[Hub]/) : Traits : Trunk fat mass :

chr2:68,850,921-70,593,838

Best TWAS P=8.89e-13 · Best GWAS P=3.52e-11 conditioned to 0.419

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous GFPT1 0.07 0.04 enet 11 0.01 6.9e-02 -6.5 5.3 1.1e-07 -0.80 0.03 0.96 FALSE
2 GTEx Adrenal Gland NFU1 0.23 0.15 lasso 23 0.19 2.9e-07 -6.4 5.3 9.9e-08 -0.91 0.06 0.94 FALSE
3 GTEx Artery Tibial GFPT1 0.09 0.05 lasso 4 0.02 1.1e-02 -6.6 6.6 5.4e-11 -0.99 0.02 0.98 FALSE
4 GTEx Cells Transformed fibroblasts AAK1 0.08 0.05 lasso 5 0.03 1.4e-03 -6.4 -6.5 1.1e-10 0.96 0.03 0.97 FALSE
5 GTEx Cells Transformed fibroblasts NFU1 0.10 0.07 lasso 2 0.03 2.0e-03 5.1 -5.1 2.7e-07 0.40 0.49 0.03 FALSE
6 GTEx Colon Transverse AAK1 0.07 0.07 lasso 2 0.05 2.1e-03 -6.0 -5.8 8.3e-09 0.89 0.06 0.84 FALSE
7 GTEx Colon Transverse GFPT1 0.20 0.23 lasso 4 0.22 4.9e-11 -6.5 5.6 1.7e-08 -0.92 0.02 0.98 FALSE
8 GTEx Esophagus Muscularis GFPT1 0.13 0.01 enet 32 0.04 2.0e-03 -6.5 5.2 2.1e-07 -0.74 0.02 0.97 FALSE
9 GTEx Muscle Skeletal GFPT1 0.08 0.00 lasso 8 0.00 2.2e-01 -6.5 5.8 8.8e-09 -0.84 0.03 0.95 FALSE
10 GTEx Nerve Tibial GFPT1 0.13 0.01 lasso 4 0.02 1.8e-02 -6.5 7.2 8.9e-13 -0.87 0.03 0.90 TRUE
11 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma GFPT1 0.05 0.00 blup 67 0.02 5.9e-03 -6.5 6.9 4.0e-12 -0.87 0.01 0.78 FALSE
12 The Cancer Genome Atlas Brain Lower Grade Glioma GFPT1 0.12 0.05 blup 67 0.04 3.9e-05 -6.5 6.5 9.3e-11 -0.91 0.01 0.99 FALSE