0.97 | 0.02 | 0.88 | TRUE |